Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Kellie L. Tuck"'
Autor:
Manja Kubeil, Irma Ivette Santana Martínez, Michael Bachmann, Klaus Kopka, Kellie L. Tuck, Holger Stephan
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 432 (2022)
Molecular imaging offers the possibility to investigate biological and biochemical processes non-invasively and to obtain information on both anatomy and dysfunctions. Based on the data obtained, a fundamental understanding of various disease process
Externí odkaz:
https://doaj.org/article/ac96f5cb53204ce0a7c9cef44a2ff19a
Publikováno v:
Foods, Vol 10, Iss 9, p 2018 (2021)
The volatile profile of raw beef contains vital information related to meat quality and freshness. This qualitative study examines the effect of packaging system on the formation and release of volatile organic compounds (VOCs) from raw beef over tim
Externí odkaz:
https://doaj.org/article/ed9e4e4082df4eaaafca38cb98d3de5a
Autor:
Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4175-4198 (2015)
Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intratheca
Externí odkaz:
https://doaj.org/article/21892d83aff54ba794d77039aaca7a80
Autor:
Ellen C. Gleeson, Janease E. Graham, Sandro Spiller, Irina Vetter, Richard J. Lewis, Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2030-2045 (2015)
A set of fluorophenoxyanilides, designed to be simplified analogues of previously reported ω-conotoxin GVIA mimetics, were prepared and tested for N-type calcium channel inhibition in a SH-SY5Y neuroblastoma FLIPR assay. N-type or Cav2.2 channel is
Externí odkaz:
https://doaj.org/article/2cdb44de3de74a758f7860ce4082332a
Publikováno v:
Sensors, Vol 19, Iss 22, p 5027 (2019)
Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites. The review is divided into two subsections
Externí odkaz:
https://doaj.org/article/3739c3ae66424c449d2ab4dbe97aadf1
Autor:
Peter J. Duggan, Aijun Yang, Irina Vetter, Jeffrey R. McArthur, Richard J. Lewis, Kellie L. Tuck, Jonathan B. Baell, Charlotte Elisabet Tranberg
Publikováno v:
Marine Drugs, Vol 10, Iss 10, Pp 2349-2368 (2012)
The neuronal voltage-gated N-type calcium channel (Cav2.2) is a validated target for the treatment of neuropathic pain. A small library of anthranilamide-derived ω-Conotoxin GVIA mimetics bearing the diphenylmethylpiperazine moiety were prepared and
Externí odkaz:
https://doaj.org/article/db61d0b38a5f4d3080df9fe4138b8354
Autor:
PETER J. HAYBALL, KELLIE L. TUCK
Publikováno v:
Malaysian Journal of Pharmaceutical Sciences, Vol 5, Iss 1, Pp 33-43 (2007)
This study describes the in vitro degradation studies of the diastereomeric ketoprofen glucuronides, under physiological conditions (pH 7.4, 37°C, (R)-ketoprofen glucuronide t½ = 30 min, (S)-ketoprofen glucuronide t½ = 70 min) and the irreversible
Externí odkaz:
https://doaj.org/article/b64b24e4ad9848db97d2d7cff4ad884b
Autor:
William I. O’Malley, Riccardo Rubbiani, Margaret L. Aulsebrook, Michael R. Grace, Leone Spiccia, Kellie L. Tuck, Gilles Gasser, Bim Graham
Publikováno v:
Molecules, Vol 21, Iss 2, p 194 (2016)
A new bifunctional macrocyclic chelator featuring a conjugatable alkynyl-naphthalimide fluorophore pendant group has been prepared and its Gd(III) complex coupled to a cell-penetrating lipidated azido-Tat peptide derivative using Cu(I)-catalysed “c
Externí odkaz:
https://doaj.org/article/d85661e76ea74089aff3dd7f6ee1caa2
Autor:
Kellie L. Tuck, Michael D. Ludden, Jack C. Dorrat, Jennifer S. Train, Michael D. Ward, Christopher G. P. Taylor, Max B. Tipping, Nicholas H. Williams
Publikováno v:
Chemical Science
An octanuclear M8L12 coordination cage catalyses the Kemp elimination reaction of 5-nitro-1,2-benzisoxazole (NBI) with hydroxide to give 2-cyano-4-nitrophenolate (CNP) as the product. In contrast to the previously-reported very efficient catalysis of
Autor:
Calum S.G. Butler, Joshua B. Marlow, Liliana de Campo, Luke W. Giles, Joshua P. King, Mark Louis P. Vidallon, Kellie L. Tuck, Anna Sokolova, Rico F. Tabor
Publikováno v:
Journal of Colloid and Interface Science. 594:669-680
Hypothesis Morphology of surfactant self-assemblies are governed by the intermolecular interactions and packing constraints of the constituent molecules. Therefore, rational design of surfactant structure should allow targeting of the specific self-a