Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kellie L. Bodeker"'
Autor:
Jianling Bi, Emily Witt, Megan K. McGovern, Arielle B. Cafi, Lauren L. Rosenstock, Anna B. Pearson, Timothy J. Brown, Thomas B. Karasic, Lucas C. Absler, Srija Machkanti, Hannah Boyce, David Gallo, Sarah L. Becker, Keiko Ishida, Joshua Jenkins, Alison Hayward, Alexandra Scheiflinger, Kellie L. Bodeker, Ritesh Kumar, Scott K. Shaw, Salma K. Jabbour, Vitor A. Lira, Michael D. Henry, Michael S. Tift, Leo E. Otterbein, Giovanni Traverso, James D. Byrne
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Modulation of autophagy, specifically its inhibition, stands to transform the capacity to effectively treat a broad range of cancers. However, the clinical efficacy of autophagy inhibitors has been inconsistent. To delineate clinical and epi
Externí odkaz:
https://doaj.org/article/f858b9587aa7486a8b205a415ae94226
Autor:
Muhammad Furqan, Taher Abu-Hejleh, Laura M. Stephens, Stacey M. Hartwig, Sarah L. Mott, Casey F. Pulliam, Michael Petronek, John B. Henrich, Melissa A. Fath, Jon C. Houtman, Steven M. Varga, Kellie L. Bodeker, Aaron D. Bossler, Andrew M. Bellizzi, Jun Zhang, Varun Monga, Hariharasudan Mani, Marina Ivanovic, Brian J. Smith, Margaret M. Byrne, William Zeitler, Brett A. Wagner, Garry R. Buettner, Joseph J. Cullen, John M. Buatti, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102318- (2022)
Purpose: Platinum-based chemotherapy with or without immunotherapy is the mainstay of treatment for advanced stage non-small cell lung cancer (NSCLC) lacking a molecular driver alteration. Pre-clinical studies have reported that pharmacological ascor
Externí odkaz:
https://doaj.org/article/3029ad560b984a928c853c72d0650fca
Autor:
Cameron M. Cushing, Michael S. Petronek, Kellie L. Bodeker, Sandy Vollstedt, Heather A. Brown, Emyleigh Opat, Nancy J. Hollenbeck, Thomas Shanks, Daniel J. Berg, Brian J. Smith, Mark C. Smith, Varun Monga, Muhammad Furqan, Matthew A. Howard, Jeremy D. Greenlee, Kranti A. Mapuskar, Joel St-Aubin, Ryan T. Flynn, Joseph J. Cullen, Garry R. Buettner, Douglas R. Spitz, John M. Buatti, Bryan G. Allen, Vincent A. Magnotta
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101804- (2021)
Pharmacological ascorbate (P-AscH-) combined with standard of care (SOC) radiation and temozolomide is being evaluated in a phase 2 clinical trial (NCT02344355) in the treatment of glioblastoma (GBM). Previously published data demonstrated that param
Externí odkaz:
https://doaj.org/article/ab946eefd1804c1cbcca282d6397675a
Autor:
Joseph J. Cullen, Bryan G. Allen, Heather A. Brown, Sandy Vollstedt, Kellie L. Bodeker, Daniel J. Berg, John M. Buatti, Douglas R. Spitz, Brianne R. O’Leary, Katherine Gibson-Corley, Juan Du, Brett A. Wagner, Garry R. Buettner, Samuel R. Schroeder, Justin G. Wilkes, Matthew S. Alexander
Radiation induced intestinal damage histology and collagen deposition information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007e7e320ffa5f1cd07d7839b75a3af6
https://doi.org/10.1158/0008-5472.22420140
https://doi.org/10.1158/0008-5472.22420140
Autor:
John M. Buatti, Douglas R. Spitz, Brian J. Smith, Mindi J. TenNapel, Garry R. Buettner, Brett A. Wagner, Daniel Berg, Joseph J. Cullen, Karra A. Jones, Joseph M. Caster, Steven N. Seyedin, Kranti A. Mapuskar, Matthew A. Howard, Jeremy D. Greenlee, Sandy Vollstedt, Nancy Hollenbeck, Heather Brown, Thomas Carlisle, Raymond Hohl, Sonia Sandhu, Varun Monga, Mark C. Smith, Kellie L. Bodeker, Bryan G. Allen
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17917570b05b73686ade6fb05c5c34d9
https://doi.org/10.1158/1078-0432.22471338.v1
https://doi.org/10.1158/1078-0432.22471338.v1
Autor:
Joseph J. Cullen, Bryan G. Allen, Heather A. Brown, Sandy Vollstedt, Kellie L. Bodeker, Daniel J. Berg, John M. Buatti, Douglas R. Spitz, Brianne R. O’Leary, Katherine Gibson-Corley, Juan Du, Brett A. Wagner, Garry R. Buettner, Samuel R. Schroeder, Justin G. Wilkes, Matthew S. Alexander
The effect of ascorbate and catalase on clonogenic cell survival in PDAC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f06878d41c887f75876ffc980c62e2b
https://doi.org/10.1158/0008-5472.22420149
https://doi.org/10.1158/0008-5472.22420149
Autor:
John M. Buatti, Douglas R. Spitz, Brian J. Smith, Mindi J. TenNapel, Garry R. Buettner, Brett A. Wagner, Daniel Berg, Joseph J. Cullen, Karra A. Jones, Joseph M. Caster, Steven N. Seyedin, Kranti A. Mapuskar, Matthew A. Howard, Jeremy D. Greenlee, Sandy Vollstedt, Nancy Hollenbeck, Heather Brown, Thomas Carlisle, Raymond Hohl, Sonia Sandhu, Varun Monga, Mark C. Smith, Kellie L. Bodeker, Bryan G. Allen
Supplemental Figure 1: P-AscH- treatment in combination with RT and TMZ decreases the systemic the systemic oxidaitive stress marker 4-hydroxy-2-nonenal modified proteins. S1A-SAB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a1a10c15be197e7e5655b0b9f05e65
https://doi.org/10.1158/1078-0432.22471341.v1
https://doi.org/10.1158/1078-0432.22471341.v1
Autor:
Joseph J. Cullen, Bryan G. Allen, Heather A. Brown, Sandy Vollstedt, Kellie L. Bodeker, Daniel J. Berg, John M. Buatti, Douglas R. Spitz, Brianne R. O’Leary, Katherine Gibson-Corley, Juan Du, Brett A. Wagner, Garry R. Buettner, Samuel R. Schroeder, Justin G. Wilkes, Matthew S. Alexander
Chemoradiation therapy is the mainstay for treatment of locally advanced, borderline resectable pancreatic cancer. Pharmacologic ascorbate (P-AscH−, i.e., intravenous infusions of ascorbic acid, vitamin C), but not oral ascorbate, produces high pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa25ab339c827584a92b1e81f77dd312
https://doi.org/10.1158/0008-5472.c.6510567.v1
https://doi.org/10.1158/0008-5472.c.6510567.v1
Autor:
John M. Buatti, Douglas R. Spitz, Brian J. Smith, Mindi J. TenNapel, Garry R. Buettner, Brett A. Wagner, Daniel Berg, Joseph J. Cullen, Karra A. Jones, Joseph M. Caster, Steven N. Seyedin, Kranti A. Mapuskar, Matthew A. Howard, Jeremy D. Greenlee, Sandy Vollstedt, Nancy Hollenbeck, Heather Brown, Thomas Carlisle, Raymond Hohl, Sonia Sandhu, Varun Monga, Mark C. Smith, Kellie L. Bodeker, Bryan G. Allen
Purpose:Standard treatment for glioblastoma (GBM) includes surgery, radiation therapy (RT), and temozolomide (TMZ), yielding a median overall survival (OS) of approximately 14 months. Preclinical models suggest that pharmacologic ascorbate (P-AscH−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bbe6e59d2bebc3dd25985ca36d230e
https://doi.org/10.1158/1078-0432.c.6527853
https://doi.org/10.1158/1078-0432.c.6527853
Autor:
John M. Buatti, Douglas R. Spitz, Brian J. Smith, Mindi J. TenNapel, Garry R. Buettner, Brett A. Wagner, Daniel Berg, Joseph J. Cullen, Karra A. Jones, Joseph M. Caster, Steven N. Seyedin, Kranti A. Mapuskar, Matthew A. Howard, Jeremy D. Greenlee, Sandy Vollstedt, Nancy Hollenbeck, Heather Brown, Thomas Carlisle, Raymond Hohl, Sonia Sandhu, Varun Monga, Mark C. Smith, Kellie L. Bodeker, Bryan G. Allen
Supplementary Table 1. Description of radiation treatment volumes (GTV, CTV, and PTV) Supplementary Table 2. Description of dose to organs at risk and treatment interruptions Supplemental Table 3. Subject count for key steps within the RT-phase of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c121da5aa23f4a19577e26f5a0b5b2e
https://doi.org/10.1158/1078-0432.22471335.v1
https://doi.org/10.1158/1078-0432.22471335.v1