Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Kellie L Tuck"'
Autor:
Jessica L Porter, Nicholas J Tobias, Sacha J Pidot, Steffen Falgner, Kellie L Tuck, Andrea Vettiger, Hui Hong, Peter F Leadlay, Timothy P Stinear
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70520 (2013)
Mycolactones are polyketide-derived lipid virulence factors made by the slow-growing human pathogen, Mycobacterium ulcerans. Three unusually large and homologous plasmid-borne genes (mlsA1: 51 kb, mlsB: 42 kb and mlsA2: 7 kb) encode the mycolactone t
Externí odkaz:
https://doaj.org/article/f4488c8b8faa4147bb82d834045ccc60
Autor:
Christopher G Langendorf, Trevor L G Key, Gustavo Fenalti, Wan-Ting Kan, Ashley M Buckle, Tom Caradoc-Davies, Kellie L Tuck, Ruby H P Law, James C Whisstock
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9280 (2010)
BackgroundIn mammals succinic semialdehyde dehydrogenase (SSADH) plays an essential role in the metabolism of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) to succinic acid (SA). Deficiency of SSADH in humans results in elevated leve
Externí odkaz:
https://doaj.org/article/a516366723734c67a8727a844c5aaebb
Autor:
Kellie L. Tuck, Michael D. Ludden, Jack C. Dorrat, Jennifer S. Train, Michael D. Ward, Christopher G. P. Taylor, Max B. Tipping, Nicholas H. Williams
Publikováno v:
Chemical Science
An octanuclear M8L12 coordination cage catalyses the Kemp elimination reaction of 5-nitro-1,2-benzisoxazole (NBI) with hydroxide to give 2-cyano-4-nitrophenolate (CNP) as the product. In contrast to the previously-reported very efficient catalysis of
Autor:
Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4175-4198 (2015)
Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intratheca
Externí odkaz:
https://doaj.org/article/21892d83aff54ba794d77039aaca7a80
Autor:
Ellen C. Gleeson, Janease E. Graham, Sandro Spiller, Irina Vetter, Richard J. Lewis, Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2030-2045 (2015)
A set of fluorophenoxyanilides, designed to be simplified analogues of previously reported ω-conotoxin GVIA mimetics, were prepared and tested for N-type calcium channel inhibition in a SH-SY5Y neuroblastoma FLIPR assay. N-type or Cav2.2 channel is
Externí odkaz:
https://doaj.org/article/2cdb44de3de74a758f7860ce4082332a
Autor:
Calum S.G. Butler, Joshua B. Marlow, Liliana de Campo, Luke W. Giles, Joshua P. King, Mark Louis P. Vidallon, Kellie L. Tuck, Anna Sokolova, Rico F. Tabor
Publikováno v:
Journal of Colloid and Interface Science. 594:669-680
Hypothesis Morphology of surfactant self-assemblies are governed by the intermolecular interactions and packing constraints of the constituent molecules. Therefore, rational design of surfactant structure should allow targeting of the specific self-a
Structure-Performance Relationships for Tail Substituted Zwitterionic Betaine-Azobenzene Surfactants
Autor:
Calum S.G. Butler, Luke W. Giles, Anna V. Sokolova, Liliana de Campo, Rico F. Tabor, Kellie L. Tuck
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 38(24)
Azobenzene-containing surfactants (azo-surfactants) have garnered significant attention for their use in generating photoresponsive foams, interfaces, and colloidal systems. The photoresponsive behavior of azo-surfactants is driven by the conformatio
Publikováno v:
Sensors, Vol 19, Iss 22, p 5027 (2019)
Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites. The review is divided into two subsections
Externí odkaz:
https://doaj.org/article/3739c3ae66424c449d2ab4dbe97aadf1
Publikováno v:
ACS Sensors. 5:2523-2529
Miniaturization of sensing technology has led to the development of multifunctional micro total analysis systems (μTAS) that benefit from microfluidic technology. Optical sensing is one of the most commonly used sensing approaches integrated into μ
Autor:
Muamer Dervisevic, Victor J. Cadarso, Esma Dervisevic, Luis F. Malaver-Ortega, Yan Wang, Wenlong Cheng, Nicolas H. Voelcker, Kellie L. Tuck
Publikováno v:
Electroanalysis. 32:1850-1858