Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kellie Howard"'
Autor:
Ghideon Ezaz, Hirsh D. Trivedi, Margery A. Connelly, Claudia Filozof, Kellie Howard, Mark L.Parrish, Misung Kim, Mark A. Herman, Imad Nasser, Nezam H. Afdhal, Z. Gordon Jiang, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 4, Iss 5, Pp 670-680 (2020)
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease driven by genetic and environmental factors. MicroRNAs (miRNAs) serve as pleiotropic post‐transcriptional regulators of cellular pathways. Although several miRNAs have been associa
Externí odkaz:
https://doaj.org/article/3e31e44a9bf34567b3f367787a2d4008
Autor:
Julie F. Foley, Dhiral P. Phadke, Owen Hardy, Sara Hardy, Victor Miller, Anup Madan, Kellie Howard, Kimberly Kruse, Cara Lord, Sreenivasa Ramaiahgari, Gregory G. Solomon, Ruchir R. Shah, Arun R. Pandiri, Ronald A. Herbert, Robert C. Sills, B. Alex Merrick
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal model validation. Here, we report development and testing of a probe set f
Externí odkaz:
https://doaj.org/article/cff0d9622550409fa4a924db259dbc28
Autor:
Bernard Omolo, Mingli Yang, Fang Yin Lo, Michael J. Schell, Sharon Austin, Kellie Howard, Anup Madan, Timothy J. Yeatman
Publikováno v:
BMC Medical Genomics, Vol 9, Iss 1, Pp 1-10 (2016)
Abstract Background The KRAS gene is mutated in about 40 % of colorectal cancer (CRC) cases, which has been clinically validated as a predictive mutational marker of intrinsic resistance to anti-EGFR inhibitor (EGFRi) therapy. Since nearly 60 % of pa
Externí odkaz:
https://doaj.org/article/f3b993c8f3094656b0bf38bfaca10a06
Autor:
A Gregory Bruce, Serge Barcy, Jeannette Staheli, Helle Bielefeldt-Ohmann, Minako Ikoma, Kellie Howard, Timothy M Rose
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0205632 (2018)
Macaque RFHV and LCV are close homologs of human KSHV and EBV, respectively. No experimental model of RFHV has been developed due to the lack of a source of culturable infectious virus. Screening of macaques at the Washington National Primate Researc
Externí odkaz:
https://doaj.org/article/9b3dd1a591204c7ab4d81436f1dbb800
Autor:
Minako Ikoma, Margaret E. Thouless, A. Gregory Bruce, Helle Bielefeldt-Ohmann, Timothy M. Rose, Kellie Howard
Publikováno v:
Virology. 519:106-120
We developed a set of rabbit antisera to characterize infections by the macaque RV2 rhadinovirus homologs of KSHV. We analyzed tissues from rhesus and pig-tailed macaques naturally infected with rhesus rhadinovirus (RRV) or Macaca nemestrina rhadinov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2022b4cb50ae99b3dac18778ea10fd8
https://doi.org/10.1016/j.virol.2018.04.007
https://doi.org/10.1016/j.virol.2018.04.007
Publikováno v:
Virology. 511:152-164
The latency-associated nuclear antigens (LANA) of KSHV and macaque RFHVMn, members of the RV1 rhadinovirus lineage, are closely related with conservation of complex nuclear localization signals (NLS) containing bipartite KR-rich motifs and RG-rich do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db07c910e5d7b30c1cd04c2793637dce
https://doi.org/10.1016/j.virol.2017.08.029
https://doi.org/10.1016/j.virol.2017.08.029
Autor:
Minako Ikoma, Kellie Howard, Jeannette P. Staheli, A. Gregory Bruce, Serge Barcy, Helle Bielefeldt-Ohmann, Timothy M. Rose
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0205632 (2018)
PLoS ONE, Vol 13, Iss 11, p e0205632 (2018)
Macaque RFHV and LCV are close homologs of human KSHV and EBV, respectively. No experimental model of RFHV has been developed due to the lack of a source of culturable infectious virus. Screening of macaques at the Washington National Primate Researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a533a8b128f63a4cfc79bbbc672a67
http://europepmc.org/articles/PMC6239284
http://europepmc.org/articles/PMC6239284
Autor:
Kimberly Kruse, Arun R. Pandiri, Sreenivasa Ramaiahgari, Ruchir R. Shah, B. Alex Merrick, Anup Madan, Victor Miller, Robert C. Sills, Julie F. Foley, Sara Hardy, Gregory G. Solomon, Ronald A. Herbert, Dhiral P. Phadke, Kellie Howard, Cara Lord, Owen Hardy
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
BMC Genomics
BMC Genomics
Background The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal model validation. Here, we report development and testing of a probe set for whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf5e01f14cfb55224e27d5bb228eec1
https://doi.org/10.1186/s12864-018-4858-8
https://doi.org/10.1186/s12864-018-4858-8
Autor:
Keiji Ueda, Minako Ikoma, Serge Barcy, Ashlee V. Moses, Gail H. Deutsch, David Wu, Kellie Howard, Timothy M. Rose, H. Jacques Garrigues
Publikováno v:
Journal of Virology. 91
The latency-associated nuclear antigen (LANA) of the Kaposi's sarcoma-associated herpesvirus (KSHV) performs a variety of functions to establish and maintain KSHV latency. During latency, LANA localizes to discrete punctate spots in the nucleus, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef083899a5ba54e6d0ccf17c92c5c67d
https://doi.org/10.1128/jvi.01532-17
https://doi.org/10.1128/jvi.01532-17
Autor:
Kirsten E. Erger, Alok K. Sharma, Thomas J. Conlon, Jeffrey D. Chulay, Guo-jie Ye, David R. Knop, Peter Sonnentag, Kellie Howard
Publikováno v:
Human Gene Therapy Clinical Development. 26:177-184
Applied Genetic Technologies Corporation is developing a recombinant adeno-associated virus (rAAV) vector for treatment of X-linked retinoschisis (XLRS), an inherited retinal disease characterized by splitting (schisis) of the layers of the retina, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f23854a8b6159c38e06e60f475fe8a
https://doi.org/10.1089/humc.2015.077
https://doi.org/10.1089/humc.2015.077