Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kellie Hom"'
Autor:
Jiantao Zhang, Kellie Hom, Chenyu Zhang, Mohamed Nasr, Volodymyr Gerzanich, Yanjin Zhang, Qiyi Tang, Fengtian Xue, J. Marc Simard, Richard Y. Zhao
Publikováno v:
Pathogens, Vol 13, Iss 1, p 75 (2024)
The COVID-19 pandemic caused by SARS-CoV-2 has posed unparalleled challenges due to its rapid transmission, ability to mutate, high mortality and morbidity, and enduring health complications. Vaccines have exhibited effectiveness, but their efficacy
Externí odkaz:
https://doaj.org/article/2064859716c941f99d4567ae8e898eb7
Autor:
Andrew T. Stoltzfus, Courtney J. Campbell, Madison M. Worth, Kellie Hom, Timothy L. Stemmler, Sarah L. J. Michel
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 28:85-100
Autor:
Joel E. Graham, Dimitri Niks, Grant M. Zane, Qin Gui, Kellie Hom, Russ Hille, Judy D. Wall, C. S. Raman
Publikováno v:
ACS Catalysis. 12:10449-10471
The reversible two-electron interconversion of formate and CO2 is catalyzed by both non-metallo and metallo-formate dehydrogenases (FDHs). The latter group comprises molybdenum-or tungsten-containing enzymes with the metal coordinated by two equivale
Autor:
Kyle C. Kihn, Nicholas Montes, Kellie Hom, Wenbo Yu, Fengtian Xue, Alexander D. MacKerell, Angela Wilks, Daniel Deredge
Publikováno v:
Biophysical Journal. 122:330a
Autor:
Maureen A. Kane, Ramin Samadani, Lijia Chen, Ramon Martinez, Ivie L. Conlon, Bryan Mackowiak, Paul Shapiro, Kellie Hom, Steven Fletcher, Garrick Centola, Weiliang Huang
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Constitutively active extracellular signal-regulated kinase (ERK) 1/2 signaling promotes cancer cell proliferation and survival. We previously described a class of compounds containing a 1,1-dioxido-2,5-dihydrothiophen-3-yl 4-benzenesulfonate scaffol
Autor:
Fengtian Xue, Yong Ai, Garrick Centola, Kellie Hom, Angela Wilks, Daniel Deredge, Alecia T. Dent
Publikováno v:
ACS Infectious Diseases. 6:2073-2085
Pseudomonas aeruginosa is an opportunistic bacterium that causes life-threatening infections in immunocompromised patients. In infection, it uses heme as a primary iron source and senses the availability of exogenous heme through the heme assimilatio
Autor:
Garrick, Centola, Daniel J, Deredge, Kellie, Hom, Yong, Ai, Alecia T, Dent, Fengtian, Xue, Angela, Wilks
Publikováno v:
ACS Infect Dis
Pseudomonas aeruginosa is an opportunistic bacterium that causes life-threatening infections in immunocompromised patients. In infection, it uses heme as a primary iron source and senses the availability of exogenous heme through the heme assimilatio
Autor:
Kellie Hom, Mohd. Imran Ansari, Jeffrey R. Deschamps, Rae R. Matsumoto, Jason R. Healy, Andrew Coop
Publikováno v:
Organic Letters. 20:2984-2987
During optimization of the synthesis of the mixed μ opioid agonist/δ opioid antagonist 5-(hydroxymethyl)oxymorphone (UMB425) for scale-up, it was unexpectedly discovered that the 4,5-epoxy bridge underwent rearrangement on treatment with boron trib
Autor:
Yue Li, Nam Nguyen, Qianshou Zong, Angela Wilks, Elizabeth Robinson, Fengtian Xue, Wenbo Yu, Kellie Hom, Dongdong Liang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1024-1029
[Image: see text]
Autor:
Jason D. Kahn, A. James Mixson, Szu-Ting Chou, Lucas Tricoli, Joonil Seog, Daoning Zhang, Amy Lee, Qixin Leng, Jason M. Hustedt, Michael J. Shapiro, Kellie Hom
Publikováno v:
Biomaterials. 35:846-855
Branched peptides containing histidines and lysines (HK) have been shown to be effective carriers for DNA and siRNA. We anticipate that elucidation of the binding mechanism of HK with siRNA will provide greater insight into the self-assembly and deli