Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kellie Bruening"'
Autor:
Ronald Sobecks, Jerome B. Zeldis, Matt Kalaycio, Janice Reed, Aleksandr Lazaryan, Steven Andresen, Rachid Baz, Kimberly Hamilton, Beth Faiman, Mary Ann Karam, Joel Waksman, Gordan Srkalovic, Frederic J. Reu, John Sweetenham, Robert M. Dean, Robert Knight, Becky Habecker, Kellie Bruening, Mohamad A. Hussein
Publikováno v:
American Journal of Hematology. 89:349-354
A previous interim report of MM-011, the first study that combined lenalidomide with anthracycline-based chemotherapy followed by lenalidomide maintenance for relapsed and/or refractory multiple myeloma (RRMM), showed promising safety and activity. W
Autor:
Aleksandr, Lazaryan, Mohamad A, Hussein, Frederic J, Reu, Beth, Faiman, Becky, Habecker, Mary, Ann Karam, Janice, Reed, Kimberly, Hamilton, Joel, Waksman, Kellie, Bruening, Gordan, Srkalovic, Steven, Andresen, Matthew, Kalaycio, John W, Sweetenham, Ronald, Sobecks, Robert, Dean, Robert, Knight, Jerome B, Zeldis, Rachid, Baz
Publikováno v:
American journal of hematology. 89(4)
A previous interim report of MM-011, the first study that combined lenalidomide with anthracycline-based chemotherapy followed by lenalidomide maintenance for relapsed and/or refractory multiple myeloma (RRMM), showed promising safety and activity. W
Autor:
M. A. Karam, J. Zeldis, Mohamad A. Hussein, G Srkalovic, Y Ellis, Robert Knight, Rony Abou Jawde, Janice Reed, Toni K. Choueiri, Esteban Walker, Kellie Bruening, Steven Andresen, Catherine Brand, Beth Faiman, Rachid Baz
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 17(12)
Background Lenalidomide is active and well tolerated in relapsed and refractory multiple myeloma. We conducted a phase I/II trial of the combination of lenalidomide and chemotherapy to evaluate the safety and efficacy of the combination. Methods The
Autor:
Mitchell R. Smith, Christy J. Samaras, Robert M. Dean, Debbie Hastings, Frederic J. Reu, Jason Valent, Hien K. Duong, Paul Elson, Surbhi Sidana, Kellie Bruening, Beth Faiman
Publikováno v:
Blood. 122:1975-1975
Background Information is limited on the efficacy and long-term tolerability of weekly ubcutaneous (SC) bortezomib (BTZ), especially when given alone or combined only with glucocorticoids. We implemented use of SC BTZ in 12/2010 and based on equal AU
Autor:
Beth Faiman, Robert M. Dean, Hien K. Duong, Mitchell R. Smith, Paul Elson, Debbie Hastings, Kellie Bruening, Christy J. Samaras, Frederic J. Reu, Jason Valent, Surbhi Sidana
Publikováno v:
Blood. 122:5397-5397
Background We hypothesized lenalidomide (len) related diarrhea (LRD) may correlate with activation of an immune response against multiple myeloma (MM) based on colon biopsies that showed crypt apoptosis reminiscent of GVHD in 3 MM patients with sever
Autor:
Kimberly Hamilton, Jerome B. Zeldis, Rachid Baz, Gordan Srkalovic, Mohamad A. Hussein, Ronald Sobecks, Aleksandr Lazaryan, Becky Habecker, Robert M. Dean, Mary Ann Karam, Robert Knight, Steven Andresen, John Sweetenham, Frederic J. Reu, Janice Reed, Matt Kalaycio, Paul Elson, Beth Faiman, Kellie Bruening
Publikováno v:
Blood. 116:1967-1967
Abstract 1967 Background: An initial report of MM011 described the MTD and promising activity in the first 62 patients (pts) (Baz R et al, Ann Oncol 2006). Here we report complete outcomes of the entire study cohort (n=77) with over four years since
Autor:
Kathe Balinski, Janice Reed, Greg L. Pearce, Mohamad A. Hussein, Kellie Bruening, Marta Olesnyckyj, Paul Sartori, Jerome B. Zeldis, Mary Ann Karam, Robert Knight, Catherine Brand, Gordan Srkalovic
Publikováno v:
Blood. 104:208-208
DVd in combination with Thalidomide (T) and the appropriate supportive care measures resulted in a high response rate (88%) as well as an improved quality response (50% CR & NCR) similar to what is achieved with high dose therapy. Immunomodulatory dr