Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Kelli P A, MacDonald"'
Autor:
Sahar Keshvari, Berit Genz, Ngari Teakle, Melanie Caruso, Michelle F. Cestari, Omkar L. Patkar, Brian W. C. Tse, Kamil A. Sokolowski, Hilmar Ebersbach, Julia Jascur, Kelli P. A. MacDonald, Gregory Miller, Grant A. Ramm, Allison R. Pettit, Andrew D. Clouston, Elizabeth E. Powell, David A. Hume, Katharine M. Irvine
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 4 (2022)
Resident and recruited macrophages control the development and proliferation of the liver. We have previously shown in multiple species that treatment with a macrophage colony stimulating factor (CSF1)-Fc fusion protein initiated hepatocyte prolifera
Externí odkaz:
https://doaj.org/article/9b4f9a4ccdaa4fd4b6ee2680c8ac5715
Autor:
Jemma Nicholls, Benjamin Cao, Laetitia Le Texier, Laura Yan Xiong, Christopher R. Hunter, Genesis Llanes, Ethan G. Aguliar, Wayne A. Schroder, Simon Phipps, Jason P. Lynch, Huimin Cao, Shen Y. Heazlewood, Brenda Williams, Andrew D. Clouston, Christian M. Nefzger, Jose M. Polo, Susan K. Nilsson, Bruce R. Blazar, Kelli P. A. MacDonald
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Regulatory T cell (Treg) reconstitution is essential for reestablishing tolerance and maintaining homeostasis following stem-cell transplantation. We previously reported that bone marrow (BM) is highly enriched in autophagy-dependent Treg and autopha
Externí odkaz:
https://doaj.org/article/27d02299a5ee475cab524537e8e3a0b4
Autor:
Dylan Carter-Cusack, Jana Vukovic, Rachael C Adams, Bruce R. Blazar, Glen M. Boyle, Andreas Möller, Kelli P. A. MacDonald, Genesis T Llanes, Rebecca L Johnston, Samreen Shaikh, Gregory A. Quaife-Ryan, Lambros T. Koufariotis
Publikováno v:
Blood. 139:1389-1408
Graft-versus-host disease (GVHD) remains the leading cause of nonrelapse mortality after allogeneic stem cell transplantation for hematological malignancies. Manifestations of GVHD in the central nervous system (CNS) present as neurocognitive dysfunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea118ad90d72ae5b9f675ce5efb04e8
https://doi.org/10.1182/blood.2021011671
https://doi.org/10.1182/blood.2021011671
Autor:
D. Pulanić, Nataliya Prokopenko Buxbaum, Joerg Halter, Joseph Pidala, Lori Henderson, Stefanie Sarantopoulos, Yoshihiro Inamoto, Amin M. Alousi, Ted Gooley, Steven Z. Pavletic, Kelli P. A. MacDonald, Vijaya Raj Bhatt, Corey Cutler, Daniel R. Couriel, Attilio Olivieri, Bruce R. Blazar, Sophie Paczesny, Paul J. Martin, Kirk R. Schultz, Aleksandr Lazaryan, Carrie L. Kitko, Hildegard Greinix, Stephanie J. Lee, Zachariah DeFilipp, Daniel Wolff, Robert Zeiser, Gérard Socié
Publikováno v:
Transplant Cell Ther
Positive results from recent clinical trials have significantly expanded current therapeutic options for patients with chronic graft-versus-host disease (GVHD). However, new insights into the associations between clinical characteristics of chronic G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41efaff68e20ebd6804873fb7372ac4f
https://doi.org/10.1016/j.jtct.2021.05.004
https://doi.org/10.1016/j.jtct.2021.05.004
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Regulatory T cells (Tregs) are key mediators of the immune system. MicroRNAs (miRNAs) are a family of ~22 nucleotide non-coding RNAs that are processed from longer precursors by the RNases Drosha and Dicer. miRNA regulates protein expression posttran
Externí odkaz:
https://doaj.org/article/aaffc48bb9644c21a7c85844da35dd9a
Autor:
Randolph J. Noelle, Roshantha A.S. Chandraratna, Amanda Janesick, Ethan G. Aguilar, Kelli P. A. MacDonald, Asim Saha, Bruce R. Blazar, Keli L. Hippen, Michael Loschi, Govindarajan Thangavelu, Kazutoshi Aoyama, Geoffrey R. Hill, Angela Panoskaltsis-Mortari, Vijay K. Kuchroo, Yosef Refaeli, Bruce Blumberg, Chrysothemis C. Brown, Scott N. Furlan, William J. Murphy, David H. Munn, Jonathan S. Serody, Cameron McDonald-Hyman, Chao Wang, Ivan Maillard, Leslie S. Kean, Robert Zeiser, Mark J. Osborn
Publikováno v:
Blood. 137:1090-1103
The nuclear receptor (NR) subclass, retinoid X receptors (RXRs), exert immunomodulatory functions that control inflammation and metabolism via homodimers and heterodimers, with several other NRs, including retinoic acid receptors. IRX4204 is a novel,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0f3302c269d7174eef13fea11aefd7
https://doi.org/10.1182/blood.2020005628
https://doi.org/10.1182/blood.2020005628
Autor:
Kate H. Gartlan, Slavica Vuckovic, Karshing Chang, Glen M. Boyle, Vivien R. Sutton, Mark J. Smyth, Melody Cheong, Ping Zhang, Motoko Koyama, Kelli P. A. MacDonald, José Paulo Martins, Christopher E. Andoniou, Joseph A. Trapani, Geoffrey R. Hill, Antiopi Varelias, Greg Kelly, Kate A. Markey, Rachel D. Kuns, Siok-Keen Tey, Mariapia A. Degli-Esposti, Jason Sang Hun Lee, Christian R. Engwerda
Publikováno v:
Cancer Immunology Research. 8:1085-1098
The adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD) is known to facilitate caspase-1 activation, which is essential for innate host immunity via the formation of the inflammasome complex, a multiprotein structure respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2020faa108fc8bfafac1952dcfbe688
https://doi.org/10.1158/2326-6066.cir-19-0653
https://doi.org/10.1158/2326-6066.cir-19-0653
Autor:
Ngari Teakle, Julia Jascur, Kamil A. Sokolowski, Allison R. Pettit, Katharine M. Irvine, Brian W.C. Tse, Hilmar Ebersbach, Omkar L. Patkar, Melanie Caruso, Gregory M. Miller, Kelli P. A. MacDonald, Sahar Keshvari, David A. Hume, Grant A. Ramm, Elizabeth E. Powell, Andrew D. Clouston, Berit Genz, Michelle Ferrari Cestari
Resident and recruited macrophages control the development and proliferation of the liver. We showed previously in multiple species that treatment with a macrophage colony stimulating factor (CSF1)-Fc fusion protein initiated hepatocyte proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6327b3b4cebf27a08d91c4921bb870a8
https://doi.org/10.1101/2021.11.07.467663
https://doi.org/10.1101/2021.11.07.467663
Autor:
Michael C. Zaiken, Ryan Flynn, Katelyn G. Paz, Stephanie Y. Rhee, Sujeong Jin, Fathima A. Mohamed, Asim Saha, Govindarajan Thangavelu, Paul M. C. Park, Matthew L. Hemming, Peter T. Sage, Arlene H. Sharpe, Michel DuPage, Jeffrey A. Bluestone, Angela Panoskaltsis-Mortari, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Leo Luznik, Ivan Maillard, Geoffrey R. Hill, Kelli P. A. MacDonald, David H. Munn, Jonathan S. Serody, William J. Murphy, Leslie S. Kean, Yi Zhang, James E. Bradner, Jun Qi, Bruce R. Blazar
Publikováno v:
Blood. 139(19)
Despite advances in the field, chronic graft-versus-host-disease (cGVHD) remains a leading cause of morbidity and mortality following allogenic hematopoietic stem cell transplant. Because treatment options remain limited, we tested efficacy of antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8789c02293084d644b919d40fc5faec8
https://pubmed.ncbi.nlm.nih.gov/35552645
https://pubmed.ncbi.nlm.nih.gov/35552645
Autor:
Martin J. Auldist, J.A.S. Lancaster, Kelli P. A. MacDonald, A.M. Bryant, O.K. Spaans, John R Roche, M. Neal, G.J. Doole
Publikováno v:
Journal of Dairy Science. 102:11523-11535
In theory, a late winter–early spring calving date in temperate grazing systems best matches pasture supply and herd demand, thereby minimizing the need for nonpasture feeds and maximizing profitability. We used a quantitative case study approach t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f171913699414883ec90fea80c036fe
https://doi.org/10.3168/jds.2018-15911
https://doi.org/10.3168/jds.2018-15911