Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Kelli L Boyd"'
Autor:
Ly Pham, Padmini Komalavilas, Alex M. Eddie, Timothy E. Thayer, Dalton L. Greenwood, Ken H. Liu, Jaclyn Weinberg, Andrew Patterson, Joshua P. Fessel, Kelli L. Boyd, Jenny C. Schafer, Jamie L. Kuck, Aaron C. Shaver, David K. Flaherty, Brittany K. Matlock, Christiaan D. M. Wijers, C. Henrique Serezani, Dean P. Jones, Evan L. Brittain, Jeffrey C. Rathmell, Michael J. Noto
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Cpt1a-dependent fatty acid beta-oxidation is found to regulate neutrophil trafficking to the site of infection in a mouse model of pneumonia and is found to play a role in pneumonia susceptibility in humans.
Externí odkaz:
https://doaj.org/article/d76a7386c54d4c2f854b839fc40b5550
Autor:
Yan Liu, Jozef Zienkiewicz, Huan Qiao, Katherine N. Gibson-Corley, Kelli L. Boyd, Ruth Ann Veach, Jacek Hawiger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Atopic Dermatitis (AD) or eczema, a recurrent allergic inflammation of the skin, afflicts 10–20% of children and 5% adults of all racial and ethnic groups globally. We report a new topical treatment of AD by a Nuclear Transport Checkpoint
Externí odkaz:
https://doaj.org/article/6c7e591c508045cfb18112d5daf1ccda
Autor:
Michelle L. Korir, Ryan S. Doster, Jacky Lu, Miriam A. Guevara, Sabrina K. Spicer, Rebecca E. Moore, Jamisha D. Francis, Lisa M. Rogers, Kathryn P. Haley, Amondrea Blackman, Kristen N. Noble, Alison J. Eastman, Janice A. Williams, Steven M. Damo, Kelli L. Boyd, Steven D. Townsend, C. Henrique Serezani, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Perinatal infection with Group B Streptococcus (GBS) is associated with preterm birth, neonatal sepsis, and stillbirth. Here, Korir et al. show that gene cadD, encoding a putative metal efflux transporter, is important for metal detoxification, immun
Externí odkaz:
https://doaj.org/article/597dc8cb42f34cfcbcc7b2c564bd3327
Autor:
Clayton B. Marshall, J. Scott Beeler, Brian D. Lehmann, Paula Gonzalez-Ericsson, Violeta Sanchez, Melinda E. Sanders, Kelli L. Boyd, Jennifer A. Pietenpol
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Abstract p73 and p63 are members of the p53 family that exhibit overlapping and distinct functions in development and homeostasis. The evaluation of p73 and p63 isoform expression across human tissue can provide greater insight to the functional inte
Externí odkaz:
https://doaj.org/article/48dd852c2c7246bc9d0f0a7898b613f1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Hyperlipidemia, the hallmark of Metabolic Syndrome that afflicts millions of people worldwide, exacerbates life-threatening infections. We present a new evidence for the mechanism of hyperlipidemic hypersensitivity to microbial inflammation
Externí odkaz:
https://doaj.org/article/5a9a67ba778d477782a1456528d9f96b
Autor:
Clinton M. Hasenour, Arion J. Kennedy, Tomasz Bednarski, Irina A. Trenary, Brandon J. Eudy, Robin P. da Silva, Kelli L. Boyd, Jamey D. Young
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 707-721 (2020)
Fatty liver involves ectopic lipid accumulation and dysregulated hepatic oxidative metabolism, which can progress to a state of elevated inflammation and fibrosis referred to as nonalcoholic steatohepatitis (NASH). The factors that control progressio
Externí odkaz:
https://doaj.org/article/00483672a33b4e59bd5bd114c8ed4600
Autor:
M Indriati Hood-Pishchany, Ly Pham, Christiaan D Wijers, William J Burns, Kelli L Boyd, Lauren D Palmer, Eric P Skaar, Michael J Noto
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008374 (2020)
Antimicrobial resistance is increasing in pathogenic bacteria. Yet, the effect of antibiotic exposure on resistant bacteria has been underexplored and may affect pathogenesis. Here we describe the discovery that propagation of the human pathogen Acin
Externí odkaz:
https://doaj.org/article/f87d42f8b1cf45e0aa68e69dba22845b
Autor:
Gabriela L. Santos Guasch, J Scott Beeler, Clayton B. Marshall, Timothy M. Shaver, Quanhu Sheng, Kimberly N. Johnson, Kelli L. Boyd, Bryan J. Venters, Rebecca S. Cook, Jennifer A. Pietenpol
Publikováno v:
iScience, Vol 8, Iss , Pp 236-249 (2018)
Summary: We report that p73 is expressed in ovarian granulosa cells and that loss of p73 leads to attenuated follicle development, ovulation, and corpus luteum formation, resulting in decreased levels of circulating progesterone and defects in mammar
Externí odkaz:
https://doaj.org/article/79bbd3f5a5444de6bcdc0ceb0648766e
Autor:
Jacqueline-Yvonne Cephus, Matthew T. Stier, Hubaida Fuseini, Jeffrey A. Yung, Shinji Toki, Melissa H. Bloodworth, Weisong Zhou, Kasia Goleniewska, Jian Zhang, Sarah L. Garon, Robert G. Hamilton, Vasiliy V. Poloshukin, Kelli L. Boyd, R. Stokes Peebles, Jr., Dawn C. Newcomb
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2487-2499 (2017)
Sex hormones regulate many autoimmune and inflammatory diseases, including asthma. As adults, asthma prevalence is 2-fold greater in women compared to men. The number of group 2 innate lymphoid cells (ILC2) is increased in patients with asthma, and w
Externí odkaz:
https://doaj.org/article/87fabe7a1e54432baf5024d79aed6767
Autor:
Michael R. Savona, Stephen W. Fesik, Edward T. Olejniczak, Gregory D. Ayers, Leah J. Hogdal, John Sensintaffar, Stephen A. Strickland, Kelli L. Boyd, Londa Fuller, Maria Pia Arrate, Agnieszka E. Gorska, Taekyu Lee, Melissa A. Fischer, Haley E. Ramsey
Supplementary figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a65705db4645e57301fe7bf49f1478
https://doi.org/10.1158/2159-8290.22534147.v1
https://doi.org/10.1158/2159-8290.22534147.v1
