Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kelli E. Smith"'
Autor:
William B Vanti, Sujata Swaminathan, Richard Blevins, James A Bonini, Brian F O'Dowd, Susan R George, Richard L Weinshank, Kelli E Smith, Wendy J Bailey
Publikováno v:
Expert Opinion on Therapeutic Patents. 11:1861-1887
A paradigm shift has occurred in the post-genomic age where genes are rapidly identified using homology based experimental and computational approaches. The intellectual property (IP) rights to these genes as research tools has changed the nature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5f4f8e0d935141236a324b2d28e149
https://doi.org/10.1517/13543776.11.12.1861
https://doi.org/10.1517/13543776.11.12.1861
Autor:
Joseph A. Tamm, Noel Boyle, Pierre J.-J. Vaysse, Nika Adham, Wen-Jeng Yao, Carlos Forray, John M. Wetzel, Parul P. Lakhlani, Margaret M. Durkin, Roman Artymyshyn, Evguenia V. Kouranova, Yong Quan, Kelli E. Smith, Kenneth A. Jones, Rita Raddatz, Theresa Branchek, Christophe P. G. Gerald, James A. Bonini, Kristine L. Ogozalek, Lakmal W. Boteju, Beth Borowsky
Publikováno v:
Journal of Biological Chemistry. 275:39324-39331
The central nervous system octapeptide, neuropeptide FF (NPFF), is believed to play a role in pain modulation and opiate tolerance. Two G protein-coupled receptors, NPFF1 and NPFF2, were isolated from human and rat central nervous system tissues. NPF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5a488ab332b9fe290d764d964bd5d1
https://doi.org/10.1074/jbc.m004385200
https://doi.org/10.1074/jbc.m004385200
Autor:
Christophe P. G. Gerald, Kelli E. Smith, Theresa Branchek, Eric L. Gustafson, Mary W. Walker, Margaret M. Durkin
Publikováno v:
Experimental Neurology. 165:90-100
Our group has reported on the cloning of a novel rat neuropeptide Y (NPY) receptor involved in NPY-induced food intake, the Y5 receptor. The distribution in rat brain of the mRNA encoding this receptor has been determined by in situ hybridization his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c5d13130d8466127aa3b4fe85e6108
https://doi.org/10.1006/exnr.2000.7446
https://doi.org/10.1006/exnr.2000.7446
Publikováno v:
Annals of the New York Academy of Sciences. 863:94-107
Galanin was first isolated 15 years ago. Diversity of galanin receptors has been suspected from the study of native tissues and functional responses to galanin and galanin-like peptides in vitro and in vivo. The recent application of molecular biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9588c12156f337fb9411a7d4e26d248
https://doi.org/10.1111/j.1749-6632.1998.tb10687.x
https://doi.org/10.1111/j.1749-6632.1998.tb10687.x
Autor:
Pierre J.-J. Vaysse, Jonathan A. Bard, Wen-Jeng Yao, Christophe P. G. Gerald, Roman Artymyshyn, Beth Borowsky, Kelli E. Smith, Joseph A. Tamm, Theresa Branchek, Mary W. Walker, Kenneth A. Jones
Publikováno v:
Journal of Biological Chemistry. 273:23321-23326
The neuropeptide galanin has been implicated in the regulation of processes such as nociception, cognition, feeding behavior, and hormone secretion. Multiple galanin receptors are predicted to mediate its effects, but only two functionally coupled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9bd37bf546696b371e37cc270d74773
https://doi.org/10.1074/jbc.273.36.23321
https://doi.org/10.1074/jbc.273.36.23321
Autor:
Christophe P. G. Gerald, Jonathan A. Bard, Kelli E. Smith, Beth Borowsky, Kenneth A. Jones, Ling-Yan Huang, Mary W. Walker, Theresa Branchek
Publikováno v:
Peptides. 19:1771-1781
We present the molecular cloning and characterization of the human galanin receptor, hGALR2. hGALR2 shares 85%, 39%, and 57% amino acid identities to rGALR2, hGALR1, and hGALR3, respectively. hGALR2, along with rGALR2, can be distinguished from the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247edf96a3c90cbf25ef537d1d4f1282
https://doi.org/10.1016/s0196-9781(98)00133-8
https://doi.org/10.1016/s0196-9781(98)00133-8
Autor:
Carlos Forray, Jonathan A. Bard, Joseph A. Tamm, Mary W. Walker, David L. Linemeyer, Kelli E. Smith, Kenneth A. Jones, Theresa Branchek, Christophe P. G. Gerald
Publikováno v:
Journal of Biological Chemistry. 272:24612-24616
The neuropeptide galanin is widely distributed throughout the central and peripheral nervous systems and participates in the regulation of processes such as nociception, cognition, feeding behavior, and insulin secretion. Multiple galanin receptors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aabb2a0028703beeebd34d802d6d7cf
https://doi.org/10.1074/jbc.272.39.24612
https://doi.org/10.1074/jbc.272.39.24612
Autor:
Jonathan A. Bard, Sherif Daouti, Pierre J.-J. Vaysse, Kelli E. Smith, Theresa Branchek, Mary W. Walker, Richard L. Weinshank, Christophe P. G. Gerald
Publikováno v:
Peptides. 18:609-612
We cloned and expressed the rat Y4 receptor for pancreatic polypeptide (PP). Structure-activity profiles derived from 125I-PP binding assays and [cAMP] radioimmunoassays reveal a selective receptor interaction with rat PP vs. neuropeptide Y (NPY) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fad780476a62e6267acb68f309c2711
https://doi.org/10.1016/s0196-9781(97)00070-3
https://doi.org/10.1016/s0196-9781(97)00070-3
Autor:
Leoluca Criscione, Richard L. Weinshank, Robert I. Taber, Christine Batzl-Hartmann, Eric L. Gustafson, Thomas M. Laz, Andrea O. Schaffhauser, Pierre J.-J. Vaysse, Margaret M. Durkin, David L. Linemeyer, Kelli E. Smith, Steven Whitebread, K. G. Hofbauer, Mary W. Walker, Theresa A. Branchek, Christophe P. G. Gerald
Publikováno v:
Nature. 382:168-171
Neuropeptide Y (NPY) is a powerful stimulant of food intake and is proposed to activate a hypothalamic 'feeding' receptor distinct from previously cloned Y-type receptors. This receptor was first suggested to explain a feeding response to NPY and rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a093719ce26d6c1c352a6f678ec635d
https://doi.org/10.1038/382168a0
https://doi.org/10.1038/382168a0
Autor:
Margaret M. Durkin, Richard L. Weinshank, Laurence A. Borden, Theresa Branchek, Eric L. Gustafson, Kelli E. Smith
Publikováno v:
Molecular Brain Research. 33:7-21
Localization of the messenger RNAs encoding three γ-aminobutyric acid (GABA) transporters, termed GAT-1, GAT-2, and GAT-3, has been carried out in rat brain using radiolabeled oligonucleotide probes and in situ hybridization histochemistry. Hybridiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3866f0299c8e0aedab93b89b1abf68
https://doi.org/10.1016/0169-328x(95)00101-w
https://doi.org/10.1016/0169-328x(95)00101-w