Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kelli, Odoms"'
Autor:
Basilia Zingarelli, Katherine E. Dunsmore, Alvin Denenberg, Patrick D. Solan, Kelli Odoms, Hector R. Wong
Publikováno v:
Critical Care Medicine. 40:379-387
Objectives: Matrix metalloproteinase-8 messenger RNA expression was previously found to be increased in whole blood of children with septic shock. The impact of this finding on the severity and inflammatory response to sepsis is unknown. Here, we inv
Autor:
Prajakta Mangeshkar, Patricia A. Abboud, Hector R. Wong, Michael O'Connor, Kelli Odoms, Timothy J. Burroughs, Paul W. Hake, Basilia Zingarelli
Publikováno v:
European Journal of Pharmacology. 579:411-417
Epigallocatechin-3-gallate (EGCG), a green tea catechin, has been shown to inhibit signaling pathways involved in inflammation, including nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1), which are important inducers of pro-inflammato
Autor:
Meena Kalyanaraman, Neal J. Thomas, Scott Penfil, Hector R. Wong, Natalie Z. Cvijanovich, Richard Lin, Bruce J. Aronow, Nancy M. Tofil, Michael R. Barnes, Marie Monaco, Thomas P. Shanley, Allan Doctor, Kelli Odoms, Geoffrey L. Allen, Bhuvaneswari Sakthivel
Publikováno v:
Molecular Medicine. 13:495-508
We have conducted longitudinal studies focused on the expression profiles of signaling pathways and gene networks in children with septic shock. Genome-level expression profiles were generated from whole blood-derived RNA of children with septic shoc
Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid
Autor:
Hector R. Wong, Ferdi Engels, Frank A. Redegeld, Kelli Odoms, Kathy Dunsmore, Esmaeil Mortaz, Frans P. Nijkamp
Publikováno v:
European Journal of Pharmacology. 561:214-219
Immunoglobulin (Ig) E-dependent activation of mast cells is central to the allergic response. The engagement of IgE-occupied receptors initiates a series of molecular events that causes the release of preformed, and de novo synthesis of, allergic med
Autor:
Hector R. Wong, Angela L. Morrison, Martin Dinges, Kristen D. Singleton, Kelli Odoms, Paul E. Wischmeyer
Publikováno v:
American Journal of Physiology-Cell Physiology. 290:C1625-C1632
Glutamine (GLN) has been shown to protect cells, tissues, and whole organisms from stress and injury. Enhanced expression of heat shock protein (HSP) has been hypothesized to be responsible for this protection. To date, there are no clear mechanistic
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 32:225-231
German cockroach extract synergistically regulates tumor necrosis factor-alpha (TNF-alpha)-induced interleukin (IL)-8 expression in human airway epithelial cells. The IL-8 promoter contains nuclear factor (NF)-kappaB, activating protein (AP)-1, and N
Autor:
John D. Catravas, Alvin Denenberg, Hector R. Wong, Kelli Odoms, Vivek Malhotra, Derek S. Wheeler
Publikováno v:
The Journal of Nutrition. 134:1039-1044
Polyphenolic components of green tea, such as epigallocatechin-3-gallate (EGCG), have potent anti-inflammatory properties. We previously showed that EGCG inhibits tumor necrosis factor-alpha (TNF-alpha)-mediated activation of the nuclear factor-kappa
Autor:
Edwin A. Deitch, E. Sylvester Vizi, Zoltán Németh, Csaba Szabó, Hector R. Wong, György Haskó, Kelli Odoms
Publikováno v:
Molecular Pharmacology. 65:342-349
The transcription factor nuclear factor kappaB (NF-kappaB) is activated and seems to promote oncogenesis in certain cancers. A major mechanism of NF-kappaB activation in cells involves cytoplasm-to-nucleus translocation of this transcription factor a
Publikováno v:
Shock. 17:274-279
Hyperoxia and tumor necrosis factor-alpha (TNFalpha) are two canonical signals centrally involved in the pathophysiology of acute lung injury. We have attempted to elucidate the effects of these two stimuli on the signal transduction pathways of lung
Autor:
Hector R. Wong, Thomas P. Shanley, Bruce J. Grossman, Kelli Odoms, Katherine E. Dunsmore, Alvin Denenberg
Publikováno v:
Inflammation. 26:129-137
Previous studies demonstrated important interactions between the heat shock response and the IκBα/NF-κB pathway when these two pathways are induced sequentially. One such interaction involves the ability of heat shock to inhibit subsequent degrada