Zobrazeno 1 - 10
of 3 056
pro vyhledávání: '"Kelley S"'
Autor:
Youngmin Hwang, Yuko Shimamura, Junichi Tanaka, Akihiro Miura, Anri Sawada, Hemanta Sarmah, Dai Shimizu, Yuri Kondo, Hyeonjeong Lee, Francesca Martini, Zurab Ninish, Kelley S. Yan, Kazuhiko Yamada, Munemasa Mori
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Mesothelial cells, in the outermost layer of internal organs, are essential for both organ development and homeostasis. Although the parietal mesothelial cell is the primary origin of mesothelioma that may highjack developmental signaling, the signal
Externí odkaz:
https://doaj.org/article/ba0a2b8b8e9045a7b7568d286481c4b9
Autor:
Zhengyu Jiang, Quin T. Waterbury, Ermanno Malagola, Na Fu, Woosook Kim, Yosuke Ochiai, Feijing Wu, Chandan Guha, Carrie J. Shawber, Kelley S. Yan, Timothy C. Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 321-346 (2024)
Background & Aims: The intestinal epithelium functions both in nutrient absorption and as a barrier, separating the luminal contents from a network of vascular, fibroblastic, and immune cells underneath. After injury to the intestine, multiple cell p
Externí odkaz:
https://doaj.org/article/55559053220146c28119bfea1537115d
Autor:
Kazuya Masuda, Adam Kornberg, Jonathan Miller, Sijie Lin, Nathan Suek, Theo Botella, Kerim A. Secener, Alyssa M. Bacarella, Liang Cheng, Matthew Ingham, Vilma Rosario, Ahmed M. Al-Mazrou, Steven A. Lee-Kong, Ravi P. Kiran, Marlon Stoeckius, Peter Smibert, Armando Del Portillo, Paul E. Oberstein, Peter A. Sims, Kelley S. Yan, Arnold Han
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Clinical outcomes in colorectal cancer (CRC) correlate with T cell infiltrates, but the specific contributions of heterogenous T cell types remain unclear. To investigate the diverse function of T cells in CRC, we profiled 37,931 T cells from tumors
Externí odkaz:
https://doaj.org/article/a994919d65984adfb8344af434a112be
Autor:
Moritz Middelhoff, Henrik Nienhüser, Giovanni Valenti, H. Carlo Maurer, Yoku Hayakawa, Ryota Takahashi, Woosook Kim, Zhengyu Jiang, Ermanno Malagola, Krystle Cuti, Yagnesh Tailor, Leah B. Zamechek, Bernhard W. Renz, Michael Quante, Kelley S. Yan, Timothy C. Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Acetylcholine regulates intestinal epithelial secretion via muscarinic Gq-coupled receptors but its role in cell differentiation is unclear. Here, the authors show that Prox1-positive endocrine cells are sensors for the cholinergic intestinal niche a
Externí odkaz:
https://doaj.org/article/7eeb82d636ca4537aa0b570f2e30840f
Autor:
Natacha Bohin, Kevin P. McGowan, Theresa M. Keeley, Elizabeth A. Carlson, Kelley S. Yan, Linda C. Samuelson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 797-810 (2020)
Background & Aims: Intestinal crypts have a remarkable capacity to regenerate after injury from loss of crypt base columnar (CBC) stem cells. After injury, facultative stem cells (FSCs) are activated to replenish the epithelium and replace lost CBCs.
Externí odkaz:
https://doaj.org/article/5de53985d03c4f63b42bc31b9a96944e
Autor:
Ryan P Dawes, Kathleen A Burke, Daniel K Byun, Zhou Xu, Petr Stastka, Leland Chan, Edward B Brown, Kelley S Madden
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 14 (2020)
Preclinical models of breast cancer have established mechanistic links between psychological stress and cancer progression. However, epidemiological evidence linking stress and cancer is equivocal. We tested the impact of stress exposure in female mi
Externí odkaz:
https://doaj.org/article/d4139f1831e34ef887c0debdfec2eac0
Autor:
Michael Koeppen, Jae W. Lee, Seong-Wook Seo, Kelley S. Brodsky, Simone Kreth, Ivana V. Yang, Peter M. Buttrick, Tobias Eckle, Holger K. Eltzschig
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Myocardial ischemia–reperfusion injury stabilizes the hypoxia-inducible factor HIF2-alpha. Here, the authors show that HIF2-alpha protects the heart from injury via induction of the epidermal growth factor amphiregulin, and that amphiregulin admini
Externí odkaz:
https://doaj.org/article/24c74b3146bb47afaae1377656aa4429
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2182 (2021)
The microbiome is an emerging key co-factor in the development of esophageal cancer, the sixth leading cause of cancer death worldwide. However, there is a paucity of data delineating how the microbiome contributes to the pathobiology of the two hist
Externí odkaz:
https://doaj.org/article/4d54caed2a3a4029b7bd59d588f1884c
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219914 (2019)
The complex three-way interaction between airflow, tissue, and sound, for asymmetric vocal fold vibration, is not well understood. Current modeling efforts are not able to explain clinical observations where drastic differences in sound production ar
Externí odkaz:
https://doaj.org/article/10e63ba6e17a4b31973723a7826c7ba4
Publikováno v:
Advanced Materials 2302120, 2023
Envisaging antiferromagnetic spintronics pivots on two key criteria of high transition temperature and tuning of underlying magnetic order using straightforward application of magnetic field or electric current. Here, we show that NiSi metal can prov
Externí odkaz:
http://arxiv.org/abs/2303.11387