Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Kelley Meade"'
Autor:
Eric M Wohlford, Luisa N Borrell, Jennifer R Elhawary, Brian Plotkin, Sam S Oh, Thomas J Nuckton, Celeste Eng, Sandra Salazar, Michael A LeNoir, Kelley Meade, Harold J Farber, Denise Serebrisky, Emerita Brigino-Buenaventura, William Rodriguez-Cintron, Rajesh Kumar, Shannon Thyne, Max A Seibold, José R Rodríguez-Santana, Esteban G Burchard
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0231782 (2020)
RationaleSevere early-life respiratory illnesses, particularly those caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV), are strongly associated with the development of asthma in children. Puerto Rican children in particular have
Externí odkaz:
https://doaj.org/article/9556ba7234fd4c1b8a9ec9bbf78f24e1
Autor:
Catarina D Campbell, Kiana Mohajeri, Maika Malig, Fereydoun Hormozdiari, Benjamin Nelson, Gaixin Du, Kristen M Patterson, Celeste Eng, Dara G Torgerson, Donglei Hu, Catherine Herman, Jessica X Chong, Arthur Ko, Brian J O'Roak, Niklas Krumm, Laura Vives, Choli Lee, Lindsey A Roth, William Rodriguez-Cintron, Jose Rodriguez-Santana, Emerita Brigino-Buenaventura, Adam Davis, Kelley Meade, Michael A LeNoir, Shannon Thyne, Daniel J Jackson, James E Gern, Robert F Lemanske, Jay Shendure, Mark Abney, Esteban G Burchard, Carole Ober, Evan E Eichler
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104396 (2014)
Asthma is a complex genetic disease caused by a combination of genetic and environmental risk factors. We sought to test classes of genetic variants largely missed by genome-wide association studies (GWAS), including copy number variants (CNVs) and l
Externí odkaz:
https://doaj.org/article/98e7e72d10cd4b5ca2e3cbed7c9bd96a
Autor:
William Rodriguez-Cintron, Shannon Thyne, Thomas J. Nuckton, Lesly Anne Samedy-Bates, Jennifer R. Elhawary, Luisa N. Borrell, Kelley Meade, Maria Pino-Yanes, Celeste Eng, Jose R. Rodriguez-Santana, Sam S. Oh, Andrew M. Zeiger, Rajesh Kumar, Emerita Brigino-Buenaventura, Sandra Salazar, Kirsten Bibbins-Domingo, Marquitta J. White, Harold J. Farber, Tyronda Elliot, Esteban G. Burchard, Denise Serebrisky, Michael A. LeNoir
Publikováno v:
Clin Pharmacol Ther
Clinical pharmacology and therapeutics, vol 106, iss 5
Clinical pharmacology and therapeutics, vol 106, iss 5
American Thoracic Society guidelines recommend inhaled corticosteroid (ICS) therapy, plus a short-acting bronchodilator, in patients with persistent asthma. However, few prior studies have examined the efficacy of this combination in children of all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091cf05a865ecb17279702d7fd2bb70
https://doi.org/10.1002/cpt.1555
https://doi.org/10.1002/cpt.1555
Autor:
Dan L. Nicolae, Pedro C. Avila, Badri Padhukasahasram, Eugene R. Bleecker, W. James Gauderman, Carole Ober, Lindsey A. Roth, Cheryl A. Winkler, Luisa N. Borrell, Meghan E. McGarry, Sam S. Oh, Neeta Thakur, Esteban G. Burchard, Blanca Estela Del Río-Navarro, Jose R. Rodriguez-Santana, Isabelle Romieu, Emerita Brigino-Buenaventura, David V. Conti, Joshua Galanter, Benjamin A. Raby, Frank D. Gilliland, Albert M. Levin, Carlos Bustamante, Maria Pino-Yanes, Dara G. Torgerson, Kathleen C. Barnes, William Rodriguez-Cintron, Scott T. Weiss, Christopher R. Gignoux, Ryan D. Hernandez, Andrés Moreno-Estrada, Stephanie J. London, Scott Huntsman, Elizabeth A. Nguyen, Weiniu Gan, Fernando J. Martinez, Max A. Seibold, Lawrence H. Uricchio, Shannon Thyne, Saunak Sen, Celeste Eng, Harold J. Farber, L. Keoki Williams, Karla Sandoval, Juan José Luis Sienra-Monge, Deborah A. Meyers, Donglei Hu, Kelley Meade, Michael A. LeNoir, Bonnie R. Joubert, Rasika A. Mathias, Denise Serebrisky, Rajesh Kumar
Publikováno v:
The Journal of allergy and clinical immunology, vol 143, iss 3
BackgroundAsthma is a common but complex disease with racial/ethnic differences in prevalence, morbidity, and response to therapies.ObjectiveWe sought to perform an analysis of genetic ancestry to identify new loci that contribute to asthma susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530c80fca046104777703d8f39332e3e
https://doi.org/10.1016/j.jaci.2016.08.057
https://doi.org/10.1016/j.jaci.2016.08.057
Autor:
Rajesh Kumar, Meghan E. McGarry, Pedro C. Avila, Shannon Thyne, Ryan D. Hernandez, Max A. Seibold, Dara G. Torgerson, Jean G. Ford, Jose R. Rodriguez-Santana, Maria Pino-Yanes, Melissa L. Spear, Rocio Chapela, Donglei Hu, Neeta Thakur, Joshua Galanter, Angel C.Y. Mak, Adam Davis, Deborah A. Myers, Marquitta J. White, Celeste Eng, L. Keoki Williams, Emerita Brigino-Buenaventura, Albert M. Levin, Harold J. Farber, Eugene R. Bleecker, Stephen P. Peters, Andres Moreno Estrada, Denise Serebrisky, Scott Huntsman, Esteban G. Burchard, Sam S. Oh, Victor E. Ortega, Kelley Meade, William Rodriguez Cintron, Elizabeth J. Ampleford, Cheryl A. Winkler, Karla Sandoval, Michael A. LeNoir
Publikováno v:
The pharmacogenomics journal, vol 19, iss 3
The pharmacogenomics journal
The pharmacogenomics journal
Short-acting β2-adrenergic receptor agonists (SABAs) are the most commonly prescribed asthma medications worldwide. Response to SABAs is measured as bronchodilator drug response (BDR), which varies among racial/ethnic groups in the United States. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5735cbcd8920e06a2d49cfb8a66d97a
https://doi.org/10.1038/s41397-018-0042-4
https://doi.org/10.1038/s41397-018-0042-4
Autor:
Ann Chen Wu, Sandra Salazar, Paǵe Goddard, Zachary A. Szpiech, Karla Sandoval, Scott Huntsman, Kevin L. Keys, Pui-Yan Kwok, Andrés Moreno-Estrada, Esteban G. Burchard, Kelley Meade, Marquitta J. White, Soren Germer, Noah Zaitlen, Rajesh Kumar, Walter L. Eckalbar, Erick Forno, Albert M. Levin, Robert B. Darnell, Celeste Eng, Karen L. Bunting, L. Keoki Williams, Emerita Brigino-Buenaventura, Patrick M. A. Sleiman, Shannon Thyne, Thomas J. Nuckton, Jose R. Rodriguez-Santana, Maria Pino-Yanes, Amber Dahlin, Thomas A. Nguyen, Michael A. LeNoir, Dara G. Torgerson, Donglei Hu, William Rodriguez-Cintron, Cheryl A. Winkler, Jennifer Liberto, Joshua Galanter, Angel C.Y. Mak, Max A. Seibold, Pedro C. Avila, Denise Serebrisky, Scott T. Weiss, Julia M. Vogel, Sam S. Oh, Hakon Hakonarson, Juan C. Celedón, Blanca E. Himes, Nadav Ahituv, Ryan D. Hernandez, Elad Ziv, Saunak Sen, Harold J. Farber, Kelan G. Tantisira
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:1552-1564
Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide. There are significant racial/ethnic differences in albuterol drug response. Objectives: To identify genetic variants important for bronchodilator drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb21ff0c6ecd75de255d15ebc153cdb2
https://doi.org/10.1164/rccm.201712-2529oc
https://doi.org/10.1164/rccm.201712-2529oc
Differential asthma risk following respiratory infection in children from three minority populations
Autor:
Thomas J. Nuckton, Max A. Seibold, William Rodriguez-Cintron, Esteban G. Burchard, Shannon Thyne, Celeste Eng, Denise Serebrisky, Emerita Brigino-Buenaventura, Michael A. LeNoir, Kelley Meade, Jose R. Rodriguez-Santana, Brian Plotkin, Eric M. Wohlford, Sam S. Oh, Luisa N. Borrell, Jennifer R. Elhawary, Sandra Salazar, Harold J. Farber, Rajesh Kumar
RationaleSevere early-life respiratory illnesses, particularly those caused by respiratory syncytial virus (RSV) and human rhinovirus (HRV), are strongly associated with the development of asthma in children. Puerto Rican children in particular have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6351c6ff826f954b5d4243787d32595f
https://doi.org/10.1101/19011528
https://doi.org/10.1101/19011528
Autor:
Angel C.Y. Mak, Sandra Salazar, Fred Lurmann, Marquitta J. White, Andrew M. Zeiger, Michael A. LeNoir, Sam S. Oh, Ellen A. Eisen, Thomas J. Nuckton, Donglei Hu, John R. Balmes, Luisa N. Borrell, Maria G. Contreras, Adam Davis, Pagé C. Goddard, Emerita N. Brigino-Buenaventura, Lesly-Anne Samedy, Eunice Y. Lee, Esteban G. Burchard, Celeste Eng, Scott Huntsman, Kelley Meade, Kevin L. Keys, Jennifer R. Elhawary
Publikováno v:
The Journal of allergy and clinical immunology, vol 144, iss 3
J Allergy Clin Immunol
J Allergy Clin Immunol
BACKGROUND: Telomere length (TL) can serve as a potential biomarker for conditions associated with chronic oxidative stress and inflammation, such as asthma. Air pollution can induce oxidative stress. Understanding the relationship between TL, asthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89eb02172cbfccde33e93fe3e8cb790e
https://escholarship.org/uc/item/1135620s
https://escholarship.org/uc/item/1135620s
Autor:
Amy P. Hardin, Alexy Arauz Boudreau, Jesse M. Hackell, Scot Moore, Joseph J. Abularrage, Yvette M. Almendarez, Alex R. Kemper, Julia E. Richerson, Joseph F. Hagan, Patricia E. Cantrell, Judith S. Shaw, Robin Warner, Kelley Meade
Publikováno v:
Pediatrics. 143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92beec59574539595460cfe79f19e798
https://doi.org/10.1542/peds.2018-3971
https://doi.org/10.1542/peds.2018-3971
Autor:
Adam Davis, Ellen A. Eisen, Max A. Seibold, Marquitta J. White, W. James Gauderman, Rajesh Kumar, Shannon Thyne, Neeta Thakur, Emerita Brigino-Buenaventura, Donglei Hu, Elizabeth A. Nguyen, Dara G. Torgerson, Angel C.Y. Mak, Jose R. Rodriguez-Santana, Katherine K. Nishimura, Esteban G. Burchard, Pedro C. Avila, Joshua Galanter, Michael A. LeNoir, Andreas M. Neophytou, Denise Serebrisky, Maria Pino-Yanes, Fred Lurmann, Saunak Sen, Sam S. Oh, Harold J. Farber, William Rodriguez-Cintron, John R. Balmes, Christopher R. Gignoux, Frank D. Gilliland, Celeste Eng, L. Keoki Williams, Kelley Meade, Kirsten Bibbins-Domingo
Publikováno v:
American journal of respiratory and critical care medicine, vol 193, iss 11
RationaleAdverse effects of exposures to ambient air pollution on lung function are well documented, but evidence in racial/ethnic minority children is lacking.ObjectivesTo assess the relationship between air pollution and lung function in minority c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff247255034390e7731565ae9fff6ec
https://doi.org/10.1164/rccm.201508-1706oc
https://doi.org/10.1164/rccm.201508-1706oc