Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kelley L. Morse"'
Autor:
Xudong Qiao, Ling Pang, Suke Wang, Joseph A. Hedrick, Frederick J. Monsma, Kelley L. Morse, Thomas M. Laz, LiXin Shan, Marvin L. Bayne, Eric L. Gustafson
Publikováno v:
Molecular Pharmacology. 58:870-875
Neuromedin U (NmU) is a 25 amino acid peptide prominently expressed in the upper gastrointestinal (GI) tract and central nervous system. It is highly conserved throughout evolution and induces smooth muscle contraction in a variety of species. Our un
Autor:
Marvin L. Bayne, Elizabeth Coates, Kelley L. Morse, Nicholas J. Murgolo, Niu Shin, Frederick J. Monsma, Catherine D. Strader
Publikováno v:
Molecular pharmacology. 62(1)
The histamine H4 receptor is a novel G-protein-coupled receptor with a unique pharmacological profile. The distribution of H4 mRNA suggests that it may play a role in the regulation of immune function, particularly with respect to allergy and asthma.
Autor:
Wen-Jeng Yao, Beth E. Borowsky, Dhanapalan Nagarathnam, Mary C. Johnson, Kelley L. Morse, John Salon, Douglas A. Craig, Quanrong Shen, Joe A. Tamm, Caryn A Gunwaldsen, Thomas M. Laz, Kenneth A. Jones, Ling-Yan Huang, Cheng Tang, Christophe P. G. Gerald, Theresa Branchek, Meng Dai, Kelli E. Smith, Stewart A. Noble, Margaret M. Durkin
Publikováno v:
Nature. 396(6712)
The principal inhibitory neurotransmitter GABA (gamma-aminobutyric acid) exerts its effects through two ligand-gated channels, GABA(A) and GABA(C) receptors, and a third receptor, GABA(B) , which acts through G proteins to regulate potassium and calc
Publikováno v:
Life sciences. 56(23-24)
In order to explore the structural requirements for cannabinoid activity we have been involved in the design and synthesis of stereochemically defined high affinity probes for the cannabinoid receptor. This effort has involved the development of irre