Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kelley E, Sanok"'
Autor:
Susan D. O'Lone, Maria Engel, Ronald D. Fiedler, Maik Schuler, Kelley E. Sanok, Krista L. Dobo, Catherine J. Thiffeault, Stephanie L. Coffing, Donna A. Dickinson, William C. Gunther, Thomas J. Shutsky
Publikováno v:
Environmental and Molecular Mutagenesis. 55:492-499
Ethyl methanesulfonate (EMS) was evaluated as part of the validation effort for the rat Pig-a mutation assay and compared with other well-established in vivo genotoxicity endpoints. Male Sprague-Dawley (SD) rats were given a daily dose of 0, 6.25, 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0f71d6e3dccac49af2f77952153c43
https://doi.org/10.1002/em.21863
https://doi.org/10.1002/em.21863
Autor:
Susan D. O'Lone, Krista L. Dobo, William C. Gunther, Richard A. Spellman, Maik Schuler, Paula A. Muehlbauer, Claudia J. Wiersch, Kelley E. Sanok
Publikováno v:
Environmental and Molecular Mutagenesis. 49:318-327
Previously, this laboratory reported on the development of a flow cytometry-based method that automates the assessment of the mitotic index (MI) and numerical chromosome changes in chemically treated cultures of human lymphocytes [Muehlbauer PA and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc8bcb9461ba3a6384307a40add0dfa
https://doi.org/10.1002/em.20387
https://doi.org/10.1002/em.20387
Autor:
William C, Gunther, Stephanie L, Coffing, Donna A, Dickinson, Maria E, Engel, Ronald D, Fiedler, Susan D, O'Lone, Kelley E, Sanok, Catherine J, Thiffeault, Thomas J, Shutsky, Maik J, Schuler, Krista L, Dobo
Publikováno v:
Environmental and molecular mutagenesis. 55(6)
Ethyl methanesulfonate (EMS) was evaluated as part of the validation effort for the rat Pig-a mutation assay and compared with other well-established in vivo genotoxicity endpoints. Male Sprague-Dawley (SD) rats were given a daily dose of 0, 6.25, 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f283fe0fbef317707abfa4b5e8cf0816
https://pubmed.ncbi.nlm.nih.gov/24599777
https://pubmed.ncbi.nlm.nih.gov/24599777
Autor:
Stephanie L. Coffing, Andrew D. Scott, Richard A. Spellman, Michael Homiski, Krista L. Dobo, Donna A. Dickinson, Jennifer B. Munzner, Kelley E. Sanok, Maik Schuler, Jennifer R. Cheung, William C. Gunther, Dingzhou Li, Zhanna Sobol
Publikováno v:
Mutation research. 746(1)
The Organization for Economic Co-operation and Development (OECD) has recently adopted Test Guideline 487 (TG487) for conducting the in vitro micronucleus (MNvit) assay. The purpose of this study is to evaluate and validate treatment conditions for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3681288ca9cc18d8ecb2375d58002d
https://pubmed.ncbi.nlm.nih.gov/22445949
https://pubmed.ncbi.nlm.nih.gov/22445949
Autor:
Leon F. Stankowski, Richard A. Spellman, M. Chan, Ajit K. Thakur, D. J. Roberts, H. Chen, G. L. DeVito, H. Murli, Kelley E. Sanok, P. Yurt
Publikováno v:
Environmental and molecular mutagenesis. 53(4)
A flow cytometric procedure for determining mitotic index (MI) as part of the metaphase chromosome aberrations assay, developed and utilized routinely at Pfizer as part of their standard assay design, has been adopted successfully by Covance laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ac22158264a2883ffd9195cd0cdd76
https://pubmed.ncbi.nlm.nih.gov/22351437
https://pubmed.ncbi.nlm.nih.gov/22351437