Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kelley Carr"'
Autor:
Krystel El Hage, Nelson B. Phillips, Yen-Shan Chen, Balamurugan Dhayalan, Jonathan Whittaker, Kelley Carr, Linda Whittaker, Manijeh H. Phillips, Faramarz Ismail-Beigi, Markus Meuwly, Michael A. Weiss
The utility of halogenation in protein design is investigated by a combination of quantitative atomistic simulations and experiment. The approach is applied to insulin, a small, therapeutically relevant domain amenable to simulation and semi-synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b5e6bc8c26a2edb3296decfd2c8a1d
https://doi.org/10.1101/2022.07.25.501420
https://doi.org/10.1101/2022.07.25.501420
Autor:
Nelson B. Phillips, Xun Gong, Michael S. Strano, Naveed A. Bakh, Kelley Carr, Michael A. Weiss, Faramarz Ismail-Beigi, Jing Fan Yang
Publikováno v:
Diabetes. 69:1815-1826
Despite considerable progress, development of glucose-responsive insulins (GRIs) still largely depends on empirical knowledge and tedious experimentation—especially on rodents. To assist the rational design and clinical translation of the therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e7d38ca99ec533ae8e1941a237fef3
https://doi.org/10.2337/db19-0879
https://doi.org/10.2337/db19-0879
Autor:
Brian J. Smith, Nalinda P. Wickramasinghe, Faramarz Ismail-Beigi, Yanwu Yang, Michael D. Glidden, Nelson B. Phillips, Michael A. Weiss, Nicholas A. Smith, Michael C. Lawrence, Kelley Carr
Publikováno v:
Journal of Biological Chemistry. 293:69-88
Domain-minimized insulin receptors (IRs) have enabled crystallographic analysis of insulin-bound “micro-receptors.” In such structures, the C-terminal segment of the insulin B chain inserts between conserved IR domains, unmasking an invariant rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569973edffa629e3c89a3ae3b60b4316
https://doi.org/10.1074/jbc.m117.808667
https://doi.org/10.1074/jbc.m117.808667
Autor:
Michael C. Lawrence, Manijeh Phillips, Nalinda P. Wickramasinghe, Faramarz Ismail-Beigi, Nelson B. Phillips, Jonathan Whittaker, Kelley Carr, Michael D. Glidden, Yanwu Yang, Khadijah Aldabbagh, Nischay Rege, Yen Shan Chen, Michael A. Weiss, Mamuni Swain, Yi Peng, Vivien C. Yee
Thermal degradation of insulin complicates its delivery and use. Previous efforts to engineer ultra-stable analogs were confounded by prolonged cellular signaling in vivo, of unclear safety and complicating mealtime therapy. We therefore sought an ul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f08dc8ce4ba088ce3c8e664fec15372
https://europepmc.org/articles/PMC5766902/
https://europepmc.org/articles/PMC5766902/
Autor:
Paul E. Draper, Leonard T. Campi, Robert J. Maass, David L. Hall, Charles J. Sabel, W. Kelley Carr
Publikováno v:
The Journal of the American Dental Association. 66:413-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef3b6a7f37779d4d02209bb8831d698
https://doi.org/10.14219/jada.archive.1963.0115
https://doi.org/10.14219/jada.archive.1963.0115
Publikováno v:
Case Reports in Radiology, Vol 2017 (2017)
Ectopic thyroid tissue is a rare entity and when discovered it is typically along the pathway of embryologic migration of the thyroid. We present a case of incidental finding of ectopic thyroid tissue within mediastinum in a 61-year-old female patien
Externí odkaz:
https://doaj.org/article/1f29d82803074be6be13d992dfb72ab2
Autor:
Kelley Carr, W., Sabel, Charles J., Hall, David L., Campi, Leonard T., Draper, Paul E., Maass, Robert J.
Publikováno v:
Journal of the American Dental Association; March 1963, Vol. 66 Issue: 3 p413-416, 4p
Autor:
W. Kelley Carr
Publikováno v:
The Journal of the American Dental Association. 89:1251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7c41316055e839066c1d0beb327b5c4
https://doi.org/10.14219/jada.archive.1974.0624
https://doi.org/10.14219/jada.archive.1974.0624