Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kelley C. Larson"'
Autor:
Kelley C. Larson, Lauren H. Martens, Michael Marconi, Christopher Dejesus, Suzanne Bruhn, Thomas A. Miller, Barbara Tate, Jonathan M. Levenson
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Neuroinflammation is a key driver of neurodegenerative disease, however the tools available to model this disease biology at the systems level are lacking. We describe a translational drug discovery platform based on organotypic culture of m
Externí odkaz:
https://doaj.org/article/f99fd718d187495393c0c52cd3dd9f64
Autor:
Kelley C. Larson, Frederick Gergits, Daria Tchessalova, Abigail Renoux, Matthew Figley, Richard Fisher, Spyros Papapetropoulos, Christian Mirescu
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Jeffrey R. Cottrell, Pascal Laeng, Jianping Song, Kelley C. Larson, Jonathan M. Levenson, Crystle J. Ashford, Betty Chan, David J. Gerber, Bing Li
Publikováno v:
SLAS Discovery. 19:205-214
Alterations in synaptic transmission have been implicated in a number of psychiatric and neurological disorders. The discovery of small-molecule modulators of proteins that regulate neurotransmission represents a novel therapeutic strategy for these
Autor:
Jermaine Ross, Kelley C. Larson, Sarah Kolitz, Thomas A. Miller, Michael Marconi, Matthew Ung, Barbara Tate, Jonathan M. Levenson, Lauren H. Martens, Rebecca Kusko, Rob Nunes, Ben Zeskind, Christopher D. Dejesus
Publikováno v:
Alzheimer's & Dementia. 15:P947-P947
Autor:
Kevin A. Klausner, Mark L. Nelson, Aleksandrs Odinecs, Raina G. Leahy, Atul K. Verma, Jiri Gut, Ann B. Macone, Philip J. Rosenthal, Michael Draper, Laura Honeyman, Beena Bhatia, J. Donatelli, Haregewein Assefa, Lynne Garrity-Ryan, Kelley C. Larson, Kwasi Ohemeng
Publikováno v:
Antimicrobial agents and chemotherapy, vol 57, iss 7
With increasing resistance to existing antimalarials, there is an urgent need to discover new drugs at affordable prices for countries in which malaria is endemic. One approach to the development of new antimalarial drugs is to improve upon existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83513ff5d2948fedf4ad2881820e60c4
https://europepmc.org/articles/PMC3697387/
https://europepmc.org/articles/PMC3697387/
Autor:
Michael P. Draper, Ying Hsiu Liu, Paul Higgins, Jason Edmonds, Francine M. Jodelka, Kelley C. Larson, Adrian R. Krainer, Mark L. Nelson, Todd Bowser, Sujatha Kumar, Joel Berniac, Paul Abato, Michelle L. Hastings, Caroline Dudley, Lea Barthel
Publikováno v:
Science Translational Medicine. 1
There is at present no cure or effective therapy for spinal muscular atrophy (SMA), a neurodegenerative disease that is the leading genetic cause of infant mortality. SMA usually results from loss of the SMN1 (survival of motor neuron 1) gene, which
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 59(1)
Inflammation plays a central role in many neurodegenerative diseases, including Parkinson's, Alzheimer's, multiple sclerosis, amyotrophic lateral sclerosis, and AIDS dementia. Microglia are the resident macrophages of the central nervous system and a