Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kelley C. Atkinson"'
Autor:
Maria T. Sekyi, Micah Feri, Shane Desfor, Kelley C. Atkinson, Batis Golestany, Fernando Beltran, Seema K. Tiwari-Woodruff
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Impaired visual function is a prevalent feature of optic neuritis (ON) in multiple sclerosis (MS). Abnormal visual evoked potential (VEP) findings of increased latencies, reduced amplitudes and abnormal waveforms as well as decreased retinal
Externí odkaz:
https://doaj.org/article/29646ae07702466fa0ae2e8dc2aefbc8
The complexities of investigating mitochondria dynamics in multiple sclerosis and mouse models of MS
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Multiple sclerosis (MS) is a demyelinating, degenerating disorder of the central nervous system (CNS) that is accompanied by mitochondria energy production failure. A loss of myelin paired with a deficit in energy production can contribute to further
Externí odkaz:
https://doaj.org/article/269d71065d644ea6af22fc5e7703a911
Autor:
Jeffrey L. Dupree, Pablo M. Paez, Seema K. Tiwari-Woodruff, Travis T. Denton, Kenneth Hensley, Christina G. Angeliu, Anne I. Boullerne, Sergey Kalinin, Sophia Egge, Veronica T. Cheli, Giancarlo Denaroso, Kelley C. Atkinson, Micah Feri, Douglas L. Feinstein
Publikováno v:
ASN Neuro, Vol 14 (2022)
Although over 20 disease modifying therapies are approved to treat Multiple Sclerosis (MS), these do not increase remyelination of demyelinated axons or mitigate axon damage. Previous studies showed that lanthionine ketenamine ethyl ester (LKE) reduc
Externí odkaz:
https://doaj.org/article/3641087f2b974803ace5d745e6ad5564
Autor:
Kelley C. Atkinson, Jeong Bin Lee, Jonathan P.C. Hasselmann, Sung Hoon Kim, Alyson Drew, Joselyn Soto, John A. Katzenellenbogen, Neil G. Harris, Andre Obenaus, Seema K. Tiwari-Woodruff
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104501- (2019)
Diffusion tensor imaging (DTI) has been shown to detect white matter degeneration in multiple sclerosis (MS), a neurodegenerative autoimmune disease that presents with diffuse demyelination of the central nervous system. However, the utility of DTI i
Externí odkaz:
https://doaj.org/article/c39012fcdc2f4374ae3f095ada06d640
Autor:
Kelli Lauderdale, Kelley C. Atkinson, Batis Golestany, Micah Feri, Hawra Karim, Steven Nusinowitz, Marianne Cilluffo, Sung Hoon Kim, Seema K. Tiwari-Woodruff, Maria Sekyi, Cobi Diaz, John A. Katzenellenbogen, Joselyn Soto
Publikováno v:
Brain Pathology
Visual deficits are among the most prevalent symptoms in patients with multiple sclerosis (MS). To understand deficits in the visual pathway during MS and potential treatment effects, we used experimental autoimmune encephalomyelitis (EAE), the most
Autor:
Alyson Drew, Neil G. Harris, John A. Katzenellenbogen, Jonathan Hasselmann, Sung Hoon Kim, Seema K. Tiwari-Woodruff, Jeong Bin Lee, Kelley C. Atkinson, Andre Obenaus, Joselyn Soto
Publikováno v:
Neurobiology of Disease, Vol 130, Iss, Pp 104501-(2019)
Neurobiol Dis
Neurobiol Dis
Diffusion tensor imaging (DTI) has been shown to detect white matter degeneration in multiple sclerosis (MS), a neurodegenerative autoimmune disease that presents with diffuse demyelination of the central nervous system. However, the utility of DTI i
Autor:
John A. Katzenellenbogen, Kelli Lauderdale, Hana Yamate-Morgan, Sung Hoon Kim, Hawra Karim, Kelley C. Atkinson, Norio Yasui, Andrew Lapato, Maria Sekyi, Seema K. Tiwari-Woodruff
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports
Pharmaceutical agents currently approved for the treatment of multiple sclerosis reduce relapse rates, but do not reverse or prevent neurodegeneration nor initiate myelin repair. The highly selective estrogen receptor (ER) β ligand chloroindazole (I