Identifying hypothetical genetic influences on complex disease phenotypes

Autor: Keller Benjamin J, McEachin Richard C

Publikováno v: BMC Bioinformatics, Vol 10, Iss Suppl 2, p S13 (2009)

Abstract Background Statistical interactions between disease-associated loci of complex genetic diseases suggest that genes from these regions are involved in a common mechanism impacting, or impacted by, the disease. The computational problem we add

Externí odkaz: https://doaj.org/article/fa4076b528874cf9a9e914ccd463e5e8

When being Weak is Brave: Privacy in Recommender Systems

Autor: Ramakrishnan, Naren, Keller, Benjamin J., Mirza, Batul J., Grama, Ananth Y., Karypis, George

We explore the conflict between personalization and privacy that arises from the existence of weak ties. A weak tie is an unexpected connection that provides serendipitous recommendations. However, information about weak ties could be used in conjunc

Externí odkaz: http://arxiv.org/abs/cs/0105028

A systems view of genetics in chronic kidney disease

Autor: Keller, Benjamin J., Martini, Sebastian, Sedor, John R., Kretzler, Matthias ^*

Publikováno v: In Kidney International 1 January 2012 81(1):14-21

Genetic studies of body mass index yield new insights for obesity biology

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Nature, 518(7538), 197. Nature Publishing Group
Nature
Nature, 518(7538), 197-U401
Nature, Vol. 518, No 7538 (2015) pp. 197-206
Nature, vol. 518, no. 7538, pp. 197-206
Nature 518(7538), 197-206 (2015). doi:10.1038/nature14177
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Locke, A E, Kahali, B, Berndt, S I, Justice, A E, Pers, T H, Day, F R, Powell, C, Vedantam, S, Buchkovich, M L, Yang, J, Croteau-Chonka, D C, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, J C, Winkler, T W, Wood, A R, Workalemahu, T, Faul, J D, Smith, J A, Zhao, J H, Zhao, W, Chen, J, Fehrmann, R, Hedman, A K, Karjalainen, J, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M & Bolton, J L & Bragg-Gresham, L & Buyske, S & Demirkan, A & Deng, G & Fraser, R M & Hayward, C & McLachlan, S & Campbell, H & Morris, A D & Price, J F & Rudan, I & Walker, M & Wilson, J F & Visscher, P M 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-U401 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197-U401. Nature Publishing Group
Nature, 518, 7538, pp. 197-206
Nature, 518, 197-206

Item does not contain fulltext Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure

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https://research.vu.nl/en/publications/58992b26-1689-48dd-bb82-82548598fe61

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