Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kellee F. Greene"'
Autor:
Craig M. Brackett, Kellee F. Greene, Alyssa R. Aldrich, Nicholas H. Trageser, Srabani Pal, Ivan Molodtsov, Bojidar M. Kandar, Lyudmila G. Burdelya, Scott I. Abrams, Andrei V. Gudkov
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Acute radiation syndrome (ARS) is a major cause of lethality following radiation disasters. A TLR5 agonist, entolimod, is among the most powerful experimental radiation countermeasures and shows efficacy in rodents and non-human primates as
Externí odkaz:
https://doaj.org/article/b4c8b20a57ee4a1e98fe58a3cedda4f2
Autor:
Natalia Fedtsova, Elena A. Komarova, Kellee F. Greene, Liliya R. Novototskaya, Ivan Molodtsov, Craig M. Brackett, Evguenia Strom, Anatoli S. Gleiberman, Alexander N. Shakhov, Andrei V. Gudkov
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Abstract Transplantation of bone marrow (BM) is made possible by the differential sensitivity of its stromal and hematopoietic components to preconditioning by radiation and/or chemotherapeutic drugs. These genotoxic treatments eliminate host hematop
Externí odkaz:
https://doaj.org/article/567e32f8c63e48f8b13d02edbbb27399
Autor:
Lyudmila G. Burdelya, Craig M. Brackett, Kellee F. Greene, Alyssa R Aldrich, Andrei V. Gudkov, Scott I. Abrams, Nicholas H Trageser, Ivan Molodtsov, Srabani Pal, Bojidar M. Kandar
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Acute radiation syndrome (ARS) is a major cause of lethality following radiation disasters. A TLR5 agonist, entolimod, is among the most powerful experimental radiation countermeasures and shows efficacy in rodents and non-human primates as a prophyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4b142784726a4dfddc9744b6fcd7c2
https://pubmed.ncbi.nlm.nih.gov/34584068
https://pubmed.ncbi.nlm.nih.gov/34584068
Autor:
Kellee F. Greene, Anatoli S. Gleiberman, Alexander N. Shakhov, Elena A. Komarova, Natalia Fedtsova, Evguenia Strom, Craig M. Brackett, Andrei V. Gudkov, Ivan Molodtsov, Liliya R. Novototskaya
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Transplantation of bone marrow (BM) is made possible by the differential sensitivity of its stromal and hematopoietic components to preconditioning by radiation and/or chemotherapeutic drugs. These genotoxic treatments eliminate host hematopoietic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73009fdcba6cd3a55b4d5176715b514e
http://europepmc.org/articles/PMC8154997
http://europepmc.org/articles/PMC8154997
Autor:
Craig M Brackett, Alyssa R Aldrich, Kellee F Greene, Bojidar Kandar, Jean Veith, Lyudmila G Burdelya, Scott I. Abrams, Andrei V Gudkov
Publikováno v:
Cancer Research. 82:P4-04
Triple-negative breast cancer (TNBC) accounts for 15-20% of all breast cancer diagnoses, is the most aggressive form of the disease, and has the poorest clinical outcomes. Effective or durable therapies are lacking because these tumors lack targets f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da0f0fc4ffd7347aebd50887b921745
https://doi.org/10.1158/1538-7445.sabcs21-p4-04-02
https://doi.org/10.1158/1538-7445.sabcs21-p4-04-02
Autor:
Elena A. Komarova, Ellen Karasik, Bryan Gillard, Anatoly S. Gleiberman, M Bapardekar-Nair, Oleg V. Kurnasov, Semra Aygun-Sunar, Christopher Johnson, Vadim L. Mett, Andrei L. Osterman, Andrei V. Gudkov, Carl Morrison, Ivan A. Bespalov, Ilya Toshkov, Craig M. Brackett, Kellee F. Greene, Barbara A. Foster, Patricia Stanhope-Baker, Michael T. Moser
Publikováno v:
Oncogene
Toll-like receptor 5 (TLR5) is considered an attractive target for anticancer immunotherapy. TLR5 agonists, bacterial flagellin and engineered flagellin derivatives, have been shown to have potent antitumor and metastasis-suppressive effects in multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f554da51ebc5120ef78dfc73b88db3e8
https://doi.org/10.1038/onc.2017.346
https://doi.org/10.1038/onc.2017.346
Autor:
Sandra O. Gollnick, Bojidar Kojouharov, Kellee F. Greene, Craig M. Brackett, Jean Veith, Andrei V. Gudkov, Lyudmila G. Burdelya, Scott I. Abrams
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Activation of an anticancer innate immune response is highly desirable because of its inherent ability to generate an adaptive antitumor T-cell response. However, insufficient safety of innate immune modulators limits clinical use to topical applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5d60f6c65d6cf3b72697f8e89f841a
https://doi.org/10.1073/pnas.1521359113
https://doi.org/10.1073/pnas.1521359113
Autor:
Jean B. Dawidzik, Han-Chun DeFedericis, Edwin E. Budzinski, Harold C. Box, Douglas T. Bailey, Herbert Iijima, Kellee F. Greene, Harold G. Freund, Marianne S. Evans, Helen B. Patrzyc
Publikováno v:
Radiation Research. 167:146-151
UVC-radiation-induced DNA damage was measured in mouse fibroblast cells using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in conjunction with isotopically labeled internal standards. The thymine glycol and formamide lesions were assayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adfccee0cd5be2a49fdb65511fadaac
https://doi.org/10.1667/rr0693.1
https://doi.org/10.1667/rr0693.1
Autor:
Han-Chun DeFedericis, Jean B. Dawidzik, Edwin E. Budzinski, Marianne S. Evans, Helen B. Patrzyc, Kellee F. Greene, Michael J. Rajecki, Harold C. Box, Herbert Iijima
Publikováno v:
Radiation Research. 165:445-451
Singlet oxygen, hydrogen peroxide, hydroxyl radical and hydrogen peroxide are the reactive oxygen species (ROS) considered most responsible for producing oxidative stress in cells and organisms. Singlet oxygen interacts preferentially with guanine to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09684d616f893b84fe0ce93bb1d0791
https://doi.org/10.1667/rr3533.1
https://doi.org/10.1667/rr3533.1
Autor:
Jean B. Dawidzik, Harold C. Box, Helen B. Patrzyc, Douglas T. Bailey, Han-Chun DeFedericis, Kellee F. Greene, Herbert Iijima, Edwin E. Budzinski
Publikováno v:
Radiation research. 165(4)
A different approach to the measurement of DNA damage has been developed based on the fact that many lesions can be excised from DNA in the form of modified dinucleoside monophosphates. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e5884267db0e51fe9f90a372e44ed0
https://pubmed.ncbi.nlm.nih.gov/16579656
https://pubmed.ncbi.nlm.nih.gov/16579656