Innate Immunity to Orthohantaviruses: Could Divergent Immune Interactions Explain Host-specific Disease Outcomes?

Autor: Kell AM; Department of Molecular Genetics and Microbiology, University of New Mexico, 915 Camino de Salud, Albuquerque, NM 87131, United States. Electronic address: amkell@salud.unm.edu.

Publikováno v: Journal of molecular biology [J Mol Biol] 2022 Mar 30; Vol. 434 (6), pp. 167230. Date of Electronic Publication: 2021 Sep 04.

Endomembrane targeting of human OAS1 p46 augments antiviral activity.

Autor: Soveg FW; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Schwerk J; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Gokhale NS; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Cerosaletti K; Benaroya Research Institute at Virginia Mason, Seattle, United States., Smith JR; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Pairo-Castineira E; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom., Kell AM; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States.; Department of Molecular Genetics and Microbiology, School of Medicine, University of New Mexico, Albuquerque, United States., Forero A; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States.; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, United States., Zaver SA; Department of Microbiology, School of Medicine, University of Washington, Seattle, United States., Esser-Nobis K; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Roby JA; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Hsiang TY; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Ozarkar S; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Clingan JM; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., McAnarney ET; Department of Microbiology and Immunology, University of Texas Medical Center, Galveston, United States., Stone AE; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States.; Department of Basic Sciences, College of Osteopathic Medicine, Touro University Nevada, Henderson, United States., Malhotra U; Department of Infectious Disease, Virginia Mason Medical Center, Seattle, United States.; Department of Medicine, Section of Infectious Diseases, University of Washington, Seattle, United States., Speake C; Benaroya Research Institute at Virginia Mason, Seattle, United States., Perez J; Cancer Virology Program, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, United States., Balu C; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Allenspach EJ; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, United States., Hyde JL; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, United States., Menachery VD; Department of Microbiology and Immunology, University of Texas Medical Center, Galveston, United States., Sarkar SN; Cancer Virology Program, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, United States., Woodward JJ; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States.; Department of Microbiology, School of Medicine, University of Washington, Seattle, United States., Stetson DB; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom., Buckner JH; Benaroya Research Institute at Virginia Mason, Seattle, United States., Gale M Jr; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States., Savan R; Department of Immunology, School of Medicine, University of Washington, Seattle, United States.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, United States.

Publikováno v: ELife [Elife] 2021 Aug 03; Vol. 10. Date of Electronic Publication: 2021 Aug 03.

Highly Effective Inactivation of SARS-CoV-2 by Conjugated Polymers and Oligomers.

Autor: Monge FA; Center for Biomedical Engineering, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States.; Biomedical Engineering Graduate Program, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States., Jagadesan P; Department of Chemistry, University of Texas at San Antonio, San Antonio 78249-1644, Texas, United States., Bondu V; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque 87131-0001, New Mexico, United States., Donabedian PL; Center for Biomedical Engineering, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States.; Nanoscience and Microsystems Engineering Graduate Program, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States., Ista L; Center for Biomedical Engineering, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States.; Department of Chemical and Biological Engineering, University of New Mexico, Albuquerque 87131, New Mexico, United States., Chi EY; Center for Biomedical Engineering, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States.; Department of Chemical and Biological Engineering, University of New Mexico, Albuquerque 87131, New Mexico, United States., Schanze KS; Department of Chemistry, University of Texas at San Antonio, San Antonio 78249-1644, Texas, United States., Whitten DG; Center for Biomedical Engineering, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States.; Department of Chemical and Biological Engineering, University of New Mexico, Albuquerque 87131, New Mexico, United States.; Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque 87131-0001, New Mexico, United States., Kell AM; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque 87131-0001, New Mexico, United States.

Publikováno v: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 Dec 16; Vol. 12 (50), pp. 55688-55695. Date of Electronic Publication: 2020 Dec 02.

Highly Effective Inactivation of SARS-CoV-2 by Conjugated Polymers and Oligomers.

Autor: Schanze KS, Whitten DG, Kell AM, Chi EY, Ista LK, Monge FA, Jagadesan P, Bondu V, Donabedian PL

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2020 Oct 06. Date of Electronic Publication: 2020 Oct 06.

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions.

Autor: Schwerk J; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Soveg FW; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Ryan AP; Section of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA., Thomas KR; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Hatfield LD; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Ozarkar S; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Forero A; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Kell AM; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., Roby JA; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA., So L; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA.; Immunology Program, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA., Hyde JL; Department of Microbiology, School of Medicine, University of Washington, Seattle, WA, USA., Gale M Jr; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA, USA., Daugherty MD; Section of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA. mddaugherty@ucsd.edu., Savan R; Department of Immunology, School of Medicine, University of Washington, Seattle, WA, USA. savanram@uw.edu.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA, USA. savanram@uw.edu.

Publikováno v: Nature immunology [Nat Immunol] 2019 Dec; Vol. 20 (12), pp. 1610-1620. Date of Electronic Publication: 2019 Nov 18.