Preclinical Evaluation of ⁸⁹ Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy.

Autor: Maresca KP; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA. kevin.maresca@pfizer.com., Chen J; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Mathur D; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA.; Regneron Pharmaceuticals, Tarrytown, NY, USA., Giddabasappa A; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Root A; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA.; Generate Biomedicines, Inc, Cambridge, MA, USA., Narula J; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., King L; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Schaer D; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Golas J; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA.; Regneron Pharmaceuticals, Tarrytown, NY, USA., Kobylarz K; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Rosfjord E; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA.; Black Diamond Therapeutics, New York, NY, USA., Keliher E; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Chen L; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Ram S; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Pickering EH; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Hardwick JS; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Rejto PA; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA., Hussein A; Invicro, A Konica Minolta Company, New Haven, USA., Ilovich O; Invicro, A Konica Minolta Company, New Haven, USA., Staton K; Evergreen Theragnostics, Jersey City, NJ, USA.; Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wilson I; ImaginAb Inc., Inglewood, CA, USA., McCarthy TJ; Worldwide Research, Development & Medicine, Pfizer Inc, New York, USA.

Publikováno v: Molecular imaging and biology [Mol Imaging Biol] 2021 Dec; Vol. 23 (6), pp. 941-951. Date of Electronic Publication: 2021 Jun 18.

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis.

Autor: Panizzi P; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA., Krohn-Grimberghe M; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.; University Heart Center Freiburg, 79106 Freiburg, Germany., Keliher E; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Ye YX; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Grune J; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Frodermann V; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Sun Y; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Muse CG; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA., Bushey K; Green Mountain Antibodies, Burlington, VT 05401, USA., Iwamoto Y; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., van Leent MMT; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Meerwaldt A; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Toner YC; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Munitz J; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Maier A; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Soultanidis G; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Calcagno C; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Pérez-Medina C; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Centro Nacional de Investigaciones Cardivasculares, 28029 Madrid, Spain., Carlucci G; Bernard and Irene Schwarz Center for Biomedical Imaging, New York University, New York, NY 10016, USA., Riddell KP; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Barney S; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Horne G; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Anderson B; Swine Research and Education Center, Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA., Maddur-Appajaiah A; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Verhamme IM; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Bock PE; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Wojtkiewicz GR; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Courties G; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Swirski FK; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA., Church WR; Green Mountain Antibodies, Burlington, VT 05401, USA., Walz PH; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Tillson DM; Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA., Mulder WJM; Biomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands., Nahrendorf M; Center for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA. mnahrendorf@mgh.harvard.edu.; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Department of Internal Medicine I, University Hospital Würzburg, 97080 Würzburg, Germany.

Publikováno v: Science translational medicine [Sci Transl Med] 2020 Nov 04; Vol. 12 (568).

[ 18 F]-Radiolabelled Nanoplatforms: A Critical Review of Their Intrinsic Characteristics, Radiolabelling Methods, and Purification Techniques.

Autor: Deleuziere, Maëlle^1,2,3 (AUTHOR) maelle.deleuziere@univ-tlse3.fr, Benoist, Éric¹ (AUTHOR) eric.benoist@univ-tlse3.fr, Quelven, Isabelle² (AUTHOR), Gras, Emmanuel⁴ (AUTHOR) emmanuel.gras@univ-tlse3.fr, Amiens, Catherine³ (AUTHOR) catherine.amiens@lcc-toulouse.fr

Publikováno v: Molecules. Apr2024, Vol. 29 Issue 7, p1537. 65p.

Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models.

Autor: Li A; Department of Radiology, Huashan Hospital, Fudan University, 12 Urumchi Road, Shanghai, 200040, China.; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA.; Department of Radiology, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, 250012, China., Wu Y; Department of Radiology, Huashan Hospital, Fudan University, 12 Urumchi Road, Shanghai, 200040, China.; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Linnoila J; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Pulli B; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA.; Department of Radiology, Institute for Innovation in Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA., Wang C; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Zeller M; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Ali M; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Lewandrowski GK; Molecular Neurogenetics Unit, Neuroscience Center, 149 13th St., Charlestown, MA, 02129, USA., Li J; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Tricot B; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Keliher E; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Wojtkiewicz GR; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA., Fulci G; Brain Tumor Research Center, Simches Research Building, Neurosurgery Service, Massachusetts General Hospital, Boston, MA, 02114, USA., Feng X; Department of Radiology, Huashan Hospital, Fudan University, 12 Urumchi Road, Shanghai, 200040, China., Tannous BA; Molecular Neurogenetics Unit, Neuroscience Center, 149 13th St., Charlestown, MA, 02129, USA., Yao Z; Department of Radiology, Huashan Hospital, Fudan University, 12 Urumchi Road, Shanghai, 200040, China. aocnhnr@126.com., Chen JW; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA, 02114, USA. jwchen@mgh.harvard.edu.; Department of Radiology, Institute for Innovation in Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA. jwchen@mgh.harvard.edu.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2016 Dec; Vol. 65 (12), pp. 1545-1554. Date of Electronic Publication: 2016 Oct 08.

Translocator Protein 18 kDa (TSPO): A Promising Molecular Target for Image-Guided Surgery of Solid Cancers.

Autor: Wongso, Hendris^1,2 (AUTHOR) hend042@brin.go.id, Kurniawan, Ahmad¹ (AUTHOR), Setiadi, Yanuar³ (AUTHOR), Kusumaningrum, Crhisterra E.¹ (AUTHOR), Widyasari, Eva M.¹ (AUTHOR), Wibawa, Teguh H.A.¹ (AUTHOR), Mahendra, Isa^1,2 (AUTHOR), Febrian, Muhamad B.¹ (AUTHOR), Sriyani, Maula E.¹ (AUTHOR), Halimah, Iim¹ (AUTHOR), Daruwati, Isti^1,2,4 (AUTHOR), Gunawan, Rudi^1,2,4 (AUTHOR), Achmad, Arifudin^2,5,6 (AUTHOR), Nugraha, Dwianto H.⁷ (AUTHOR), Lesmana, Ronny^8,9,10 (AUTHOR), Nugraha, Ari S.^11,12 (AUTHOR)

Publikováno v: Advanced Pharmaceutical Bulletin. 2024, Vol. 14 Issue 1, p86-104. 19p.