Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Keliang Tang"'
Autor:
Kristen M Skillman, Karthikeyan Diraviyam, Asis Khan, Keliang Tang, David Sept, L David Sibley
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002280 (2011)
Apicomplexan parasites rely on a novel form of actin-based motility called gliding, which depends on parasite actin polymerization, to migrate through their hosts and invade cells. However, parasite actins are divergent both in sequence and function
Externí odkaz:
https://doaj.org/article/9bb1fe46a1f7486eae70f4cba7a02272
Autor:
William J. Zuercher, Scott A. Wildman, James W. Janetka, Emily A. Hull-Ryde, Keliang Tang, Raymond Hui, William P. Janzen, L. David Sibley, Michael A. Stashko, Catherine Simpson, Matthieu Schapira, Dmitri Kireev, Nathaniel G. Jones
Publikováno v:
ACS Infectious Diseases. 2:194-206
The protozoan parasite Toxoplasma gondii secretes a family of serine-threonine protein kinases into its host cell in order to disrupt signaling and alter immune responses. One prominent secretory effector is the rhoptry protein 18 (ROP18), a serine-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6603c5e3250cc54be9862720fbf409c
https://doi.org/10.1021/acsinfecdis.5b00102
https://doi.org/10.1021/acsinfecdis.5b00102
Autor:
Catherine, Simpson, Nathaniel G, Jones, Emily A, Hull-Ryde, Dmitri, Kireev, Michael, Stashko, Keliang, Tang, Jim, Janetka, Scott A, Wildman, William J, Zuercher, Matthieu, Schapira, Raymond, Hui, William, Janzen, L David, Sibley
Publikováno v:
ACS infectious diseases. 2(3)
The protozoan parasite Toxoplasma gondii secretes a family of serine-threonine protein kinases into its host cell in order to disrupt signaling and alter immune responses. One prominent secretory effector is the rhoptry protein 18 (ROP18), a serine-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0abfb3f3dbe12d89cfe11d94dd2fc2b
https://pubmed.ncbi.nlm.nih.gov/27379343
https://pubmed.ncbi.nlm.nih.gov/27379343
Autor:
Kevan M. Shokat, L. David Sibley, Mark S. Kuhlenschmidt, Theresa B. Kuhlenschmidt, Florentine U. Rutaganira, Shaojung Long, Keliang Tang
Publikováno v:
Antimicrobial agents and chemotherapy, vol 60, iss 1
Cryptosporidiosis is a serious diarrheal disease in immunocompromised patients and malnourished children, and treatment is complicated by a lack of adequate drugs. Recent studies suggest that the natural occurrence of a small gatekeeper residue in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0bee0104e60522021f265fa070834e
https://escholarship.org/uc/item/75w4n19n
https://escholarship.org/uc/item/75w4n19n
Publikováno v:
The EMBO Journal. 31:4524-4534
Calcium signalling coordinates motility, cell invasion, and egress by apicomplexan parasites, yet the key mediators that transduce these signals remain largely unknown. One underlying assumption is that invasion into and egress from the host cell dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97d94133eb56a58150debcf490aee660
https://doi.org/10.1038/emboj.2012.299
https://doi.org/10.1038/emboj.2012.299
Autor:
Keliang Tang, Jitender P. Dubey, Michael S. Behnke, Asis Khan, L. David Sibley, John C. Wootton
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9631-9636
The population structure of Toxoplasma gondii includes three highly prevalent clonal lineages referred to as types I, II, and III, which differ greatly in virulence in the mouse model. Previous studies have implicated a family of serine/threonine pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfd6a4602b1bd074f55802b471ef6a9
https://doi.org/10.1073/pnas.1015338108
https://doi.org/10.1073/pnas.1015338108
A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii
Autor:
Chunlei Su, Antonio Barragan, Maria E. Jerome, L.D. Sibley, Michael S. Behnke, Sarah J. Fentress, Michael W. White, Sonya Taylor, Wandy L. Beatty, Keliang Tang, John C. Wootton, H. El Hajj, Blima Fux
Publikováno v:
Science. 314:1776-1780
Toxoplasma gondii strains differ dramatically in virulence despite being genetically very similar. Genetic mapping revealed two closely adjacent quantitative trait loci on parasite chromosome VIIa that control the extreme virulence of the type I line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e82a3983e5ae5cff10d56fc78ff0836
https://doi.org/10.1126/science.1133643
https://doi.org/10.1126/science.1133643
Publikováno v:
International Journal for Parasitology. 34:1265-1271
Gregarines are protozoan parasites of invertebrates in the phylum Apicomplexa. We employed an expressed sequence tag strategy in order to dissect the molecular processes of sexual or gametocyst development of gregarines. Expressed sequence tags provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bdf77c72e6c9f5626e84d036f2f1d6
https://doi.org/10.1016/j.ijpara.2004.08.004
https://doi.org/10.1016/j.ijpara.2004.08.004
Autor:
Minh Ho, Joseph M. Palys, William G. Hanson, Matthew J. Heckert, Tina Jenq, Diane Burgess, Edward J. Ralston, Keliang Tang, Neal Gutterson
Publikováno v:
The Plant Journal. 31:113-125
Ablation of cells by the controlled expression of a lethal gene can be used to engineer plant traits such as male sterility and disease resistance. However, it may not be possible to achieve sufficient specificity of expression to prevent secondary e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d66ad91256dcd2a6dc32c02bce81451
https://doi.org/10.1046/j.1365-313x.2002.01330.x
https://doi.org/10.1046/j.1365-313x.2002.01330.x
Autor:
Jitender P. Dubey, Karen W. Sverlow, Patricia A. Conrad, Keliang Tang, L. David Sibley, Daniel K. Howe
Publikováno v:
Clinical and Vaccine Immunology. 9:611-615
Neosporosis is an economically important disease of dairy cattle caused by the protozoanNeospora caninum. Diagnostic tests for neosporosis are complicated by the potential for cross-reaction of antibodies to antigens that are similar betweenN. caninu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6b20274e2caebaec93043c03be1f27
https://doi.org/10.1128/cdli.9.3.611-615.2002
https://doi.org/10.1128/cdli.9.3.611-615.2002