Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Kelen Cristina Ribeiro"'
Autor:
Renata Nacasaki Silvestre, Jiri Eitler, Julia Teixeira Cottas de Azevedo, Mariane Cariati Tirapelle, Daianne Maciely Carvalho Fantacini, Lucas Eduardo Botelho de Souza, Kamilla Swiech, Dimas Tadeu Covas, Rodrigo T. Calado, Paola Ortiz Montero, Kelen Cristina Ribeiro Malmegrim, Marxa L. Figueiredo, Torsten Tonn, Virginia Picanço-Castro
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural killer 92 (NK-92) cells are an attractive therapeutic approach as alternative chimeric antigen receptor (CAR) carriers, different from T cells, once they can be used in the allogeneic setting. The modest in vivo outcomes observed
Externí odkaz:
https://doaj.org/article/3c70f6d73d3641458e2db201ea935271
Autor:
Virgínia Picanco-Castro, Cristiano Gonçalves Pereira, Kamilla Swiech, Kelen Cristina Ribeiro Malmegrim, Dimas Tadeu Covas, Geciane Silveira Porto
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 6, Pp 1424-1433 (2020)
The purpose of this study is to mine CAR-T patents and therapies under development, to design a landscape of the sector and to understand key therapy segments and their current trends. The study analyzed the entire market, consisting of 1624 patent f
Externí odkaz:
https://doaj.org/article/ad24c6be49d24c66899e69c699961480
Autor:
Virgínia Picanço-Castro, Pablo Diego Moço, Amanda Mizukami, Leticia Delfini Vaz, Marcelo de Souza Fernandes Pereira, Renata Nacasaki Silvestre, Júlia Teixeira Cottas de Azevedo, Aline de Sousa Bomfim, Mario Soares de Abreu Neto, Kelen Cristina Ribeiro Malmegrim, Kamilla Swiech, Dimas Tadeu Covas
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 42, Iss 2, Pp 150-158 (2020)
Introduction: Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes
Externí odkaz:
https://doaj.org/article/46b2df83e5f24db88e2dd8999c65cfb5
Autor:
Luciana Ribeiro Jarduli‐Maciel, Júlia Teixeira Cottas de Azevedo, Emmanuel Clave, Thalita Cristina de Mello Costa, Lucas Coelho Marlière Arruda, Isabelle Fournier, Patrícia Vianna Bonini Palma, Keli Cristina Lima, Juliana Bernardes Elias, Ana Beatriz PL Stracieri, Fabiano Pieroni, Renato Cunha, Luiz Guilherme Darrigo‐Júnior, Carlos Eduardo Settani Grecco, Dimas Tadeu Covas, Ana Cristina Silva‐Pinto, Gil Cunha De Santis, Belinda Pinto Simões, Maria Carolina Oliveira, Antoine Toubert, Kelen Cristina Ribeiro Malmegrim
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 4, Pp n/a-n/a (2022)
Abstract Objectives Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only currently available curative treatment for sickle cell disease (SCD). Here, we comprehensively evaluated the reconstitution of T‐ and B‐cell compart
Externí odkaz:
https://doaj.org/article/c781cf229ea44de68805e00caa2a983d
Autor:
Júlia Teixeira Cottas de Azevedo, Thalita Cristina de Mello Costa, Keli Cristina Lima, Thiago Trovati Maciel, Patrícia Vianna Bonini Palma, Luiz Guilherme Darrigo-Júnior, Carlos Eduardo Setanni Grecco, Ana Beatriz P. L. Stracieri, Juliana Bernardes Elias, Fabiano Pieroni, Renato Luiz Guerino-Cunha, Ana Cristina Silva Pinto, Gil Cunha De Santis, Dimas Tadeu Covas, Olivier Hermine, Belinda Pinto Simões, Maria Carolina Oliveira, Kelen Cristina Ribeiro Malmegrim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only currently available curative treatment for sickle cell disease (SCD). However, the effects of HSCT on SCD pathophysiology are poorly elucidated. Here, we assessed red blood ce
Externí odkaz:
https://doaj.org/article/0f750815091a46f1913f64b81244f2f3
Autor:
Juçara Gastaldi Cominal, Maira da Costa Cacemiro, Maria Gabriela Berzoti-Coelho, Illy Enne Gomes Pereira, Fabiani Gai Frantz, Elizabeth Xisto Souto, Dimas Tadeu Covas, Lorena Lobo de Figueiredo-Pontes, Maria Carolina Oliveira, Kelen Cristina Ribeiro Malmegrim, Fabíola Attié de Castro
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundEssential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) are clonal hematological diseases classified as Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). MPN pathogenesis is associated with
Externí odkaz:
https://doaj.org/article/35f559b49651421b800ed268af1b7b4a
Autor:
Karina Tozatto-Maio, Robert Girot, Indou Deme Ly, Ana Cristina Silva Pinto, Vanderson Rocha, Francisco Fernandes, Ibrahima Diagne, Yahia Benzerara, Carla L. Dinardo, Julia Pavan Soler, Simone Kashima, Itauá Leston Araujo, Chantal Kenzey, Guilherme H. H. Fonseca, Evandra S. Rodrigues, Fernanda Volt, Luciana Jarduli, Annalisa Ruggeri, Christina Mariaselvam, Sandra F. M. Gualandro, Hanadi Rafii, Barbara Cappelli, Felipe Melo Nogueira, Graziana Maria Scigliuolo, Renato Luiz Guerino-Cunha, Kelen Cristina Ribeiro Malmegrim, Belinda P. Simões, Eliane Gluckman, Ryad Tamouza
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sickle cell disease (SCD), the most common monogenic disease worldwide, is marked by a phenotypic variability that is, to date, only partially understood. Because inflammation plays a major role in SCD pathophysiology, we hypothesized that single nuc
Externí odkaz:
https://doaj.org/article/67cb8a7ed9504d0aaebc582eaf5a2b7d
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/9d73568cd7a848daac5ee844d2aa1c19
Autor:
Jaquellyne Gurgel Penaforte-Saboia, Carlos Eduardo Barra Couri, Virginia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Lívia Aline De Araújo Batista, Lenita Zajdenverg, Carlos Antonio Negrato, Kelen Cristina Ribeiro Malmegrim, Daniela Aparecida Moraes, Juliana Bernardes Elias Dias, Maria Carolina Oliveira, Akhtar Hussain, Marilia Brito Gomes, Renan Magalhães Montenegro
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Objective: To evaluate the association between insulin-dose adjusted A1C (IDAA1c) and microvascular complications (MC) and hypoglycemia in a representative Brazilian population of Type 1 diabetes mellitus (T1DM) patients.Research Design and Methods:
Externí odkaz:
https://doaj.org/article/511d1f75aa2f4ebd9196c872ec6acc8d
Autor:
Juçara Gastaldi Cominal, Maira da Costa Cacemiro, Belinda Pinto-Simões, Hans-Jochem Kolb, Kelen Cristina Ribeiro Malmegrim, Fabíola Attié de Castro
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Homoeostasis of bone marrow microenvironment depends on a precise balance between cell proliferation and death, which is supported by the cellular-extracellular matrix crosstalk. Multipotent mesenchymal stromal cells (MSC) are the key elements to pro
Externí odkaz:
https://doaj.org/article/cee2a7c291374ec0a4e1d7a00e25db04