Dynamics of cell-free tumor DNA correlate with early MRI response during chemoradiotherapy in rectal cancer.

Autor: Clasen K; Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany. kerstin.clasen@med.uni-tuebingen.de., Gani C; Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany., Schuetz L; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany., Clasen S; Department of Diagnostic and Interventional Radiology, District Hospital Reutlingen, Reutlingen, Germany., Ballin N; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany., Bonzheim I; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Orth M; Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany., Ossowski S; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany., Riess O; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany., Niyazi M; Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany., Schroeder C; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany., Kelemen O; Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Tübingen, Germany.

Publikováno v: Radiation oncology (London, England) [Radiat Oncol] 2024 Nov 06; Vol. 19 (1), pp. 153. Date of Electronic Publication: 2024 Nov 06.

Algorithm-Based Modular Psychotherapy Alleviates Brain Inflammation in Generalized Anxiety Disorder.

Autor: Kéri S; Sztárai Institute, University of Tokaj, 3944 Sárospatak, Hungary.; Department of Physiology, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary., Kancsev A; Department of Psychiatry and Psychotherapy, András Jósa Hospital, 4400 Nyíregyháza, Hungary., Kelemen O; Department of Behavioral Sciences, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.; Department of Psychiatry and Psychotherapy, Bács-Kiskun County Hospital, 6000 Kecskemét, Hungary.

Publikováno v: Life (Basel, Switzerland) [Life (Basel)] 2024 Jul 18; Vol. 14 (7). Date of Electronic Publication: 2024 Jul 18.

Diagnostic genome sequencing improves diagnostic yield: a prospective single-centre study in 1000 patients with inherited eye diseases.

Autor: Weisschuh N; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Mazzola P; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Zuleger T; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Schaeferhoff K; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Kühlewein L; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Kortüm F; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Witt D; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Liebmann A; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Falb R; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Pohl L; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Reith M; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Stühn LG; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Bertrand M; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Müller A; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Kelemen O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Kelbsch C; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Kernstock C; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Richter P; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Sadler F; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Demidov G; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Schütz L; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Admard J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Sturm M; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Grasshoff U; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Tonagel F; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Heinrich T; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; MVZ für Humangenetik und Molekularpathologie, Rostock, Germany., Nasser F; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Wissinger B; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics (IBMI), University of Tübingen, Tübingen, Germany., Kohl S; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Riess O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Rare Disease, University of Tübingen, Tübingen, Germany., Stingl K; University Eye Hospital, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany tobias.haack@med.uni-tuebingen.de Katarina.Stingl@med.uni-tuebingen.de., Haack TB; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany tobias.haack@med.uni-tuebingen.de Katarina.Stingl@med.uni-tuebingen.de.; Center for Rare Disease, University of Tübingen, Tübingen, Germany.

Publikováno v: Journal of medical genetics [J Med Genet] 2024 Jan 19; Vol. 61 (2), pp. 186-195. Date of Electronic Publication: 2024 Jan 19.

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Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients.

Autor: Menzel M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics (IBMI), University of Tübingen, Tübingen, Germany., Kral S; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Personalized Medicine (ZPM), Freiburg, Germany., Metzger P; Center for Personalized Medicine (ZPM), Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Horak P; Center for Personalized Medicine (ZPM), Heidelberg, Germany.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Marienfeld R; Institute of Pathology, University Hospital Ulm, Ulm, Germany.; Center for Personalized Medicine (ZPM), Ulm, Germany., Boerries M; Center for Personalized Medicine (ZPM), Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Comprehensive Cancer Center Freiburg (CCCF), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Wolter S; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Personalized Medicine (ZPM), Freiburg, Germany., Ball M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Neumann O; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Armeanu-Ebinger S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Schroeder C; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Matysiak U; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Personalized Medicine (ZPM), Freiburg, Germany., Goldschmid H; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Schipperges V; Center for Personalized Medicine (ZPM), Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Fürstberger A; Institute of Pathology, University Hospital Ulm, Ulm, Germany.; Center for Personalized Medicine (ZPM), Ulm, Germany.; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Allgäuer M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Eberhardt T; Institute of Pathology, University Hospital Ulm, Ulm, Germany.; Center for Personalized Medicine (ZPM), Ulm, Germany., Niewöhner J; Institute of Pathology, University Hospital Ulm, Ulm, Germany., Blaumeiser A; Center for Personalized Medicine (ZPM), Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Ploeger C; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Haack TB; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Tay TKY; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany.; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Kelemen O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Pauli T; Center for Personalized Medicine (ZPM), Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kirchner M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Kluck K; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Ott A; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Renner M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Admard J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Gschwind A; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Center for Personalized Medicine (ZPM), Tübingen, Germany., Lassmann S; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Personalized Medicine (ZPM), Freiburg, Germany., Kestler H; Institute of Pathology, University Hospital Ulm, Ulm, Germany.; Center for Personalized Medicine (ZPM), Ulm, Germany., Fend F; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Illert AL; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79085, Freiburg, Germany.; Medical Department for Hematology and Oncology, Klinikum Rechts der Isar, Technische Universität München, 80333, Munich, Germany.; German Cancer Consortium (DKTK) Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Werner M; Institute for Surgical Pathology, Medical Center, University of Freiburg, Freiburg, Germany.; Center for Personalized Medicine (ZPM), Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Möller P; Institute of Pathology, University Hospital Ulm, Ulm, Germany., Seufferlein TTW; Center for Personalized Medicine (ZPM), Ulm, Germany.; Department of Internal Medicine I, University of Ulm, Ulm, Germany., Malek N; Center for Personalized Medicine (ZPM), Tübingen, Germany.; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany., Schirmacher P; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Fröhling S; Center for Personalized Medicine (ZPM), Heidelberg, Germany.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Kazdal D; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Center for Personalized Medicine (ZPM), Heidelberg, Germany., Budczies J; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. jan.budczies@med.uni-heidelberg.de.; Center for Personalized Medicine (ZPM), Heidelberg, Germany. jan.budczies@med.uni-heidelberg.de.; German Cancer Consortium (DKTK), Heidelberg, Germany. jan.budczies@med.uni-heidelberg.de., Stenzinger A; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. albrecht.stenzinger@med.uni-heidelberg.de.; Center for Personalized Medicine (ZPM), Heidelberg, Germany. albrecht.stenzinger@med.uni-heidelberg.de.; German Cancer Consortium (DKTK), Heidelberg, Germany. albrecht.stenzinger@med.uni-heidelberg.de.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2023 Oct 20; Vol. 7 (1), pp. 106. Date of Electronic Publication: 2023 Oct 20.