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Akademický článek

Effects of inhalation of polyhexamethylene guanidine disinfectant aerosol on immune organs and immune cells in mice

Autor: Zhengli YANG, Naimin SHAO, Yu DING, Jing XU, Junli LIU, Xi LIU, Kelei QIAN, Xinyu HONG

Publikováno v: 环境与职业医学, Vol 41, Iss 8, Pp 855-860 (2024)

BackgroundThe respiratory toxicity of inhaled polyhexamethylene guanidine (PHMG) has been extensively studied since the humidifier disinfectant incident. However, the impacts of inhalation of PHMG on the immune system are not comprehensively studied

Externí odkaz: https://doaj.org/article/8e1987accee9440e866eb4326dcd8ebc

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Akademický článek

Estimation of genotoxicity threshold induced by acute exposure to neodymium nitrate in mice using benchmark dose

Autor: Junli LIU, Yu DING, Xueqing CHENG, Zhengli YANG, Kelei QIAN, Jing XU, Yiyun FAN, Dongsheng YU, Zhiqing ZHENG, Jun YANG, Ning WANG, Xinyu HONG

Publikováno v: 环境与职业医学, Vol 41, Iss 4, Pp 425-430 (2024)

Background The benchmark dose (BMD) method calculates the dose associated with a specific change in response based on a specific dose-response relationship. Compared with the traditional no observed adverse effect level (NOAEL) method, the BMD method

Externí odkaz: https://doaj.org/article/c813f965c4ed4258968a5ec0b3321eb0

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Omarigliptin ameliorated high glucose-induced nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome activation through activating adenosine monophosphate-activated protein kinase α (AMPKα) in renal glomerular endothelial cells

Autor: Yuli Sun, Ling Li, Yun Zhou, Xinyu Hong, Ying Xue, Kelei Qian, Yong Zhao

Publikováno v: Bioengineered, Vol 12, Iss 1, Pp 4805-4815 (2021)
Bioengineered
article-version (VoR) Version of Record

Diabetic nephropathy (DN) is a complication of diabetes that induces the development of end-stage renal disease (ESRD). The pathogenesis of DN is reported to be closely related to the activation of the NOD-like receptor 3 (NLRP3) inflammasome in rena

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aca3db02c2e95739c9b51edff24093f
https://doaj.org/article/e1c611289b7046fe90220f62cddee4b9

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Exposure to zinc oxide nanoparticles affects testicular structure, reproductive development and spermatogenesis in parental and offspring male rats

Autor: Xinyu Hong, Naimin Shao, Lei Yin, Chen Li, Gonghua Tao, Yuli Sun, Kelei Qian, Jun Yang, Ping Xiao, Xiaozhong Yu, Zhijun Zhou

Publikováno v: Annals of translational medicine. 10(13)

This study aimed to comprehensively evaluate the toxicity exerted by zinc oxide nanoparticles (ZnO NPs) on rat testis and its effects on fertility and progeny development.Different concentrations of ZnO NPs were administered by gavage to Sprague Dawl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74476a7c63eec24bb259cd3c7a35ecfb
https://pubmed.ncbi.nlm.nih.gov/35957732

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