Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kelcee A, Everette"'
Autor:
Chang Li, Aphrodite Georgakopoulou, Gregory A. Newby, Kelcee A. Everette, Evangelos Nizamis, Kiriaki Paschoudi, Efthymia Vlachaki, Sucheol Gil, Anna K. Anderson, Theodore Koob, Lishan Huang, Hongjie Wang, Hans-Peter Kiem, David R. Liu, Evangelia Yannaki, André Lieber
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
Individuals with β-thalassemia or sickle cell disease and hereditary persistence of fetal hemoglobin (HPFH) possessing 30% fetal hemoglobin (HbF) appear to be symptom free. Here, we used a nonintegrating HDAd5/35++ vector expressing a highly efficie
Externí odkaz:
https://doaj.org/article/ad903bbc1db4441484b871ef2cf704a3
Autor:
Chang Li, Aphrodite Georgakopoulou, Gregory A Newby, Peter J Chen, Kelcee A Everette, Kiriaki Paschoudi, Efthimia Vlachaki, Sucheol Gil, Anna K Anderson, Theodore Koob, Lishan Huang, Hongjie Wang, Hans-Peter Kiem, David R Liu, Evangelia Yannaki, André Lieber
Publikováno v:
Blood.
Sickle Cell Disease (SCD) is a monogenic disease caused by a nucleotide mutation in the β-globin gene. Current gene therapy studies are mainly focused on lentivirus vector-mediated gene addition or CRISPR/Cas9-mediated fetal globin reactivation, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30af570cb24ad7ab980dfcad37b6d63b
https://doi.org/10.1182/blood.2022018252
https://doi.org/10.1182/blood.2022018252
Autor:
Alvin Hsu, Andrew V. Anzalone, Peyton B. Randolph, James W. Nelson, Simon P. Shen, Kelcee A. Everette, Meirui An, Gregory A. Newby, David R. Liu, Peter J. Chen, Jonathan C. Chen
Publikováno v:
Nature Biotechnology. 40:402-410
Prime editing enables the installation of virtually any combination of point mutations, small insertions or small deletions in the DNA of living cells. A prime editing guide RNA (pegRNA) directs the prime editor protein to the targeted locus and also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10210353dfc4e217eed08131ecc552b
https://doi.org/10.1038/s41587-021-01039-7
https://doi.org/10.1038/s41587-021-01039-7
Autor:
Grace E. McAuley, Gloria Yiu, Patrick C Chang, Gregory A. Newby, Beatriz Campo-Fernandez, Sorel T. Fitz-Gibbon, Xiaomeng Wu, Sung-Hae L. Kang, Amber Garibay, Jeffrey Butler, Valentina Christian, Ryan L. Wong, Kelcee A. Everette, Anthony Azzun, Hila Gelfer, Christopher S. Seet, Aru Narendran, Luis Murguia-Favela, Zulema Romero, Nicola Wright, David R. Liu, Gay M. Crooks, Donald B. Kohn
Publikováno v:
Cell. 186:1398-1416.e23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58db2306d3aa251af0eb4d868d24dc98
https://doi.org/10.1016/j.cell.2023.02.027
https://doi.org/10.1016/j.cell.2023.02.027
Autor:
James W, Nelson, Peyton B, Randolph, Simon P, Shen, Kelcee A, Everette, Peter J, Chen, Andrew V, Anzalone, Meirui, An, Gregory A, Newby, Jonathan C, Chen, Alvin, Hsu, David R, Liu
Publikováno v:
Nature biotechnology. 40(3)
Prime editing enables the installation of virtually any combination of point mutations, small insertions or small deletions in the DNA of living cells. A prime editing guide RNA (pegRNA) directs the prime editor protein to the targeted locus and also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c0c6d00438956b73ad8d027f9f5b9c1
https://pubmed.ncbi.nlm.nih.gov/34880468
https://pubmed.ncbi.nlm.nih.gov/34880468
Autor:
James W. Nelson, Peyton B. Randolph, Simon P. Shen, Kelcee A. Everette, Peter J. Chen, Andrew V. Anzalone, Meirui An, Gregory A. Newby, Jonathan C. Chen, Alvin Hsu, David R. Liu
Publikováno v:
Nature Biotechnology. 40:432-432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b98fa177f9b6e5ce1e0ebc255924dbe
https://doi.org/10.1038/s41587-021-01175-0
https://doi.org/10.1038/s41587-021-01175-0
Autor:
Jingjing Zhang, Shaina N. Porter, Jonathan Yen, Kalin Mayberry, Kaitly J. Woodard, Gregory A. Newby, Jonathan S Yen, Kelcee A. Everette, Mitchell J. Weiss, Anton P. McCaffrey, Thiyagaraj Mayuranathan, Jordana M. Henderson, John F. Tisdale, Shengdar Q. Tsai, Yu Yao, David R. Liu
Publikováno v:
Blood. 136:13-14
Sickle cell disease (SCD) is a chronic, life-altering multisystem disorder that affects millions of individuals worldwide. Strategies for genetic therapy of autologous SCD hematopoietic stem cells (HSCs) include lentiviral vector (LV) delivery of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98778789a1a9e7f259ee4be9341568fb
https://doi.org/10.1182/blood-2020-139016
https://doi.org/10.1182/blood-2020-139016