Diabetic endotheliopathy: RNA-binding proteins as new therapeutic targets

Autor: Cornelius, Victoria A., Yacoub, Andrew, Kelaini, Sophia, Margariti, Andriana ^*

Publikováno v: In International Journal of Biochemistry and Cell Biology February 2021 131

Creating an antibacterial surface on beta TNZT alloys for hip implant applications by laser nitriding

Autor: Lubov Donaghy, Clare, McFadden, Ryan, Kelaini, Sophia, Carson, Louise, Margariti, Andriana, Chan, Chi-Wai

Publikováno v: In Optics and Laser Technology January 2020 121

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy

Autor: Caines, Rachel, Cochrane, Amy, Kelaini, Sophia, Gonzalez, Marta Vila, Yang, Chunbo, Eleftheriadou, Magdalini, Moez, Arya, Stitt, Alan W, Zeng, Lingfang, Grieve, David J, Margariti, Andriana

Publikováno v: Caines, R, Cochrane, A, Kelaini, S, Gonzalez, M V, Yang, C, Eleftheriadou, M, Moez, A, Stitt, A W, Zeng, L, Grieve, D J & Margariti, A 2019, ' The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy ', Journal of Cell Science . https://doi.org/10.1242/jcs.230276

Rationale: Endothelial Cell (ECs) and Vascular Smooth Muscle Cell (VSMCs) dysfunction is central to Cardiovascular Disease pathology. Stem cell therapy holds great promise, but greater understanding of mechanisms underpinning vascular cell differenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::8aec333b4bb8b5e896c40bf8e8904fe9
https://pure.qub.ac.uk/en/publications/the-rnabinding-protein-qki-controls-alternative-splicing-in-vascular-cells-producing-an-effective-model-for-therapy(9654419d-7f59-475f-af22-2db3d63a16aa).html

Enhanced Function of Induced Pluripotent Stem Cell‐Derived Endothelial Cells through ESM1 Signalling

Autor: Vilà-González, Marta, Kelaini, Sophia, Drehmer, Daiana, Caines, Rachel, Tsifaki, Marianna, Margariti, Andriana

Publikováno v: Vilà-González, M, Kelaini, S, Drehmer, D, Caines, R, Tsifaki, M & Margariti, A 2018, ' Enhanced Function of Induced Pluripotent Stem Cell-Derived Endothelial Cells through ESM1 Signalling ', Stem Cells . https://doi.org/10.1002/stem.2936

The mortality rate for (cardio)‐vascular disease is one of the highest in the world, so a healthy functional endothelium is of outmost importance against vascular disease. In this study, human induced pluripotent stem (iPS) cells were reprogrammed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::c3ab8d4920080519d67eec54890d3e5f
https://doi.org/10.1002/stem.2936