Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Keke Ren"'
Autor:
Hozeifa Mohamed Hassan, Xi Liang, Jiaojiao Xin, Yingyan Lu, Qun Cai, Dongyan Shi, Keke Ren, Jun Li, Qi Chen, Jiang Li, Peng Li, Beibei Guo, Hui Yang, Jinjin Luo, Heng Yao, Xingping Zhou, Wen Hu, Jing Jiang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background The key role of thrombospondin 1 (THBS1) in the pathogenesis of acute-on-chronic liver failure (ACLF) is unclear. Here, we present a transcriptome approach to evaluate THBS1 as a potential biomarker in ACLF disease pathogenesis. M
Externí odkaz:
https://doaj.org/article/0ff396ac72ca4cccbfd97b76af1b8bc4
Autor:
Junye Ge, Pengfei Ren, Biqing Tian, Jiaqi Li, Chuchu Qi, Qiyi Huang, Keke Ren, Erling Hu, Honghui Mao, Ying Zang, Shengxi Wu, Qian Xue, Wenting Wang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110165- (2024)
Summary: Self-grooming is an innate stereotyped behavior influenced by sense and emotion. It is considered an important characteristic in various disease models. However, the neural circuit mechanism underlying sensory-induced and emotion-driven self
Externí odkaz:
https://doaj.org/article/ee2dd881bb634082b33355cbaa0ff65d
Autor:
Jiaxian Chen, Shiwen Ma, Hui Yang, Xi Liang, Heng Yao, Beibei Guo, Deying Chen, Jing Jiang, Dongyan Shi, Jiaojiao Xin, Keke Ren, Xingping Zhou, Yun Li, Lei Geng, Jun Li
Publikováno v:
Bioactive Materials, Vol 26, Iss , Pp 452-464 (2023)
Developing functional ductal organoids (FDOs) is essential for liver regenerative medicine. We aimed to construct FDOs with biliary tree networks in rat decellularized liver scaffolds (DLSs) with primary cholangiocytes isolated from mouse bile ducts.
Externí odkaz:
https://doaj.org/article/869acd17462641f5b2041d3566572757
Autor:
Xi Liang, Peng Li, Jing Jiang, Jiaojiao Xin, Jinjin Luo, Jiaqi Li, Pengcheng Chen, Keke Ren, Qian Zhou, Beibei Guo, Xingping Zhou, Jiaxian Chen, Lulu He, Hui Yang, Wen Hu, Shiwen Ma, Bingqi Li, Xin Chen, Dongyan Shi, Jun Li
Publikováno v:
JHEP Reports, Vol 5, Iss 9, Pp 100848- (2023)
Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a complex syndrome associated with high short-term mortality. This study aims to reveal the molecular basis and identify novel HBV-ACLF biomarkers. Methods: Seventy patients
Externí odkaz:
https://doaj.org/article/36883cfd57a749cdbd72a33d0ec8f6aa
Autor:
Peng Li, Xi Liang, Jinjin Luo, Jiaqi Li, Jiaojiao Xin, Jing Jiang, Dongyan Shi, Yingyan Lu, Hozeifa Mohamed Hassan, Qian Zhou, Shaorui Hao, Huafen Zhang, Tianzhou Wu, Tan Li, Heng Yao, Keke Ren, Beibei Guo, Xingping Zhou, Jiaxian Chen, Lulu He, Hui Yang, Wen Hu, Shiwen Ma, Bingqi Li, Shaoli You, Shaojie Xin, Yu Chen, Jun Li
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 32, Iss , Pp 100638- (2023)
Summary: Background: Liver transplantation (LT) is an effective therapy for acute-on-chronic liver failure (ACLF) but is limited by organ shortages. We aimed to identify an appropriate score for predicting the survival benefit of LT in HBV-related AC
Externí odkaz:
https://doaj.org/article/1607db3f94b9431da9f98fcefd1acf22
Autor:
Ming Zhang, Jian Wang, Kaixiang Zhang, Guozhen Lu, Yuming Liu, Keke Ren, Wenting Wang, Dazhuan Xin, Lingli Xu, Honghui Mao, Junlin Xing, Xingchun Gao, Weilin Jin, Kalen Berry, Katsuhiko Mikoshiba, Shengxi Wu, Q. Richard Lu, Xianghui Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Myelin formation is regulated by epigenetic mechanisms and ensures proper neuronal function during development and after demyelination. Here, the authors show that TET1, a DNA hydroxymethylase, regulates myelination during development and remyelinati
Externí odkaz:
https://doaj.org/article/e1cbd11d253c49be9a1549ae252b0873
Autor:
Chuchu Qi, Andi Chen, Honghui Mao, Erling Hu, Junye Ge, Guaiguai Ma, Keke Ren, Qian Xue, Wenting Wang, Shengxi Wu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Environmental factors, such as medication during pregnancy, are one of the major causes of autism spectrum disorder (ASD). Valproic acid (VPA) intake during pregnancy has been reported to dramatically elevate autism risk in offspring. Recently, resea
Externí odkaz:
https://doaj.org/article/fd0ebc128a8a498fa236606b58a8f4b4
Autor:
Xianghui Zhao, Ming Zhang, Yuming Liu, Haiying Liu, Keke Ren, Qian Xue, Haifeng Zhang, Na Zhi, Wenting Wang, Shengxi Wu
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103485- (2021)
Summary: Terahertz (THz) frequency occupies a large portion of the electromagnetic spectrum that is between the infrared and microwave regions. Recent advances in THz application have stimulated interests regarding the biological effects within this
Externí odkaz:
https://doaj.org/article/15440128a60e48ad928e7b5da6256bd7
Autor:
Haiying Liu, Xin Huang, Jinwei Xu, Honghui Mao, Yaohao Li, Keke Ren, Guaiguai Ma, Qian Xue, Huiren Tao, Shengxi Wu, Wenting Wang
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100417- (2021)
Self-grooming is an innate, cephalo-caudal progression of body cleaning behaviors that are found in normal rodents but exhibit repetitive and stereotyped patterns in several mouse models, such as autism spectrum disorders (ASDs). It is also recognize
Externí odkaz:
https://doaj.org/article/afbcc5e69918403ea7dcae54442cf8c3
Autor:
Suwan Sun, Lunzhi Yuan, Zhanglu An, Dongyan Shi, Jiaojiao Xin, Jing Jiang, Keke Ren, Jiaxian Chen, Beibei Guo, Xingping Zhou, Qian Zhou, Xiaojun Jin, Sihan Ruan, Tong Cheng, Ningshao Xia, Jun Li
Publikováno v:
Stem Cell Research, Vol 47, Iss , Pp 101900- (2020)
Background & aims: Biliary injury is one of the main pathological mechanisms of fulminant hepatic failure (FHF). Delta-like ligand 4 (DLL4)-mediated Notch activation contributes to reversing biliary injury; however, the specific role of DLL4 in bilia
Externí odkaz:
https://doaj.org/article/b96ca7ee47d64bddb0592e188184937d