Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kejia Kan"'
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 25, Iss 5, p 151 (2024)
Background: The coronary no-reflow (NR) phenomenon is an independent predictor of major adverse cardiac events (MACEs). This study aimed to establish a clinical and comprehensive nomogram for predicting NR in acute myocardial infarction (AMI) patient
Externí odkaz:
https://doaj.org/article/670c304bafbc4a57abdd3978839c71b2
Autor:
Jian Zhang, Vytaute Starkuviene, Holger Erfle, Zhaohui Wang, Manuel Gunkel, Ziwei Zeng, Carsten Sticht, Kejia Kan, Nuh Rahbari, Michael Keese
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In response to vascular injury vascular smooth muscle cells (VSMCs) alternate between a differentiated (contractile) and a dedifferentiated (synthetic) state or phenotype. Although parts of the signaling cascade regulating the phenotypic swi
Externí odkaz:
https://doaj.org/article/a7ab47dfccb9422cbc7f1f64a29359f7
Autor:
Feng Guo, Kejia Kan, Felix Rückert, Wolfgang Rückert, Lin Li, Johannes Eberhard, Tobias May, Carsten Sticht, Wilhelm G. Dirks, Christoph Reißfelder, Prama Pallavi, Michael Keese
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13530 (2023)
There is an ongoing need for patient-specific chemotherapy for pancreatic cancer. Tumour cells isolated from human tissues can be used to predict patients’ response to chemotherapy. However, the isolation and maintenance of pancreatic cancer cells
Externí odkaz:
https://doaj.org/article/958386464ae94330950a5f1ba0470c83
Autor:
Haozhe Qi, Kejia Kan, Carsten Sticht, Katrin Bennewitz, Shu Li, Xin Qian, Gernot Poschet, Jens Kroll
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
IntroductionDiabetes mellitus (DM) is associated with physiological disorders such as delayed wound healing, diabetic retinopathy, diabetic nephropathy, and diabetic peripheral neuropathy (DPN). Over 50% of diabetic patients will develop DPN, charact
Externí odkaz:
https://doaj.org/article/96ce8bb5d0794433b7d077a97ffed98b
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1052 (2022)
Background: There is still an unmet need for therapeutic drugs for patients with an abdominal aortic aneurysm (AAA), especially for candidates unsuitable for surgical or interventional repair. Therefore, the purpose of this in silico study is to iden
Externí odkaz:
https://doaj.org/article/87be9470296a467db4c7e11aa9f80eb7
Autor:
Zhaohui Wang, Ziwei Zeng, Vytaute Starkuviene, Holger Erfle, Kejia Kan, Jian Zhang, Manuel Gunkel, Carsten Sticht, Nuh Rahbari, Michael Keese
Publikováno v:
Genes, Vol 13, Iss 4, p 640 (2022)
To identify miRNAs that are involved in cell migration in human umbilical vein endothelial cells (HUVECs), we employed RNA sequencing under high glucose incubation and text mining within the databases miRWalk and TargetScanHuman using 83 genes that r
Externí odkaz:
https://doaj.org/article/68b9edca0fa64c9aac806335699cca0c
Autor:
Kejia Kan, Yifei Mu, Marielle Bouschbacher, Carsten Sticht, Natalia Kuch, Martin Sigl, Nuh Rahbari, Norbert Gretz, Prama Pallavi, Michael Keese
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 829 (2021)
Blue light regulates biological function in various cells, such as proliferation, oxidative stress, and cell death. We employed blue light illumination on human umbilical vein endothelial cells utilizing a LED device at 453 nm wavelength and revealed
Externí odkaz:
https://doaj.org/article/6f5490076c034ed7bb2fcaa25b7dff7a
Autor:
Rilu Feng, Kejia Kan, Carsten Sticht, Yujia Li, Shanshan Wang, Hui Liu, Chen Shao, Stefan Munker, Hanno Niess, Sai Wang, Christoph Meyer, Roman Liebe, Matthias P. Ebert, Steven Dooley, Huiguo Ding, Honglei Weng
Publikováno v:
Hepatology. 76:1673-1689
It remains unknown how patients with liver failure maintain essential albumin levels. Here, we delineate a hierarchical transcription regulatory network that ensures albumin expression under different disease conditions.We examined albumin levels in
Autor:
Rilu Feng, Chenhao Tong, Tao Lin, Hui Liu, Chen Shao, Yujia Li, Carsten Sticht, Kejia Kan, Xiaofeng Li, Rui Liu, Sai Wang, Shanshan Wang, Stefan Munker, Hanno Niess, Christoph Meyer, Roman Liebe, Matthias P Ebert, Steven Dooley, Hua Wang, Huiguo Ding, Hong-Lei Weng
To date, epithelial-to-mesenchymal transition (EMT) has been observed in cultured hepatocytes, but notin vivo. TGF-β is supposed to initiate EMT in hepatocytes by inhibiting HNF4αthrough the SMAD2/3 complex. We report that TGF-βdoes not directly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bebade5eb3937cfbc1bd091755fd6b
https://doi.org/10.1101/2023.01.12.523351
https://doi.org/10.1101/2023.01.12.523351
Autor:
Rilu Feng, Rui Liu, Chenhao Tong, Tao Lin, Xiaofeng Li, Hui Liu, Chen Shao, Kejia Kan, Carsten Sticht, Yujia Li, Sai Wang, Stefan Munker, Hanno Niess, Roman Liebe, Christoph Meyer, Shanshan Wang, Matthias P. Ebert, Steven Dooley, Huiguo Ding, Hua Wang, Honglei Weng
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.