Zobrazeno 1 - 10
of 593
pro vyhledávání: '"Kejal, Kantarci"'
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Annegret Habich, Javier Oltra, Christopher G. Schwarz, Scott A. Przybelski, Ketil Oppedal, Anna Inguanzo, Frédéric Blanc, Afina W. Lemstra, Jakub Hort, Eric Westman, Barbara Segura, Carme Junque, Val J. Lowe, Bradley F. Boeve, Dag Aarsland, Thomas Dierks, Kejal Kantarci, Daniel Ferreira
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Sex differences permeate many aspects of dementia with Lewy bodies (DLB), yet sex differences in patterns of neurodegeneration in DLB remain largely unexplored. Here, we test whether grey matter networks differ between sexes in DLB and compa
Externí odkaz:
https://doaj.org/article/4192cd84086d42c4a0564db083b04590
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Autor:
Xi Yu, Scott A. Przybelski, Robert I. Reid, Timothy G. Lesnick, Sheelakumari Raghavan, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr., Prashanthi Vemuri
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Age‐related and Alzheimer's disease (AD) dementia–related neurodegeneration impact brain health. While morphometric measures from T1‐weighted scans are established biomarkers, they may be less sensitive to earlier changes.
Externí odkaz:
https://doaj.org/article/68f17f5c04e049068a8e8c8632f60d2c
Autor:
Firat Kara, Kejal Kantarci
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10064 (2024)
In vivo proton (1H) magnetic resonance spectroscopy (MRS) is a powerful non-invasive method that can measure Alzheimer’s disease (AD)-related neuropathological alterations at the molecular level. AD biomarkers include amyloid-beta (Aβ) plaques and
Externí odkaz:
https://doaj.org/article/bfba6316c6554f659fb1a7ed919443d0
Autor:
Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Jr, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci, Jennifer L. Whitwell
Publikováno v:
NeuroImage, Vol 290, Iss , Pp 120564- (2024)
Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) show distinct atrophy and overlapping hypometabolism profiles, but it is unknown how disruptions in structural and functional connectivity compare between these disorders and whethe
Externí odkaz:
https://doaj.org/article/c9523c15658b48e5b201ae474cbd48e7
Autor:
Da Ma, Jane Stocks, Howard Rosen, Kejal Kantarci, Samuel N. Lockhart, James R. Bateman, Suzanne Craft, Metin N. Gurcan, Karteek Popuri, Mirza Faisal Beg, Lei Wang, on behalf of the ALLFTD consortium
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundFrontotemporal dementia (FTD) represents a collection of neurobehavioral and neurocognitive syndromes that are associated with a significant degree of clinical, pathological, and genetic heterogeneity. Such heterogeneity hinders the identif
Externí odkaz:
https://doaj.org/article/b48b2d2eb6b14e8e84f5d1a9b34a4ee3
Autor:
Silvia De Francesco, Claudio Crema, Damiano Archetti, Cristina Muscio, Robert I. Reid, Anna Nigri, Maria Grazia Bruzzone, Fabrizio Tagliavini, Raffaele Lodi, Egidio D’Angelo, Brad Boeve, Kejal Kantarci, Michael Firbank, John-Paul Taylor, Pietro Tiraboschi, Alberto Redolfi, the RIN – Neuroimaging Network
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Biomarker-based differential diagnosis of the most common forms of dementia is becoming increasingly important. Machine learning (ML) may be able to address this challenge. The aim of this study was to develop and interpret a ML algorithm ca
Externí odkaz:
https://doaj.org/article/91157c153dca4a119207f9be522c5142
Autor:
Patricia Diaz-Galvan, Giulia Lorenzon, Rosaleena Mohanty, Gustav Mårtensson, Enrica Cavedo, Simone Lista, Andrea Vergallo, Kejal Kantarci, Harald Hampel, Bruno Dubois, Michel J. Grothe, Daniel Ferreira, Eric Westman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Donepezil is an approved therapy for the treatment of Alzheimer’s disease (AD). Results across clinical trials have been inconsistent, which may be explained by design-methodological issues, the pathophysiological heterogeneity
Externí odkaz:
https://doaj.org/article/c3cc3689759d4049ac3b5074cde45ab8
Autor:
Nick Corriveau-Lecavalier, Leland R. Barnard, Scott A. Przybelski, Venkatsampath Gogineni, Hugo Botha, Jonathan Graff-Radford, Vijay K. Ramanan, Leah K. Forsberg, Julie A. Fields, Mary M. Machulda, Rosa Rademakers, Ralitza H. Gavrilova, Maria I. Lapid, Bradley F. Boeve, David S. Knopman, Val J. Lowe, Ronald C. Petersen, Clifford R. Jack, Kejal Kantarci, David T. Jones
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103559- (2024)
Genetic mutations causative of frontotemporal lobar degeneration (FTLD) are highly predictive of a specific proteinopathy, but there exists substantial inter-individual variability in their patterns of network degeneration and clinical manifestations
Externí odkaz:
https://doaj.org/article/70c787dd63d643fea9b1dbdf0ec4a2cf