Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Keizo Hiraishi"'
Autor:
Feiyan Zhao, Keizo Hiraishi, Xiaodong Li, Yaopeng Hu, Daibo Kojima, Zhihong Sun, Heping Zhang, Lin-Hai Kurahara
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 531 (2024)
Intestinal bacteria play important roles in the progression of colitis-associated carcinogenesis. Colostrum-derived Lacticaseibacillus rhamnosus Probio-M9 (Probio-M9) has shown a protective effect in a colitis-associated cancer (CAC) model, but detai
Externí odkaz:
https://doaj.org/article/9a794328b85b42c08c7445593a98e1c2
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11798 (2023)
The transient receptor potential melastatin 4 (TRPM4) channel is a non-selective cation channel that activates in response to increased intracellular Ca2+ levels but does not allow Ca2+ to pass through directly. It plays a crucial role in regulating
Externí odkaz:
https://doaj.org/article/e93cbaf8a6d848a3894cb55ed43bdf46
Autor:
Keizo Hiraishi, Feiyan Zhao, Lin-Hai Kurahara, Xiaodong Li, Tetsuo Yamashita, Takeshi Hashimoto, Yoko Matsuda, Zhihong Sun, Heping Zhang, Katsuya Hirano
Publikováno v:
Nutrients, Vol 14, Iss 3, p 649 (2022)
Lactulose, a galactose-fructose disaccharide, is made from the milk sugar lactose by heating or isomerization processes. Lactulose is proposed to modulate gut microbiota and thus expected to be beneficial in treating inflammatory bowel disease. In th
Externí odkaz:
https://doaj.org/article/fe07f7762ba549b48b009ac93c8cc723
Autor:
Lin Hai Kurahara, Keizo Hiraishi, Yaopeng Hu, Kaori Koga, Miki Onitsuka, Mayumi Doi, Kunihiko Aoyagi, Hidetoshi Takedatsu, Daibo Kojima, Yoshitaka Fujihara, Yuwen Jian, Ryuji Inoue
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 299-318 (2018)
The transient receptor potential ankyrin 1 (TRPA1) channel is highly expressed in the intestinal lamina propria, but its contribution to gut physiology/pathophysiology is unclear. Here, we evaluated the function of myofibroblast TRPA1 channels in int
Externí odkaz:
https://doaj.org/article/1438c7fd8366470181e1e4170290e1e2
Autor:
Yaopeng Hu, Qin Li, Lin-Hai Kurahara, Narumi Shioi, Keizo Hiraishi, Takayuki Fujita, Xin Zhu, Ryuji Inoue
Publikováno v:
Cells, Vol 10, Iss 5, p 983 (2021)
A Ca2+-activated monovalent cation-selective TRPM4 channel is abundantly expressed in the heart. Recently, a single gain-of-function mutation identified in the distal N-terminus of the human TRPM4 channel (Glu5 to Lys5; E7K) was found to be arrhythmo
Externí odkaz:
https://doaj.org/article/75beb3bccd61441790ac3853e474498e
Autor:
Haiyan Xu, Keizo Hiraishi, Lin-Hai Kurahara, Yuko Nakano-Narusawa, Xiaodong Li, Yaopeng Hu, Yoko Matsuda, Heping Zhang, Katsuya Hirano
Publikováno v:
Nutrients, Vol 13, Iss 4, p 1143 (2021)
Chronic inflammation is a risk factor for colorectal cancer, and inflammatory cytokines secreted from inflammatory cells and active oxygen facilitate tumorigenesis. Intestinal bacteria are thought to regulate tumorigenesis. The longer the breastfeedi
Externí odkaz:
https://doaj.org/article/6014beae2ff64f019ccaf3ea71d1e1e9
Autor:
Keizo, Hiraishi, Lin Hai, Kurahara, Kaori, Ishikawa, Tetsuhiko, Go, Naoya, Yokota, Yaopeng, Hu, Takayuki, Fujita, Ryuji, Inoue, Katsuya, Hirano
Publikováno v:
Journal of Smooth Muscle Research. 58:50-62
Pulmonary arterial hypertension (PAH) is an intractable vascular disease characterized by a progressive increase in pulmonary vascular resistance caused by pulmonary vascular remodeling, which ultimately leads to right-sided heart failure. PAH remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fb8c8b41f09b7d7e82624d6f0406ef
https://doi.org/10.1540/jsmr.58.50
https://doi.org/10.1540/jsmr.58.50
Autor:
Masafumi Takahashi, Masatoshi Hori, Wataru Suto, Yoshihiko Chiba, Yuki Kai, Fumitake Usui-Kawanishi, Lin Hai Kurahara, Keizo Hiraishi, Hiroyasu Sakai, Ryuji Inoue
Publikováno v:
Journal of Smooth Muscle Research
In the past few decades, solid evidence has been accumulated for the pivotal significance of immunoinflammatory processes in the initiation, progression, and exacerbation of many diseases and disorders. This groundbreaking view came from original wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1791e6ecb7a3237bc3ed9b3f333cae20
https://doi.org/10.1540/jsmr.55.81
https://doi.org/10.1540/jsmr.55.81
Autor:
Kaori Koga, Tetsuhiko Go, Mikiko Aoki, Ryuji Inoue, Hiroyasu Yokomise, Aya Yamamura, Kohtaro Abe, Katsuya Hirano, Lin Hai Kurahara, Narumi Aoki-Shoi, Sei Kobayashi, Eiji Yahiro, Satoh Toru, Hiroko Kishi, Keizo Hiraishi, Zhang Bo, Kaori Ishikawa, Ying Zhang
Publikováno v:
Journal of Molecular and Cellular Cardiology. 148:50-62
Pulmonary arterial hypertension (PAH) is a multifactorial disease characterized by pulmonary arterial vasoconstriction and remodeling. Src family tyrosine kinases, including Fyn, play critical roles in vascular remodeling via the inhibition of STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0124da393ce7dfdf1b9d5a2303ff43c6
https://doi.org/10.1016/j.yjmcc.2020.08.013
https://doi.org/10.1016/j.yjmcc.2020.08.013
Autor:
Heping Zhang, Yaopeng Hu, Yuko Nakano-Narusawa, Xiaodong Li, Katsuya Hirano, Haiyan Xu, Keizo Hiraishi, Yoko Matsuda, Lin-Hai Kurahara
Publikováno v:
Nutrients
Volume 13
Issue 4
Nutrients, Vol 13, Iss 1143, p 1143 (2021)
Volume 13
Issue 4
Nutrients, Vol 13, Iss 1143, p 1143 (2021)
Chronic inflammation is a risk factor for colorectal cancer, and inflammatory cytokines secreted from inflammatory cells and active oxygen facilitate tumorigenesis. Intestinal bacteria are thought to regulate tumorigenesis. The longer the breastfeedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23287ef37fc7b2c78ac217d02b4093e