Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Keizer, H J"'
Autor:
Keizer, H. J., van Putten, L. M.
Publikováno v:
Radiation Research, 1976 May 01. 66(2), 326-336.
Externí odkaz:
https://www.jstor.org/stable/3574400
Autor:
Steyerberg, E. W., Keizer, H. J., Fosså, S. D., Sleijfer, D. T., Bajorin, D. F., Donohue, J. P., Habbema, J. D.
Publikováno v:
British Journal of Cancer
Residual retroperitoneal masses may remain after chemotherapy for metastatic non-seminomatous testicular cancer, which harbour residual tumour or totally benign tissue (necrosis/fibrosis). These residual masses may be effectively removed by a surgica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e80536495ee4276b672266231f70a117
http://europepmc.org/articles/PMC2074767
http://europepmc.org/articles/PMC2074767
Autor:
Delft, J. H. M., Luiten-Schuite, A., Souliotis, V. L., Soterios Kyrtopoulos, Ouwerkerk, J., Keizer, H. J., Baan, R. A.
Publikováno v:
Biomarkers 1:2(Apr-Jun1996):94-98
Biomarkers, 2, 1, 94-98
Scopus-Elsevier
Biomarkers, 2, 1, 94-98
Scopus-Elsevier
Methyl-DNA adducts are induced by a number of lifestyle, environmental and occupational carcinogens, however knowledge about their kinetics is scarce. Here, N7-methylguanine (N7-MeGua) and O6-methylguanine (O6-MeGua) levels were determined in the DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c5a395e0372db41305a11bb00b1d8510
http://helios-eie.ekt.gr/EIE/handle/10442/2733
http://helios-eie.ekt.gr/EIE/handle/10442/2733
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals, 29(7), 967-975. American Society for Pharmacology and Experimental Therapeutics
The anticancer drug ifosfamide is a prodrug requiring activation through 4-hydroxyifosfamide to ifosforamide mustard, to exert cytotoxicity. Deactivation of ifosfamide leads to 2- and 3-dechloroethylifosfamide and the release of potentially neurotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::cacfb1f8dc5ab4d75d07fe901096af16
https://pure.amc.nl/en/publications/influence-of-dose-and-infusion-duration-on-pharmacokinetics-of-ifosfamide-and-metabolites(2bffd985-9d38-40f4-ac53-9089590ed3bb).html
https://pure.amc.nl/en/publications/influence-of-dose-and-infusion-duration-on-pharmacokinetics-of-ifosfamide-and-metabolites(2bffd985-9d38-40f4-ac53-9089590ed3bb).html
Autor:
Reichardt, P., van Glabbeke, M., Mourudsen, H., Verweij, J., Radford, J., Rodenhuis, S., Azzarelli, A., Le Cesne, A., Buesa, J., Keizer, H. J., van Oosterom, A., Kirkpatrick, A., Nielsen, Ole Steen
Publikováno v:
Reichardt, P, van Glabbeke, M, Mourudsen, H, Verweij, J, Radford, J, Rodenhuis, S, Azzarelli, A, Le Cesne, A, Buesa, J, Keizer, H J, van Oosterom, A, Kirkpatrick, A & Nielsen, O S 2000, ' Influence of locally advanced and recurrent disease on survival of patients with advanced soft tissue sarcomas. A retrospective analysis of the eortc soft tissue and bone sarcoma group. ', Sarcoma .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::05406fc5ddeffa9230a8e44eb86ec7f9
https://pure.au.dk/portal/da/publications/influence-of-locally-advanced-and-recurrent-disease-on-survival-of-patients-with-advanced-soft-tissue-sarcomas-a-retrospective-analysis-of-the-eortc-soft-tissue-and-bone-sarcoma-group(9a53491a-12df-4c4b-bf91-b98803c66f4d).html
https://pure.au.dk/portal/da/publications/influence-of-locally-advanced-and-recurrent-disease-on-survival-of-patients-with-advanced-soft-tissue-sarcomas-a-retrospective-analysis-of-the-eortc-soft-tissue-and-bone-sarcoma-group(9a53491a-12df-4c4b-bf91-b98803c66f4d).html
Autor:
van Glabbeke, M., Le Cesne, A., Radford, J., Verweij, J., Mouridsen, H. T., Rodenhuis, S., Keizer, H. J., Kirkpatrick, A., Nielsen, Ole Steen
Publikováno v:
van Glabbeke, M, Le Cesne, A, Radford, J, Verweij, J, Mouridsen, H T, Rodenhuis, S, Keizer, H J, Kirkpatrick, A & Nielsen, O S 2000, ' Late responders to first line chemotherapy for advanced or metastatic soft tissue sarcoma have a longer survival than early responders. A retrospective analysis of the EORTC Soft Tissue and Bone Sarcoma Group. ', Journal of Clinical Oncology .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::4b812e8c18cb3f79063e95c21cdacb9a
https://pure.au.dk/portal/da/publications/late-responders-to-first-line-chemotherapy-for-advanced-or-metastatic-soft-tissue-sarcoma-have-a-longer-survival-than-early-responders-a-retrospective-analysis-of-the-eortc-soft-tissue-and-bone-sarcoma-group(cdd0f568-14f5-4836-9d23-f2581d4d6482).html
https://pure.au.dk/portal/da/publications/late-responders-to-first-line-chemotherapy-for-advanced-or-metastatic-soft-tissue-sarcoma-have-a-longer-survival-than-early-responders-a-retrospective-analysis-of-the-eortc-soft-tissue-and-bone-sarcoma-group(cdd0f568-14f5-4836-9d23-f2581d4d6482).html
Autor:
Vahrmeijer, A L, van Dierendonck, J H, Keizer, H J, Beijnen, J H, Tollenaar, R A E M, Pijl, M E J, Marinelli, A, Kuppen, P J K, van Bockel, J H, Mulder, G J, Velde, C J H van de
Publikováno v:
British Journal of Cancer, 82(9), 1539-1546. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
A phase I dose-escalation study was performed to determine whether isolated hepatic perfusion (IHP) with melphalan (L-PAM) allows exposure of the liver to much higher drug concentrations than clinically achievable after systemic administration and le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb6c34f1b7900db227bb15d897b511f8
https://pure.eur.nl/en/publications/cc66f9af-99a8-40b7-ae42-103df302e3bc
https://pure.eur.nl/en/publications/cc66f9af-99a8-40b7-ae42-103df302e3bc
Autor:
Kerbusch, T., Huitema, A. D., Ouwerkerk, J., Keizer, H. J., Mathôt, R. A., Schellens, J. H., Beijnen, J. H.
Publikováno v:
British journal of clinical pharmacology, 49(6), 555-561. Wiley-Blackwell
This study investigated the population pharmacokinetics of ifosfamide in 15 patients treated for soft tissue sarcoma with 9 or 12 g m-2 ifosfamide by means of a 72 h continuous i.v. infusion. A model was developed using nonlinear mixed effects modell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::c43a5865e77881f57a79400ab2382106
https://pure.amc.nl/en/publications/evaluation-of-the-autoinduction-of-ifosfamide-metabolism-by-a-population-pharmacokinetic-approach-using-nonmem(ae444dc8-6903-4568-9b20-1cc4ca570b38).html
https://pure.amc.nl/en/publications/evaluation-of-the-autoinduction-of-ifosfamide-metabolism-by-a-population-pharmacokinetic-approach-using-nonmem(ae444dc8-6903-4568-9b20-1cc4ca570b38).html
Autor:
Keizer, H. J., Crowther, D., Nielsen, Ole Steen, van Oosterom, A. T., Hornedo Muguiro, J., van Pottelberghe, C., Somers, R., Tursz, T.
Publikováno v:
Keizer, H J, Crowther, D, Nielsen, O S, van Oosterom, A T, Hornedo Muguiro, J, van Pottelberghe, C, Somers, R & Tursz, T 1997, ' Twenty-one days of oral etoposide in a 4-weeks schedule for pre-treated soft tissuse sarcoma: A phase II study of the EORTC Soft Tissue and Bone Sarcoma Groups ', Sarcoma, vol. 1, pp. 99-102 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::b633586b7d1436f6c878f07c0000a691
https://pure.au.dk/portal/da/publications/twentyone-days-of-oral-etoposide-in-a-4weeks-schedule-for-pretreated-soft-tissuse-sarcoma-a-phase-ii-study-of-the-eortc-soft-tissue-and-bone-sarcoma-groups(070d4e2c-8532-4702-a370-67bf71173758).html
https://pure.au.dk/portal/da/publications/twentyone-days-of-oral-etoposide-in-a-4weeks-schedule-for-pretreated-soft-tissuse-sarcoma-a-phase-ii-study-of-the-eortc-soft-tissue-and-bone-sarcoma-groups(070d4e2c-8532-4702-a370-67bf71173758).html
Publikováno v:
European Spine Journal; Apr2006, Vol. 15 Issue 4, p472-478, 7p, 4 Charts