Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Keiya Nakajima"'
Autor:
Jeff A. Johnson, Giridhar Athrey, Clifford M. Anderson, Douglas A. Bell, Andrew Dixon, Yoshinori Kumazawa, Tom Maechtle, Garrett W. Meeks, David Mindell, Keiya Nakajima, Ben Novak, Sandra Talbot, Clayton White, Xiangjiang Zhan
Publikováno v:
Ecology and Evolution, Vol 13, Iss 7, Pp n/a-n/a (2023)
Abstract In efforts to prevent extinction, resource managers are often tasked with increasing genetic diversity in a population of concern to prevent inbreeding depression or improve adaptive potential in a changing environment. The assumption that a
Externí odkaz:
https://doaj.org/article/0e5daedba6364d87956e39c45af6294d
Publikováno v:
Experimental Neurology. 164:209-214
Epidermal growth factor (EGF)/fibroblast growth factor (FGF)-responsive stem (progenitor) cells from embryonic brain have self-renewing and multipotent properties and thus are good candidates for donor cells in neural transplantation. However, the su
Autor:
Yasunobu Shimano, Hitoo Nishino, Takeshi Hashitani, Atsuo Fukuda, Ichiro Fujimoto, Keiya Nakajima, Hideki Hida
Publikováno v:
Neuroscience Research. 28:209-221
To evaluate the possibility that dopamine (DA) denervation enhances the trophic activity in striatum, normal or DA-depleted striatal tissue extract (N- or L-extract, respectively) was obtained, and their trophic effects on PC12D cells were investigat
Autor:
Akihito Okabe, Hideki Hida, Keiya Nakajima, Ichiro Fujimoto, Hitoo Nishino, Atsuo Fukuda, Yasunobu Shimano
Publikováno v:
Neuroscience Letters. 205:193-196
The effects of tissue extract from dopamine (DA)-depleted striatum (lesion extract, L-ext) on morphological and electrophysiological natures of cultured striatal astrocytes were investigated. L-ext treatment suppressed the proliferation of type-1 ast
Autor:
Hideki Hida, Ichiro Fujimoto, Takeshi Hashitani, Michiko Kumazaki, Terumi Sakurai, Yasunobu Shimano, Hitoo Nishino, Keiya Nakajima
Publikováno v:
Brain research. 916(1-2)
Extracts from dopamine (DA)-depleted striatal tissue (lesion extract) and from intact striatal tissue (intact extract) were prepared, and trophic activities in these extracts were evaluated using survival and neurite extension of DAergic neurons as i
Autor:
Hideo Shimizu, Hideki Hida, Keiya Nakajima, Yasunobu Shimano, Takanori Ooiwa, Hiroko Baba, Michiko Kumazaki, Hitoo Nishino
Publikováno v:
Journal of neurotrauma. 17(3)
The striatum, together with the hippocampus, is one of the most vulnerable regions in the brain. Recently, genetic abnormalities or mutations have been linked to various neurodegenerative diseases, that is, Huntington's disease, Alzheimer's disease,
Autor:
Hideki Hida, Katsuhiko Mikoshiba, Yasunobu Shimano, Toshiharu Nagatsu, Keiya Nakajima, Hitoo Nishino, Mitsuhiro Hashimoto, Ichiro Fujimoto
Publikováno v:
Neuroscience research. 35(2)
Astrocytes secreting a large amount of 3,4-dihydroxyphenylalanine (dopa) were generated by adenoviral transduction of the human tyrosine hydroxylase (TH) gene. After characterizing in vitro, the effect of transplantation of these astrocytes to the st
Publikováno v:
Mitochondrial Inhibitors and Neurodegenerative Disorders ISBN: 9781468498219
Systemic intoxication of rats with 3-nitropropionic acid (3-NPA), a mycotoxin that inhibits succinate dehydrogenase in the mitochondrial respiratory chain, induces the striatum-selective lesions and motor symptoms (hyperkinesia, rolling, paddling, hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d75c3809e40d7242a292e2bf6d1092
https://doi.org/10.1007/978-1-59259-692-8_8
https://doi.org/10.1007/978-1-59259-692-8_8
Autor:
Kanji Muramatsu, Paul R. Sanberg, Toshiro Inubushi, Hitoo Nishino, Atsuo Fukuda, Michiko Kumazaki, Cesario V. Borlongan, Shigehiro Morikawa, Keiya Nakajima, Shripad B. Deshpande
Publikováno v:
Neuroscience research. 30(4)
Gender differences in the vulnerability of the lateral striatal artery (1STR artery) to systemic intoxication with 3-nitropropionic acid (3-NPA, succinate dehydrogenase inhibitor) were studied. Subcutaneous injection of 3-NPA (20 mg/kg once a day for
Autor:
Hitoo Nishino, Hideki Hida, Atsuo Fukuda, Michiko Kumazaki, Kanji Muramatsu, Ichiro Fujimoto, Keiichiro Onizuka, Keiya Nakajima, Yasunobu Shimano
Publikováno v:
Experimental neurology. 137(2)
Physiological properties of grafted neurons, such as membrane and intracellular properties, have not been reported. To fill this lack in knowledge, physiological recordings from the identified grafted cells are required. Fluorescent latex microsphere