Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Keivan, Zandi"'
Autor:
Selwyn J. Hurwitz, Ramyani De, Julia C. LeCher, Jessica A. Downs-Bowen, Shu Ling Goh, Keivan Zandi, Tamara McBrayer, Franck Amblard, Dharmeshkumar Patel, James J. Kohler, Manoj Bhasin, Brian S. Dobosh, Vikas Sukhatme, Rabindra M. Tirouvanziam, Raymond F. Schinazi
Publikováno v:
Viruses, Vol 16, Iss 4, p 651 (2024)
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical trials, in Vero cells. Ratios of reported unbound peak plasma concentr
Externí odkaz:
https://doaj.org/article/954d72f36177427d91cc4fd8c5a0b6f5
Autor:
Javad Charostad, Mohammad Rezaei Zadeh Rukerd, Shahab Mahmoudvand, Davood Bashash, Seyed Mohammad Ali Hashemi, Mohsen Nakhaie, Keivan Zandi
Publikováno v:
Travel Medicine and Infectious Disease, Vol 55, Iss , Pp 102638- (2023)
Avian influenza viruses (AIVs) are globally challenging due to widespread circulation and high mortality rates. Highly pathogenic avian influenza (HPAI) strains like H5N1 have caused significant outbreaks in birds. Since 2003 to 14 July 2023, the Wor
Externí odkaz:
https://doaj.org/article/62fe3bfd1af9432180c80c9b59edf391
Autor:
Caitlin J. Risener, Sunmin Woo, Tharanga Samarakoon, Marco Caputo, Emily Edwards, Kier Klepzig, Wendy Applequist, Keivan Zandi, Shu Ling Goh, Jessica A. Downs-Bowen, Raymond F. Schinazi, Cassandra L. Quave
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Throughout the SARS-CoV-2 pandemic, the use of botanical dietary supplements in the United States has increased, yet their safety and efficacy against COVID-19 remains underexplored. The Quave Natural Product Library is a phylogenetically di
Externí odkaz:
https://doaj.org/article/d89e5d532e364884918b98090f61e305
Autor:
Brian Dobosh, Keivan Zandi, Diego Moncada Giraldo, Shu Ling Goh, Kathryn Musall, Milagros Aldeco, Julia LeCher, Vincent D. Giacalone, Junkai Yang, Devon J. Eddins, Manoj Bhasin, Eliver Ghosn, Vikas Sukhatme, Raymond F. Schinazi, Rabindra Tirouvanziam
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110945- (2022)
Summary: SARS-CoV-2-infected subjects are generally asymptomatic during initial viral replication but may suffer severe immunopathology after the virus has receded and monocytes have infiltrated the airways. In bronchoalveolar lavage fluid from sever
Externí odkaz:
https://doaj.org/article/ea7bd0ec72344e9d92d16f88c63dabad
Autor:
Boon-Teong Teoh, Kim-Ling Chin, Nur-Izyan Samsudin, Shih-Keng Loong, Sing-Sin Sam, Kim-Kee Tan, Chee-Sieng Khor, Juraina Abd-Jamil, Nurhafiza Zainal, Annelies Wilder-Smith, Keivan Zandi, Sazaly AbuBakar
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Early detection of Zika virus (ZIKV) infection during the viremia and viruria facilitates proper patient management and mosquito control measurement to prevent disease spread. Therefore, a cost-effective nucleic acid detection met
Externí odkaz:
https://doaj.org/article/653c30748834476d84eb8e000c12a0a5
Autor:
Razieh Sadat Banijamali, Hoorieh Soleimanjahi, Sara Soudi, Hesam Karimi, Asghar Abdoli, Seyed Mahmood Seyed Khorrami, Keivan Zandi
Publikováno v:
Cell Journal, Vol 22, Iss 3, Pp 283-292 (2020)
Objective: Currently, application of oncolytic-virus in cancer treatment of clinical trials are growing. Oncolytic-reovirus is an attractive anti-cancer therapeutic agent for clinical testing. Many studies used mesenchymal stem cells (MSCs) as a ca
Externí odkaz:
https://doaj.org/article/b601e2457f7a461c970b0f1ec228d450
Autor:
Julia C. LeCher, Keivan Zandi, Vivian Vasconcelos Costa, Franck Amblard, Sijia Tao, Dharmeshkumar Patel, Sujin Lee, Felipe Rocha da Silva Santos, Matheus Rodrigues Goncalves, Celso Martins Queroz-Junior, Fernanda Martins Marim, Katie Musall, Shu Ling Goh, Tamara McBrayer, Jessica Downs-Bowen, Ramyani De, Niloufar Azadi, James Kohler, Mauro Martins Teixeira, Raymond F. Schinazi
Publikováno v:
Microorganisms, Vol 10, Iss 11, p 2098 (2022)
Yellow fever virus (YFV) is a potentially lethal, zoonotic, blood-borne flavivirus transmitted to humans and non-human primates by mosquitoes. Owing to multiple deadly epidemics, the WHO classifies YFV as a “high impact, high threat disease” with
Externí odkaz:
https://doaj.org/article/b7afa49fb6e74c87b2b2be789d66b3e8
Autor:
Franck Amblard, Julia C. LeCher, Ramyani De, Shu Ling Goh, Chengwei Li, Mahesh Kasthuri, Nicolas Biteau, Longhu Zhou, Zahira Tber, Jessica Downs-Bowen, Keivan Zandi, Raymond F. Schinazi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1144 (2022)
Coronavirus disease 2019 (COVID-19) is an emerging global pandemic with severe morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molnupiravir, an ester prodrug form of N4-hydroxycytidine (NHC), was re
Externí odkaz:
https://doaj.org/article/5b28f39250b449959a136cc3c1d06f07
Autor:
Sijia Tao, Keivan Zandi, Leda Bassit, Yee Tsuey Ong, Kiran Verma, Peng Liu, Jessica A. Downs-Bowen, Tamara McBrayer, Julia C. LeCher, James J. Kohler, Philip R. Tedbury, Baek Kim, Franck Amblard, Stefan G. Sarafianos, Raymond F. Schinazi
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100045- (2021)
Remdesivir, a monophosphate prodrug of nucleoside analog GS-441524, is widely used for the treatment of moderate to severe COVID-19. It has been suggested to use GS-441524 instead of remdesivir in the clinic and in new inhalation formulations. Thus,
Externí odkaz:
https://doaj.org/article/d94330ccb3e0445a8d9165b90ad608da
Autor:
Eloïne Bestion, Keivan Zandi, Sandrine Belouzard, Julien Andreani, Hubert Lepidi, Marie Novello, Clara Rouquairol, Jean-Pierre Baudoin, Madani Rachid, Bernard La Scola, Jean-Louis Mege, Jean Dubuisson, Raymond F. Schinazi, Soraya Mezouar, Philippe Halfon
Publikováno v:
Viruses, Vol 14, Iss 1, p 132 (2022)
Since December 2019, SARS-CoV-2 has spread quickly worldwide, leading to more than 280 million confirmed cases, including over 5,000,000 deaths. Interestingly, coronaviruses were found to subvert and hijack autophagic process to allow their viral rep
Externí odkaz:
https://doaj.org/article/62874bdbbb2a4425ae2a44915973e2a8