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Autor:
David Clifford, John R. Williams, Terry V. Silk, Christopher P. Ashcroft, Nicholas Murray Thomson, Yousef Hajikarimian, Andrew Derrick, Keith Slucock, Stephen Challenger
Publikováno v:
Organic Process Research & Development. 9:663-669
The development and scale-up of a potential manufacturing route to the endothelin antagonists UK-350,926 1 and UK-349,862 2 are described. A key synthetic challenge in designing an efficient route ...