Zobrazeno 1 - 10
of 564
pro vyhledávání: '"Keith S, Kaye"'
Autor:
Keith S. Kaye, Vikas Gupta, Aruni Mulgirigama, Ashish V. Joshi, Nicole E. Scangarella-Oman, Kalvin Yu, Janet Watts, Fanny S. Mitrani-Gold
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 7, Pp 1715-1722 (2024)
Abstract Introduction Urinary tract infections (UTIs) caused by antimicrobial-resistant Enterobacterales are a global health threat. There are limited surveillance data available to characterize the prevalence of antimicrobial resistance among outpat
Externí odkaz:
https://doaj.org/article/434acad0f0cd4110bfa2d1febb5851c3
Autor:
Keith S. Kaye, Vikas Gupta, Aruni Mulgirigama, Ashish V. Joshi, Gang Ye, Nicole E. Scangarella-Oman, Kalvin Yu, Fanny S. Mitrani-Gold
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 13, Iss 1, Pp 1-9 (2024)
Abstract Background Antimicrobial resistance research in uncomplicated urinary tract infection typically focuses on the main causative pathogen, Escherichia coli; however, little is known about the antimicrobial resistance burden of Klebsiella specie
Externí odkaz:
https://doaj.org/article/8fa9c8c3316e4a999f0337d34a28fd5a
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 3, Pp 777-806 (2023)
Abstract Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat, and, despite recent approvals, new antibiotics are needed. Severe infections caused by CRE, such as nosocomial pneumonia and bloodstream infections, are a
Externí odkaz:
https://doaj.org/article/c7021e66e5c541dab2566cd10a710df0
Autor:
Jacinda C. Abdul-Mutakabbir, Nana Sakyi Opoku, Karen K. Tan, Peter Jorth, Victor Nizet, Hansel M. Fletcher, Keith S. Kaye, Michael J. Rybak
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 47 (2024)
With the increase in carbapenem-resistant A. baumannii (CRAB) infections, there has been a resurgence in the use of polymyxins, specifically colistin (COL). Since the reintroduction of COL-based regimens in treating CRAB infections, several COL-resis
Externí odkaz:
https://doaj.org/article/5ae6b67e3cb44ec99d3e65c898a57272
Autor:
Jay Vornhagen, Emily K. Roberts, Lavinia Unverdorben, Sophia Mason, Alieysa Patel, Ryan Crawford, Caitlyn L. Holmes, Yuang Sun, Alexandra Teodorescu, Evan S. Snitkin, Lili Zhao, Patricia J. Simner, Pranita D. Tamma, Krishna Rao, Keith S. Kaye, Michael A. Bachman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patient variables, such as comorbidities, partially explain which patients will progress to Klebsiella infection, with colonization of the gut acting as a reservoir. Little is known, however, regarding Klebsiella genes that may increase risk of disea
Externí odkaz:
https://doaj.org/article/9fca71bb880145e79855025ffb4001fa
Autor:
Hadas Kon, Amichay Hameir, Amir Nutman, Elizabeth Temkin, Alona Keren Paz, Jonathan Lellouche, David Schwartz, David S. Weiss, Keith S. Kaye, George L. Daikos, Anna Skiada, Emanuele Durante-Mangoni, Yael Dishon Benattar, Dafna Yahav, Vered Daitch, Mariano Bernardo, Domenico Iossa, Lena E. Friberg, Ursula Theuretzbacher, Leonard Leibovici, Yaakov Dickstein, Dina Pollak, Sigal Mendelsohn, Mical Paul, Yehuda Carmeli
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Colistin heteroresistance (HR) refers to a bacterial population comprised of several subpopulations with different levels of resistance to colistin. In this study, we discuss the classic form of HR, in which a resistant subpopulation exists
Externí odkaz:
https://doaj.org/article/942905d3087940cfab019bebdcc8a64f
Autor:
Fanny S Mitrani-Gold, Keith S Kaye, Vikas Gupta, Aruni Mulgirigama, Barbara W Trautner, Nicole E Scangarella-Oman, Kalvin C Yu, Gang Ye, Ashish V Joshi
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285427 (2023)
BackgroundIncreasing prevalence of antimicrobial resistance (AMR), including multidrug resistance (MDR), among Escherichia coli (E. coli) makes treatment of uncomplicated urinary tract infection (uUTI) difficult. We assessed risk factors for fluoroqu
Externí odkaz:
https://doaj.org/article/af446e761b8446f7b1bfed9dd42af206
Autor:
Patrick O. Hanafin, Roger L. Nation, Marc H. Scheetz, Alexandre P. Zavascki, Ana M. Sandri, Andrea L. Kwa, Benjamin P. Z. Cherng, Christine J. Kubin, Michael T. Yin, Jiping Wang, Jian Li, Keith S. Kaye, Gauri G. Rao
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1525-1537 (2021)
Abstract Polymyxin B (PMB) has reemerged as a last‐line therapy for infections caused by multidrug‐resistant gram‐negative pathogens, but dosing is challenging because of its narrow therapeutic window and pharmacokinetic (PK) variability. Popul
Externí odkaz:
https://doaj.org/article/90ef046582c94502abeab347f50b51a1
Autor:
Anjali Majumdar, Mansi R. Shah, Jiyeon J. Park, Navaneeth Narayanan, Keith S. Kaye, Pinki J. Bhatt
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 592 (2023)
Antimicrobial stewardship programs play a critical role in optimizing the use of antimicrobials against pathogens in the era of growing multi-drug resistance. However, implementation of antimicrobial stewardship programs among the hematopoietic stem
Externí odkaz:
https://doaj.org/article/1c2cbaa9dcc64068821cedfa8a66d9c5
Autor:
Merlin Moni, A Sangita Sudhir, T.S. Dipu, Zubair Mohamed, Binny Pushpa Prabhu, Fabia Edathadathil, Sabarish Balachandran, Sanjeev K Singh, Preetha Prasanna, Veena P Menon, Twisha Patel, Payal Patel, Keith S Kaye, Vidya P Menon
Publikováno v:
International Journal of Infectious Diseases, Vol 100, Iss , Pp 497-506 (2020)
Background: Safe and effective use of colistin requires robust pharmacokinetic (PK) and pharmacodynamic (PD) data to guide dosing. Aim: To evaluate the pharmacokinetics of colistimethate sodium and colistin in critically ill patients and correlate wi
Externí odkaz:
https://doaj.org/article/d762c59f37134de5938248544a95a990