Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Keith Raymond Mulholland"'
Autor:
Peter Ham, J V Selkirk, Frank E. Blaney, Susannah Davies, L M Gaster, David Malcolm Duckworth, John M. Hatcher, Derek N. Middlemiss, Gary W. Price, Frank King, P. D. Slade, Jim J. Hagan, Wyman Paul Adrian, Graham Francis Joiner, Claire Roberts, Sarah Margaret Jenkins, Carol Routledge, Keith Raymond Mulholland, Riley Gj, Andrew John Jennings, B. J. Jones
Publikováno v:
Journal of Medicinal Chemistry. 41:1218-1235
5-HT1 receptors are members of the G-protein-coupled receptor superfamily and are negatively linked to adenylyl cyclase activity. The human 5-HT1B and 5-HT1D receptors (previously known as 5-HT1Dbeta and 5-HT1Dalpha, respectively), although encoded b
Autor:
Keith Raymond Mulholland, E.S. Ellis, S Starr, Andrew John Jennings, Wyman Paul Adrian, L M Gaster, Frank King, Graham Francis Joiner, Kay A. Wardle, Sh K Rahman
Publikováno v:
Journal of Medicinal Chemistry. 36:4121-4123
Autor:
Stephen E. Clarke, G. E. Jones, Steven Mark Bromidge, David T. Davies, Wyman Paul Adrian, Peter Ham, Sean Lightowler, Derek N. Middlemiss, Saunders Dv, Brenda K. Trail, Holland, Keith Raymond Mulholland, Ian Thomson Forbes, Frank E. Blaney, Riley Gj, Thomas P. Blackburn, David Malcolm Duckworth, Guy A. Kennett, Steven Dabbs, Susannah Davies, L M Gaster, Frank King, Wood
Publikováno v:
Journal of medicinal chemistry. 43(6)
The evolution, synthesis, and biological activity of a novel series of 5-HT(2C) receptor inverse agonists are reported. Biarylcarbamoylindolines have been identified with excellent 5-HT(2C) affinity and selectivity over 5-HT(2A) receptors. In additio