Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Keith R.F. Elliott"'
Autor:
Keith R.F. Elliott
Publikováno v:
Turkish Journal of Biochemistry. 43:17-17
Publikováno v:
European Journal of Biochemistry. 259:684-691
The primary aim of this paper was to calculate and report flux control coefficients for mitochondrial outer-membrane carnitine palmitoyltransferase (CPT I) over hepatic ketogenesis because its role in controlling this pathway during the neonatal peri
Autor:
T. M. Pocock, J. P. Chapat, Karine Portet, Guy Subra, Pierre-Antoine Bonnet, Alain Michel, Veronique Benezech, Olivier Vitse, Lahcen Zanik, Roger C. Small, F. Laurent, Keith R.F. Elliott, J. Bompart
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:1059-1065
New imidazo[1,2-a]pyrazine derivatives have been synthesized either by direct cyclization from pyrazines or by electrophilic substitutions. The presence of electron donating groups on position 8 greatly enhances the reactivity of the heterocycle towa
Autor:
K. K. Patil, Simon Eaton, Karen J. New, Patti A. Quant, Keith R.F. Elliott, N. Azzouzi, C. V. Lascelles
Publikováno v:
Biochemical Society Transactions. 26:125-130
Autor:
John R. Fozard, Roger C. Small, K. Archer, Andrew J. Miller, A. Martin, K.H. Buchheit, Keith R.F. Elliott, S.J. Cook, T. Müller, R.W. Foster
Publikováno v:
British Journal of Pharmacology. 114:143-151
1. SCA40 (1nM-10 microM), isoprenaline (1-300 nM) and levcromakalim (100 nM-10 microM) each produced concentration-dependent suppression of the spontaneous tone of guinea-pig isolated trachea. Propranolol (1 microM) markedly (approximately 150 fold)
Autor:
Jacqueline L. Berry, Ian D. Chapman, Keith R.F. Elliott, Roger C. Small, R.W. Foster, Andrew J. Watt, John P. Boyle
Publikováno v:
European Journal of Pharmacology. 192:417-426
In Triton X-100-skinned trachealis muscle, neither papaverine nor AH 21-132 modified responses to Ca 2+ . The (−)-enantiomer of AH 21-132 was more potent than the (+)-enantiomer both in relaxing intact trachealis muscle and in inhibiting tracheal c
Publikováno v:
Journal of Enzyme Inhibition. 4:245-251
The smooth muscle relaxant, AH 21-132, was tested for its inhibitory effect on the cyclic nucleotide phosphodiesterase (PDE) activities fractionated from guinea-pig cardiac ventricle and bovine trachealis muscle. Both tissues yielded significant PDE-
Autor:
F. Laurent, J. P. Chapat, Roger C. Small, Keith R.F. Elliott, Pierre-Antoine Bonnet, Carine Deleuze-Masquéfa, Roger Escale, Jean Roch Fabreguettes, Jean Vidal, Stéphanie Parra, Guy Subra, T. M. Pocock, Alain Michel, Veronique Benezech
Publikováno v:
European journal of medicinal chemistry. 36(3)
A group of imidazo[1,2-a]quinoxalines have been synthesised from quinoxaline by condensation of an appropriate haloester or intramolecular cyclisation of a keto moiety on an intracyclic nitrogen atom. The reactivity of the heterocycle was explored th
Autor:
F. Laurent, R.W. Foster, Keith R.F. Elliott, Roger C. Small, Peter Chiu, Alain Michel, Pierre-Antoine Bonnet, T. M. Pocock, Lynne M. Isaac
Publikováno v:
European journal of pharmacology. 334(1)
While UK-93,928 (1-[[3-(6,9-dihydro-6-oxo-9-propyl-1H-purin-2-yl)-4-ethoxyphenyl] sulfonyl]-4-methylpiperazine; 5 nM–5 μ M) was devoid of relaxant activity, benzafentrine, isoprenaline, levcromakalim and SCA40 (6-bromo-8-methylaminoimidazo[1,2- a
Publikováno v:
Biochemical Society transactions. 23(2)