Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Keith R. Hudson"'
Autor:
Bridget Dicker, Keith R. Hudson, Jiwon Hong, Shakeela N Jayasinghe, Dug Yeo Han, Francesca De Gregorio, Hong Tian
Publikováno v:
Biology of reproduction. 97(5)
The vast majority of sperm are lost from the female reproductive tract in hours following natural mating or artificial insemination in mammals. Multiple complex processes including uterine contractions, mucus barriers, and phagocytosis of sperm by ne
Autor:
Brian D. Quinn, Natalie E. Netzler, Humphrey C.C. Foote, Anne-Marie Smit, Philip J. O'Donnell, Niels J. Nieuwenhuizen, Timothy J. Strabala, Keith R. Hudson, E. Jane Martin, Charles Ampomah-Dwamena
Publikováno v:
Plant Physiology. 140:1331-1344
Secreted peptide ligands are known to play key roles in the regulation of plant growth, development, and environmental responses. However, phenotypes for surprisingly few such genes have been identified via loss-of-function mutant screens. To begin t
Publikováno v:
Journal of Biological Chemistry. 275:36197-36203
Interleukin-11 (IL-11) is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor gp130. IL-11 has been shown
Publikováno v:
Cell Adhesion and Communication. 7:465-476
The Rac1 small GTP-binding protein is known to be involved in reorganization of the actin cytoskeleton and in regulation of intracellular signal transduction. The assembly and maintenance of cadherin-based cell cell junctions in epidermal keratinocyt
Publikováno v:
Journal of Biological Chemistry. 272:26947-26952
The leukemia inhibitory factor receptor (LIF-R) is activated not only by LIF, but also by cardiotrophin-1, ciliary neurotrophic factor with its receptor, and oncostatin M (OSM). Each of these cytokines induces the hetero-oligomerization of LIF-R with
Autor:
Achim Gossler, Julia Karow, Keith R. Hudson, John K. Heath, Mark A. Hall, Jacky A. Taylor, Ann B. Vernallis
Publikováno v:
Biochemical Journal. 318:489-495
Interleukin-11 (IL-11) is a polyfunctional cytokine whose biological actions require a specific IL-11 receptor (IL-11R) and the transmembrane transducer gp130. Here we report the production of a soluble form of the murine IL-11R and demonstrate that
Publikováno v:
The Journal of Experimental Medicine
The superantigen staphylococcal enterotoxin A (SEA) binds to major histocompatibility complex (MHC) class II molecules at two sites on either side of the peptide groove. Two separate but cooperative interactions to the human class II molecule HLA-DR1
Autor:
Nicholas R. J. Gascoigne, Michael J. Irwin, John D. Fraser, Kristina T. Ames, Keith R. Hudson
Publikováno v:
Immunological Reviews. 131:61-78
The last few years have seen an enormous jump in our knowledge and understanding of T-cell activation by superantigens. Clearly, a great number of infectious and parasitic organisms utilize superantigens as part of a strategy to evade the immune resp
Publikováno v:
Nature. 359:841-843
Superantigens such as the staphylococcal enterotoxins bind to major histocompatibility complex (MHC) class II molecules and activate T cells through a specific interaction between the V beta region of the T-cell antigen receptor (TCR) and the toxin.
Publikováno v:
The Journal of biological chemistry. 274(9)
Interleukin-11 (IL-11) is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor gp130. A complex of IL-11 a