Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Keith R McCrae"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Thromboembolism (TE) in cancer significantly contributes to morbidity and mortality. Little is known about the incidence of arterial TE (ATE) and venous TE (VTE) in patients with melanoma on immune checkpoint inhibitor (ICI) therapy.Method
Externí odkaz:
https://doaj.org/article/014869f0ef944a95a200ff581bc1fc3e
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e94048 (2014)
The association between malignancy and venous thromboembolic disease (VTE) is well established. The independent impact of VTE, both symptomatic and incidental, on survival in patients with prostate cancer is not known. We conducted a retrospective co
Externí odkaz:
https://doaj.org/article/ec0943e56728428b8da72288fa899680
Autor:
Sharmeen Sorathia, Aro Daniela Arockiam, Elio Haroun, Rishabh Khurana, Alexandra Hall, Meghann McCarthy, Rupal K. Shastri, Hanny Sawaf, Keith R. McCrae, Christine L. Jellis, Tom Kai Ming Wang
Publikováno v:
Clinical Case Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Key Clinical Message Our case depicts a challenging diagnosis of catastrophic antiphospholipid syndrome in a young patient with a heterogenous presentation with extensive clinical course, a wide range of investigations, including multimodality imagin
Externí odkaz:
https://doaj.org/article/1ac10fbe77df44fd9c8c15c26d406529
Autor:
Lorenzo Cirasino, Anna M. Robino, GianMarco Podda, Emmanuel Andrès, Jenny M. Despotovic, Mohsen Elalfy, Andreas Holbro, Tadakazu Kondo, Michele P. Lambert, Sandra R. Loggetto, Keith R. McCrae, Jong Wook Lee, Marco Cattaneo
Publikováno v:
Platelets, Vol 31, Iss 4, Pp 461-473 (2020)
Despite the publication in 2009 of a paper on ‘terms and definitions of immune thrombocytopenia’ (ITP), some unresolved issues remain and are reflected by the disagreement in the treatment suggested for primary ITP in adults. Considering that the
Externí odkaz:
https://doaj.org/article/1bd77229c7c94490991edc2b5b051083
Autor:
Cindy Neunert, Deirdra R. Terrell, Donald M. Arnold, George Buchanan, Douglas B. Cines, Nichola Cooper, Adam Cuker, Jenny M. Despotovic, James N. George, Rachael F. Grace, Thomas Kühne, David J. Kuter, Wendy Lim, Keith R. McCrae, Barbara Pruitt, Hayley Shimanek, Sara K. Vesely
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 3829-3866 (2019)
Abstract: Background: Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist physicians with the management of patients.Objective: These e
Externí odkaz:
https://doaj.org/article/61b0918c8aaf4076a09ba65bc53595e5
Autor:
Zu-Lin Chen, Pradeep K. Singh, Katharina Horn, Marissa R. Calvano, Shigeru Kaneki, Keith R. McCrae, Sidney Strickland, Erin H. Norris
Publikováno v:
Blood Advances. 7:1156-1167
A dysregulated plasma contact system is involved in various pathological conditions, such as hereditary angioedema, Alzheimer disease, and sepsis. We previously showed that the 3E8 anti–high molecular weight kininogen (anti-HK) antibody blocks HK c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec367307bc731f50c40b58f351407f54
https://doi.org/10.1182/bloodadvances.2021006485
https://doi.org/10.1182/bloodadvances.2021006485
Autor:
Shruti, Chaturvedi, Ana G, Antun, Andrew M, Farland, Ryan, Woods, Ara, Metjian, Yara A, Park, Gustaaf, de Ridder, Briana, Gibson, Raj S, Kasthuri, Darla K, Liles, Frank, Akwaa, Todd, Clover, Lisa, Baumann Kreuziger, J Evan, Sadler, Meera, Sridharan, Ronald S, Go, Keith R, McCrae, Harsh Vardhan, Upreti, Angela, Liu, Ming Y, Lim, Radhika, Gangaraju, X Long, Zheng, Jay S, Raval, Camila, Masias, Spero R, Cataland, Andrew, Johnson, Elizabeth, Davis, Michael D, Evans, Marshall A, Mazepa
Publikováno v:
Blood. 140:1335-1344
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ impairment. Black patients are overrepresented in iTTP cohorts in the United States, but racial di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc4cc94bbaac641f87df27b51dd51a7
https://doi.org/10.1182/blood.2022016640
https://doi.org/10.1182/blood.2022016640
Autor:
Raj S. Kasthuri, Shruti Chaturvedi, Sonia Thomas, Nathan Vandergrift, Carla Bann, Nicole Schaefer, Marianne S. Clancy, Reed Pyeritz, Keith R. McCrae
Publikováno v:
Blood Advances. 6:4301-4309
Hereditary hemorrhagic telangiectasia (HHT) is characterized by arteriovenous malformations and telangiectasia, with primary clinical manifestations of epistaxis and gastrointestinal bleeding and resultant anemia. HHT negatively affects health-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7b010516c52e3bdc8f29d0ec8df08c
https://doi.org/10.1182/bloodadvances.2022007748
https://doi.org/10.1182/bloodadvances.2022007748
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The antiphospholipid syndrome (APS) is characterized by thrombosis and pregnancy morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of enzymes and regulatory proteins of the innate immune system that plays a key ro
Externí odkaz:
https://doaj.org/article/14023e661740444fa7dfcf59969066f3
Autor:
Jonathan C. Roberts, Keith R. McCrae, Habiba Hussain, Michael D. Tarantino, Shruti Chaturvedi
Publikováno v:
Blood Advances. 6:1271-1277
Introduction:Antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis in the presence of antiphospholipid antibodies. Recently, derangement in the complement pathway has been implicated in APS pathophysiology. Refractory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb15be2bf1e3b1d82b18a77bb2155967
https://doi.org/10.1182/bloodadvances.2021005657
https://doi.org/10.1182/bloodadvances.2021005657