Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Keith Q Wu"'
Autor:
Syed IA Bukhari, Samuel S Truesdell, Chandreyee Datta, Pritha Choudhury, Keith Q Wu, Jitendra Shrestha, Ruby Maharjan, Ethan Plotsker, Ramzi Elased, Sadia Laisa, Vijeta Bhambhani, Yue Lin, Johannes Kreuzer, Robert Morris, Siang-Boon Koh, Leif W. Ellisen, Wilhelm Haas, Amy Ly, Shobha Vasudevan
Publikováno v:
bioRxiv
Our data previously revealed that chemosurviving cancer cells translate specific genes. Here, we find that the m6A-RNA-methyltransferase, METTL3, increases transiently in chemotherapy-treated breast cancer and leukemic cells in vitro and in vivo. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c648e406c889874ee2a350109453e95
https://doi.org/10.1101/2023.05.19.540602
https://doi.org/10.1101/2023.05.19.540602
Autor:
Olin D Liang, Eui Young So, Keith Q. Wu, Anthony M. Reginato, Patrycja M. Dubielecka, Changqi Sun
Publikováno v:
Am J Physiol Cell Physiol
Rheumatoid arthritis (RA) is a debilitating autoimmune disease of unknown cause, characterized by infiltration and accumulation of activated immune cells in the synovial joints where cartilage and bone destructions occur. Myeloid-derived suppressor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110f41dfe25accf773c61fe4b924b5bf
https://doi.org/10.1152/ajpcell.00433.2020
https://doi.org/10.1152/ajpcell.00433.2020
Autor:
Chandreyee Datta, Samuel S. Truesdell, Keith Q. Wu, Syed I. A. Bukhari, Harrison Ngue, Brienna Buchanan, Olivier Le Tonqueze, Sooncheol Lee, Swapna Kollu, Madeleine A. Granovetter, Myriam Boukhali, Johannes Kreuzer, Maheen S. Batool, Leonora Balaj, Wilhelm Haas, Shobha Vasudevan
Publikováno v:
Science Advances. 8
Quiescent leukemic cells survive chemotherapy, with translation changes. Our data reveal that FXR1, a protein amplified in several aggressive cancers, is elevated in quiescent and chemo-treated leukemic cells and promotes chemosurvival. This suggests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40584a391f5eb87fe97400e4dd9c82e
https://doi.org/10.1126/sciadv.abo1304
https://doi.org/10.1126/sciadv.abo1304
Autor:
Anthony M. Reginato, Patrycja M. Dubielecka, Euy-Myoung Jeong, Eui Young So, Keith Q. Wu, Peter J. Quesenberry, Olin D Liang
Publikováno v:
Aging (Albany NY)
Adult hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) ensuring homeostasis of blood production and immune response throughout life. Sex differences in immunocompetence and mortality are well-documented in humans. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86a3d42743e7f20ba827ddb152f7b22
https://doi.org/10.18632/aging.202167
https://doi.org/10.18632/aging.202167
Autor:
James R. Klinger, Corey E. Ventetuolo, Alexander S. Brodsky, Jason M. Aliotta, Mandy Pereira, Mark S. Dooner, Sicheng Wen, Keith Q. Wu, Laura R. Goldberg, Michael Del Tatto, Peter J. Quesenberry, Theodore Borgovan, Olin D Liang
Publikováno v:
Am J Respir Cell Mol Biol
Mesenchymal stem cell extracellular vesicles attenuate pulmonary hypertension, but their ability to reverse established disease in larger animal models and the duration and mechanism(s) of their effect are unknown. We sought to determine the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332548fb771d8d8cd09dcf67b431ebfe
https://doi.org/10.1165/rcmb.2019-0154oc
https://doi.org/10.1165/rcmb.2019-0154oc
Autor:
C. Datta, SS. Truesdell, SIA. Bukhari, H. Ngue, B. Buchanan, Keith Q. Wu, O. Le Tonqueze, S. Lee, M. Granovetter, M. Boukhali, J. Kreuzer, W. Haas, S. Vasudevan
Quiescent leukemic cells survive chemotherapy, with translation changes. Our data reveal that FXR1, a protein amplified in several aggressive cancers, increases in quiescent and chemo- treated leukemic cells, and promotes chemosurvival. This suggests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec066d11ab7fd4c3f4b8d18b86bd449
https://doi.org/10.1101/2021.12.07.471635
https://doi.org/10.1101/2021.12.07.471635
Autor:
Anthony M. Reginato, Adam Driesman, Eui Young So, Olin D Liang, Changqi Sun, Travis Spangler, Mauricio Isaac, Susan E. Leggett, Keith Q. Wu, Patrycja M. Dubielecka‐Szczerba
Publikováno v:
Journal of Cellular Physiology
SH2‐containing inositol‐5′‐phosphatase‐1 (SHIP‐1) controls the phosphatidylinositol‐3′‐kinase (PI3K) initiated signaling pathway by limiting cell membrane recruitment and activation of Akt. Despite the fact that many of the growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13983bc895117005ee06edb648f81769
https://doi.org/10.1002/jcp.29063
https://doi.org/10.1002/jcp.29063
Autor:
Euy-Myoung Jeong, Mandy Pereira, Eui-Young So, Keith Q Wu, Michael Del Tatto, Sicheng Wen, Mark S Dooner, Patrycja M Dubielecka, Anthony M Reginato, Corey E Ventetuolo, Peter J Quesenberry, James R Klinger, Olin D Liang
Publikováno v:
Cardiovascular research. 118(16)
Aims Pulmonary arterial hypertension (PAH) is a fatal disease without a cure. Previously, we found that transcription factor RUNX1-dependent haematopoietic transformation of endothelial progenitor cells may contribute to the pathogenesis of PAH. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f5430d4dae401e4997b45d1880e5d0
https://pubmed.ncbi.nlm.nih.gov/35018410
https://pubmed.ncbi.nlm.nih.gov/35018410
Autor:
M. Del Tatto, James R. Klinger, Keith Q. Wu, Peter J. Quesenberry, Olin D Liang, Eui Young So, Mark S. Dooner, E.-M. Jeong, Mandy Pereira, Corey E. Ventetuolo
Publikováno v:
A107. BYSTANDERS NO MORE: INFLAMMATION, IMMUNITY AND THROMBOSIS IN PULMONARY VASCULAR AND LUNG DISEASE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83a25f17b915c71d8028a75a033e623
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2673
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2673
M1 Macrophage–Induced Endothelial-to-Mesenchymal Transition Promotes Infantile Hemangioma Regression
Autor:
Keith Q. Wu, Christopher S. Muratore, Olin D Liang, Eui Young So, Patrycja M. Dubielecka, Changqi Sun, Anthony M. Reginato
Publikováno v:
The American Journal of Pathology. 187:2102-2111
Infantile hemangiomas are benign tumors of vascular endothelial cells (ECs), characterized by three distinct stages: proliferating phase, involuting phase, and involuted phase. The mechanisms that trigger involution of hemangioma into fibro-fatty tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b6c3385f68fdd5c54c0bdd4924f473
https://doi.org/10.1016/j.ajpath.2017.05.014
https://doi.org/10.1016/j.ajpath.2017.05.014