Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Keith M. Thompson"'
Autor:
Audun Os, Simone Bürgler, Anna Parente Ribes, Ane Funderud, Dong Wang, Keith M. Thompson, Geir E. Tjønnfjord, Bjarne Bogen, Ludvig A. Munthe
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 566-577 (2013)
There is increasing interest in the chronic lymphocytic leukemia (CLL) microenvironment and the mechanisms that may promote CLL cell survival and proliferation. A role for T helper (Th) cells has been suggested, but current evidence is only circumsta
Externí odkaz:
https://doaj.org/article/e93e963acec147dbbab6bb8c9617a273
Autor:
Ingrid Randen, Kirsten Sørensen, Reidun Hauge, Anine B. Dahlberg, Mohammad R. Mirlashari, Keith M. Thompson, Jens Kjeldsen-Kragh
Publikováno v:
Haematologica, Vol 93, Iss 4 (2008)
Alloimmunization is a common phenomenon after transfusion, with an estimated incidence of 0.5% increasing to 20–60% in chronically transfused patients. In recently transfused patients, serological typing can be hampered by mixed field agglutination
Externí odkaz:
https://doaj.org/article/66e54f8bac524277a58e471c5256e973
Autor:
Marianne Frøyland, Keith M. Thompson, Susan J. Thorpe, Surinder S. Sahota, Tobias Gedde-Dahl, Bjarne Bogen
Publikováno v:
Haematologica, Vol 92, Iss 5 (2007)
It has been suggested that VH4-34 gene segment expression is counter-selected in multiple myeloma (MM) due to a self-tolerance mechanism. We cloned and sequenced a VH4-34 gene segment from bone marrow mononuclear cells of a stage III MM patient. We s
Externí odkaz:
https://doaj.org/article/b8a89d9ac7534698bf128d49006780f1
Publikováno v:
The Journal of Immunology. 193:2691-2698
Systemic lupus erythematosus (SLE) is marked by a Th cell–dependent B cell hyperresponsiveness, with frequent germinal center reactions and hypergammaglobulinemia. The specificity of Th cells in lupus remains unclear, but B cell Ids have been sugge
Autor:
Geir E. Tjønnfjord, Keith M. Thompson, Audun Os, Simone Bürgler, Anna Parente Ribes, Ludvig A. Munthe, Ane Funderud, Bjarne Bogen, Dong Wang
Publikováno v:
Cell reports
Cell Reports, Vol 4, Iss 3, Pp 566-577 (2013)
Cell Reports, Vol 4, Iss 3, Pp 566-577 (2013)
SummaryThere is increasing interest in the chronic lymphocytic leukemia (CLL) microenvironment and the mechanisms that may promote CLL cell survival and proliferation. A role for T helper (Th) cells has been suggested, but current evidence is only ci
Autor:
Boris Tichy, Agnieszka Janus, Lone Bredo Pedersen, Xavier Brochet, Nikos Darzentas, C. Belessi, M. Ponzoni, Frederic Davi, J. Jurlander, Paolo Ghia, Kostas Stamatopoulos, Achilles Anagnostopoulos, Maria Gounari, P. F. Di Celle, Véronique Giudicelli, Šárka Pospíšilová, Efterpi Kostareli, David Oscier, Anastasia Kouvatsi, Keith M. Thompson, Richard Rosenquist, Letizia Foroni, Marie-Paule Lefranc, Fiona Murray
Publikováno v:
Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2012, 26 (5), pp.1127-1131. ⟨10.1038/leu.2011.311⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2012, 26 (5), pp.1127-1131. ⟨10.1038/leu.2011.311⟩
Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity
Publikováno v:
The Journal of Immunology. 187:2867-2874
To understand the biology of Ab-secreting cells in the human small intestine, we examined Ab production of intestinal biopsies kept in culture. We found sustained IgA and IgM secretion as well as viable IgA- or IgM-secreting cells after >4 wk of cult
Autor:
Pier Adelchi Ruffini, Bjarne Bogen, Agnete Brunsvik Fredriksen, Tobias Gedde-Dahl, Keith M. Thompson, Marianne Frøyland
Publikováno v:
European Journal of Haematology. 86:385-395
Objectives: A homodimeric fusion DNA vaccine targeting idiotype (Id) to antigen-presenting cells (APC) induced robust tumor protection in a mouse model of multiple myeloma (MM). Similar Id vaccine molecules were generated for four patients with MM wi
Publikováno v:
Annals of the New York Academy of Sciences. 764:440-449
We have compared RF from normal, immunized donors and RF derived from the synovial tissues of RA patients. We have found a difference in the preferential use of VL and VH gene families. In both conditions, RFs were found to have accumulated somatic m
Autor:
Susan J. Thorpe, Christine Ball, Keith M. Thompson, Bernard Fox, Adrian Bristow, Robin Thorpe
Publikováno v:
Transfusion. 48:930-940
BACKGROUND: The heavy-chain V 4-34 germline gene segment is mandatory for pathologic cold-reacting autoantibodies with anti-j/i specificity (cold agglutinins) and is also preferentially used by monoclonal immunoglobulin M alloantibodies against D and