Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Keith M. Porter"'
Autor:
Jessica M. Boname, Clemens Hermann, Keith M. Porter, Paul J. Lehner, John Trowsdale, Marian L. Burr, Karsten Skjødt, Michael E. Harbour, Peysh A. Patel, Louise H. Boyle, David Rhodes, Lidia M. Duncan
Publikováno v:
Boyle, L H, Hermann, C, Boname, J M, Porter, K M, Patel, P A, Burr, M L, Duncan, L M, Harbour, M E, Rhodes, D A, Skjødt, K, Lehner, P J & Trowsdale, J 2013, ' Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 9, pp. 3465-3470 . https://doi.org/10.1073/pnas.1222342110
Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, I
Autor:
Isabel, Huang-Doran, Louise S, Bicknell, Francis M, Finucane, Nuno, Rocha, Keith M, Porter, Y C Loraine, Tung, Ferenc, Szekeres, Anna, Krook, John J, Nolan, Mark, O'Driscoll, Michael, Bober, Stephen, O'Rahilly, Andrew P, Jackson, Robert K, Semple, Natalia, Volevodz
Publikováno v:
Huang-Doran, I, Bicknell, L S, Finucane, F M, Rocha, N, Porter, K M, Tung, Y C L, Szekeres, F, Krook, A, Nolan, J J, O'Driscoll, M, Bober, M, O'Rahilly, S & Jackson, A P & Semple, R K 2011, ' Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes ', Diabetes, vol. 60, no. 3, pp. 925-935 . https://doi.org/10.2337/db10-1334
Diabetes
Diabetes
OBJECTIVE Genetic defects in human pericentrin (PCNT), encoding the centrosomal protein pericentrin, cause a form of osteodysplastic primordial dwarfism that is sometimes reported to be associated with diabetes. We thus set out to determine the preva
Autor:
Inês Barroso, Victoria E. R. Parker, J. Kirk, Keith M. Porter, Christian J. Hendriksz, Robert K. Semple, Stephen O'Rahilly
Publikováno v:
Journal of Inherited Metabolic Disease
In Npc1 null mice, a model for Niemann Pick Disease Type C1, it has been reported that hepatocyte insulin receptor function is significantly impaired, consistent with growing evidence that membrane fluidity and microdomain structure have an important
Autor:
Keith M, Porter
Publikováno v:
Emergency Medicine Journal. 27:940-942
Prehospital surgical amputations are rarely necessary. This paper gives a historical perspective, the indications and contraindications for limb amputations, and details a simple technique for both surgeons and non-surgically qualified medical person
Publikováno v:
Immunology
The tapasin-related protein TAPBPR is a novel component of the antigen processing and presentation pathway, which binds to MHC class I coupled with β2-microglobulin. We describe six alternatively spliced TAPBPR transcripts from the TAPBPL gene and i
Autor:
Fiona M. Gribble, Serap Turan, Frank Reimann, Gwen Tolhurst, Stephen O'Rahilly, Zeynep Atay, Tulay Guran, Robert K. Semple, A. Kemal Topaloglu, L. Damla Kotan, Teoman Akcay, Nuno Rocha, Ayşe Serin, Abdullah Bereket, Husniye Canan, Keith M. Porter
Publikováno v:
The Journal of clinical endocrinology and metabolism. 94(10)
PubMedID: 19755480 Context: The neurokinin B (NKB) receptor, encoded by TACR3, is widely expressed within the central nervous system, including hypothalamic nuclei involved in regulating GnRH release. We have recently reported two mutations in transm
Autor:
Metin Guclu, Ayse Serap Yalin, Sazi Imamoglu, Ayşe Serin, Joshua R. Cook, Mehmet Nuri Ozbek, Neslihan Önenli Mungan, N Sema Akalin, Bilgin Yüksel, Stephen O'Rahilly, Keith M. Porter, L. Damla Kotan, Robert K. Semple, Frank Reimann, A. Kemal Topaloglu
PubMedID: 19079066 The timely secretion of gonadal sex steroids is essential for the initiation of puberty, the postpubertal maintenance of secondary sexual characteristics and the normal perinatal development of male external genitalia. Normal gonad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb1155b5a4162caae74bf5a3874ca87
https://europepmc.org/articles/PMC4312696/
https://europepmc.org/articles/PMC4312696/
Autor:
Caroline, Lee, Keith M, Porter
Publikováno v:
Emergency Medicine Journal. 24:237-238
Suspension trauma (also known as "harness-induced pathology" or "orthostatic shock while suspended") is the development of presyncopal symptoms and loss of consciousness if the human body is held motionless in a vertical position for a period of time
Autor:
David A. Rhodes, Peysh A. Patel, Louise H. Boyle, Jessica M. Boname, Paul J. Lehner, Marian L. Burr, Keith M. Porter, John Trowsdale
Publikováno v:
Molecular Immunology. 51:10
Autor:
Keith M Porter, Michael J. Turner
Publikováno v:
BMJ. 335:s94.2-s94
We are writing in response to the article “Doc at the races,” which appears to suggest that no training or experience is necessary to work in racing as a medic.1 There are …