Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Keith M. Erikson"'
Autor:
Keith M. Erikson, Kristina El-Khouri, Radmila Petric, Chenhao Tang, Jinlan Chen, Delicia Esther Cardenas Vasquez, Steve C. Fordahl, Zhenquan Jia
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1081 (2023)
Abnormal cholesterol metabolism can lead to oxidative stress in the brain. Low-density lipoprotein receptor (LDLr) knockout mice are models for studying altered cholesterol metabolism and oxidative stress onset in the brain. Carbon nanodots are a new
Externí odkaz:
https://doaj.org/article/9322e11882604c4585ba650b964d9d27
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13778 (2022)
The objective of this study was to determine the influence of sex and strain on the dysregulation of trace element concentration and associative gene expression due to diet induced obesity in adipose tissue and the liver. Male and female C57BL/6J (B6
Externí odkaz:
https://doaj.org/article/ddbe8ab7ae7048bfbb9d56a5290a80e8
Publikováno v:
Nutrients, Vol 12, Iss 12, p 3909 (2020)
The aim of this study was to determine the impact of diet-induced obesity (DIO) on trace element homeostasis and gene expression in the olfactory bulb and to identify potential interaction effects between diet, sex, and strain. Our study is based on
Externí odkaz:
https://doaj.org/article/735e7e706fab49079fa8c56232275015
Autor:
Asad A. Aboud, Andrew M. Tidball, Kevin K. Kumar, M. Diana Neely, Bingying Han, Kevin C. Ess, Charles C. Hong, Keith M. Erikson, Peter Hedera, Aaron B. Bowman
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 204-212 (2015)
Poorly-defined interactions between environmental and genetic risk factors underlie Parkinson's disease (PD) etiology. Here we tested the hypothesis that human stem cell derived forebrain neuroprogenitors from patients with known familial risk for ea
Externí odkaz:
https://doaj.org/article/a50689e8e4a94a1bbc251e240c2de139
Autor:
Charles V. Vorhees, Devon L. Graham, Robyn M. Amos-Kroohs, Amanda A. Braun, Curtis E. Grace, Tori L. Schaefer, Matthew R. Skelton, Keith M. Erikson, Michael Aschner, Michael T. Williams
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 1046-1061 (2014)
Developmental exposure to manganese (Mn) or stress can each be detrimental to brain development. Here, Sprague-Dawley rats were exposed to two housing conditions and Mn from postnatal day (P)4–28. Within each litter two males and two females were a
Externí odkaz:
https://doaj.org/article/3c02fa89f84842238e86c4577e7f95bd
Publikováno v:
Nutritional Neuroscience. 25:2601-2615
BACKGROUND Obesity has been linked to behavioral and biochemical changes, such as reduced physical activity, dysregulated dopamine metabolism, and gene expression alterations in the brain. The impact of a continuous high-fat diet and resulting state
Autor:
Robert W. Williams, Keith M. Erikson, Carolina Torres-Rojas, Megan K. Mulligan, Wenyuan Zhao, Lu Lu, Daming Zhuang, Byron C. Jones
Publikováno v:
Biometals
One common characteristic of neurodegenerative diseases is dysregulation of iron, usually with observed increases in its concentration in various regions. Heavy alcohol consumption is believed to contribute to such iron dysregulation in the brain wit
Autor:
Aaron B. Bowman, Keith M. Erikson, Daniel O. Claassen, Hakmook Kang, Yan Yan, Melissa Totten, James Silverman, Anna C Pfalzer
Publikováno v:
Scientific Reports. 12
Objective: The importance of metal biology in neurodegenerative diseases such as Huntingtin Disease is well documented with evidence of direct interactions between metals such as copper, zinc, iron and manganese and mutant Huntingtin pathobiology. To
Autor:
Keith M. Erikson, Jordyn M. Wilcox, Stacy D. Sherrod, Fiona E. Harrison, Preethi Umashanker, Aaron B. Bowman, Timothy Halbesma, Nancy L. Parmalee, Kevin L Yang, Anna C Pfalzer, Terry Jo Bichell, Melissa Totten, John A. McLean, Michael Aschner, Simona G. Codreanu
Publikováno v:
Metallomics
Manganese (Mn) is an essential micronutrient required for the proper function of several enzymes. Accumulating evidence demonstrates a selective decrease of bioavailable Mn in vulnerable cell types of Huntington’s Disease (HD), an inherited progres
Autor:
Keith M. Erikson, Aaron B. Bowman, Adriana A. Tienda, Anna C Pfalzer, Jordyn M. Wilcox, Ellen C. Cox, Fiona E. Harrison, Melissa Totten, Ines F. Debbiche
Publikováno v:
Neurotoxicology
Manganese (Mn) is an essential micronutrient but excessive levels induce neurotoxic effects. Increasing evidence suggests a deficit of bioavailable Mn in Huntington disease (HD), an inherited neurodegenerative disease characterized by motor and cogni