Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Keith M Erikson"'
Publikováno v:
Frontiers in Nutrition, Vol 3 (2016)
Adequate brain iron levels are essential for enzyme activities, myelination, and neurotransmitter synthesis in the brain. Although systemic iron deficiency has been found in genetically or dietary-induced obese subjects, the effects of obesity-associ
Externí odkaz:
https://doaj.org/article/79a8f9fdd3ff4d97a61c39d0ac8a854c
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3301 (2024)
Objective: The objective of this study was to determine the influence of sex and strain on striatal and nucleus accumbens dopamine neurochemistry and dopamine-related behavior due to a high-saturated-fat diet (HFD). Methods: Male and female C57B6/J (
Externí odkaz:
https://doaj.org/article/a453882cf79c4a3bac927e44686102de
Autor:
Fabiano M Cordova, Aderbal S Aguiar, Tanara V Peres, Mark W Lopes, Filipe M Gonçalves, Aline P Remor, Samantha C Lopes, Célso Pilati, Alexandra S Latini, Rui D S Prediger, Keith M Erikson, Michael Aschner, Rodrigo B Leal
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33057 (2012)
Manganese (Mn) is an essential metal for development and metabolism. However, exposures to high Mn levels may be toxic, especially to the central nervous system (CNS). Neurotoxicity is commonly due to occupational or environmental exposures leading t
Externí odkaz:
https://doaj.org/article/f16e7b7814864728b045cbe9c9aab524
Autor:
Keith M. Erikson, Kristina El-Khouri, Radmila Petric, Chenhao Tang, Jinlan Chen, Delicia Esther Cardenas Vasquez, Steve C. Fordahl, Zhenquan Jia
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1081 (2023)
Abnormal cholesterol metabolism can lead to oxidative stress in the brain. Low-density lipoprotein receptor (LDLr) knockout mice are models for studying altered cholesterol metabolism and oxidative stress onset in the brain. Carbon nanodots are a new
Externí odkaz:
https://doaj.org/article/9322e11882604c4585ba650b964d9d27
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13778 (2022)
The objective of this study was to determine the influence of sex and strain on the dysregulation of trace element concentration and associative gene expression due to diet induced obesity in adipose tissue and the liver. Male and female C57BL/6J (B6
Externí odkaz:
https://doaj.org/article/ddbe8ab7ae7048bfbb9d56a5290a80e8
Publikováno v:
Nutrients, Vol 12, Iss 12, p 3909 (2020)
The aim of this study was to determine the impact of diet-induced obesity (DIO) on trace element homeostasis and gene expression in the olfactory bulb and to identify potential interaction effects between diet, sex, and strain. Our study is based on
Externí odkaz:
https://doaj.org/article/735e7e706fab49079fa8c56232275015
Publikováno v:
Nutritional Neuroscience. 25:2601-2615
BACKGROUND Obesity has been linked to behavioral and biochemical changes, such as reduced physical activity, dysregulated dopamine metabolism, and gene expression alterations in the brain. The impact of a continuous high-fat diet and resulting state
Autor:
Asad A. Aboud, Andrew M. Tidball, Kevin K. Kumar, M. Diana Neely, Bingying Han, Kevin C. Ess, Charles C. Hong, Keith M. Erikson, Peter Hedera, Aaron B. Bowman
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 204-212 (2015)
Poorly-defined interactions between environmental and genetic risk factors underlie Parkinson's disease (PD) etiology. Here we tested the hypothesis that human stem cell derived forebrain neuroprogenitors from patients with known familial risk for ea
Externí odkaz:
https://doaj.org/article/a50689e8e4a94a1bbc251e240c2de139
Autor:
Robert W. Williams, Keith M. Erikson, Carolina Torres-Rojas, Megan K. Mulligan, Wenyuan Zhao, Lu Lu, Daming Zhuang, Byron C. Jones
Publikováno v:
Biometals
One common characteristic of neurodegenerative diseases is dysregulation of iron, usually with observed increases in its concentration in various regions. Heavy alcohol consumption is believed to contribute to such iron dysregulation in the brain wit
Autor:
Aaron B. Bowman, Keith M. Erikson, Daniel O. Claassen, Hakmook Kang, Yan Yan, Melissa Totten, James Silverman, Anna C Pfalzer
Publikováno v:
Scientific Reports. 12
Objective: The importance of metal biology in neurodegenerative diseases such as Huntingtin Disease is well documented with evidence of direct interactions between metals such as copper, zinc, iron and manganese and mutant Huntingtin pathobiology. To