Zobrazeno 1 - 10
of 587
pro vyhledávání: '"Keith M Channon"'
Autor:
Samer Fawaz, Federico Marin, Sarosh A Khan, Rupert F G Simpson, Rafail A Kotronias, Jason Chai, Oxford Acute Myocardial Infarction (OxAMI) Study Investigators, Firas Al-Janabi, Rohan Jagathesan, Klio Konstantinou, Shah R Mohdnazri, Gerald J Clesham, Kare H Tang, Christopher M Cook, Keith M Channon, Adrian P Banning, John R Davies, Grigoris V Karamasis, Giovanni L De Maria, Thomas R Keeble
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 51, Iss , Pp 101374- (2024)
Background: The assessment of coronary microvascular dysfunction (CMD) using invasive methods is a field of growing interest, however the preferred method remains debated. Bolus and continuous thermodilution are commonly used methods, but weak agreem
Externí odkaz:
https://doaj.org/article/659aa0243cca4419aeb5a1ea4af6732d
Autor:
Bashir Alaour, Michael Marber, Keith M Channon, Giovanni Luigi De Maria, John A Henry, Adrian P Banning, Alexander Richard Lyon, Rafail A Kotronias, Liam Steven Couch, James W Garrard, Thomas Edward Kaier
Publikováno v:
Open Heart, Vol 11, Iss 1 (2024)
Objective Takotsubo syndrome (TTS) is an acute heart failure syndrome which resembles acute coronary syndrome (ACS) at presentation. Differentiation requires coronary angiography, but where this does not occur immediately, cardiac biomarkers may prov
Externí odkaz:
https://doaj.org/article/5755a915093149059f1ce1ef4ca63a59
Autor:
Amit Kaura, Adam Hartley, Vasileios Panoulas, Ben Glampson, Anoop S V Shah, Jim Davies, Abdulrahim Mulla, Kerrie Woods, Joe Omigie, Anoop D Shah, Mark R Thursz, Paul Elliott, Harry Hemmingway, Bryan Williams, Folkert W Asselbergs, Michael O'Sullivan, Graham M Lord, Adam Trickey, Jonathan Ac Sterne, Dorian O Haskard, Narbeh Melikian, Darrel P Francis, Wolfgang Koenig, Ajay M Shah, Rajesh Kharbanda, Divaka Perera, Riyaz S Patel, Keith M Channon, Jamil Mayet, Ramzi Khamis
Publikováno v:
PLoS Medicine, Vol 19, Iss 2, p e1003911 (2022)
BackgroundThere is limited evidence on the use of high-sensitivity C-reactive protein (hsCRP) as a biomarker for selecting patients for advanced cardiovascular (CV) therapies in the modern era. The prognostic value of mildly elevated hsCRP beyond tro
Externí odkaz:
https://doaj.org/article/ec5e369770594818bb3c10e2121250ab
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0216315 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0214361.].
Externí odkaz:
https://doaj.org/article/11268ff0b709493e81d6f3d8dbd805fb
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214361 (2019)
Quantifying the value of investment in medical research can inform decision-making on the prioritisation of research programmes. Existing methodologies to estimate the rate of return of medical research are inappropriate for early-phase translational
Externí odkaz:
https://doaj.org/article/058e1b413ce3470c910a2f8ce79115c1
Autor:
Francesca Galassi, Mohammad Alkhalil, Regent Lee, Philip Martindale, Rajesh K Kharbanda, Keith M Channon, Vicente Grau, Robin P Choudhury
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190650 (2018)
Assessment of coronary stenosis severity is crucial in clinical practice. This study proposes a novel method to generate 3D models of stenotic coronary arteries, directly from 2D coronary images, and suitable for immediate assessment of the stenosis
Externí odkaz:
https://doaj.org/article/660feb0b62bd4a9b8d37dd91e76cbe8e
Autor:
Asif J Iqbal, Tessa J Barrett, Lewis Taylor, Eileen McNeill, Arun Manmadhan, Carlota Recio, Alfredo Carmineri, Maximillian H Brodermann, Gemma E White, Dianne Cooper, Joseph A DiDonato, Maryam Zamanian-Daryoush, Stanley L Hazen, Keith M Channon, David R Greaves, Edward A Fisher
Publikováno v:
eLife, Vol 5 (2016)
Apolipoprotein A1 (apoA1) is the major protein component of high-density lipoprotein (HDL) and has well documented anti-inflammatory properties. To better understand the cellular and molecular basis of the anti-inflammatory actions of apoA1, we explo
Externí odkaz:
https://doaj.org/article/4f6ab8947a3d4308a252fadfcd67c3a6
Autor:
Alastair G Kerr, Lawrence CS Tam, Ashley B Hale, Milena Cioroch, Gillian Douglas, Keith M Channon, Richard Wade-Martins
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Familial hypercholesterolemia (FH) is a life-threatening genetic disorder characterized by elevated levels of plasma low-density lipoprotein cholesterol (LDL-cholesterol). Current attempts at gene therapy for FH have been limited by the use of strong
Externí odkaz:
https://doaj.org/article/10e55b5cdf034c57828337d81a073d78
Autor:
Benno Cardini, Katrin Watschinger, Martin Hermann, Peter Obrist, Rupert Oberhuber, Gerald Brandacher, Surawee Chuaiphichai, Keith M Channon, Johann Pratschke, Manuel Maglione, Ernst R Werner
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112570 (2014)
Aim of this study was to identify the nitric oxide synthase (NOS) isoform involved in early microcirculatory derangements following solid organ transplantation.Tetrahydrobiopterin donor treatment has been shown to specifically attenuate these derange
Externí odkaz:
https://doaj.org/article/57dc127f4104480f94112d2c4fca9a70
Autor:
Asif J Iqbal, Daniel Regan-Komito, Ivy Christou, Gemma E White, Eileen McNeill, Amy Kenyon, Lewis Taylor, Theodore S Kapellos, Edward A Fisher, Keith M Channon, David R Greaves
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58744 (2013)
Chemotaxis assays are an invaluable tool for studying the biological activity of inflammatory mediators such as CC chemokines, which have been implicated in a wide range of chronic inflammatory diseases. Conventional chemotaxis systems such as the mo
Externí odkaz:
https://doaj.org/article/fce6674479494768832c2d37a8acafe2