Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Keith M, Derbyshire"'
Autor:
Carol Smith, Jill G Canestrari, Archer J Wang, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade
Publikováno v:
eLife, Vol 11 (2022)
Most bacterial ORFs are identified by automated prediction algorithms. However, these algorithms often fail to identify ORFs lacking canonical features such as a length of >50 codons or the presence of an upstream Shine-Dalgarno sequence. Here, we us
Externí odkaz:
https://doaj.org/article/f95ff1f8c0b54ab4835c1b705bd552f1
Autor:
Soneya Majumdar, Ayush Deep, Manjuli R. Sharma, Jill Canestrari, Melissa Stone, Carol Smith, Ravi K. Koripella, Pooja Keshavan, Nilesh K. Banavali, Joseph T. Wade, Todd A. Gray, Keith M. Derbyshire, Rajendra K. Agrawal
Publikováno v:
bioRxiv
Treatment of tuberculosis continues to be challenging due to the widespread latent form of the disease and the emergence of antibiotic-resistant strains of the pathogen,Mycobacterium tuberculosis. Bacterial ribosomes are a common and effective target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b6a6a1dc1cf2c92d3afa4c053a56ab
https://europepmc.org/articles/PMC10081302/
https://europepmc.org/articles/PMC10081302/
Publikováno v:
J Bacteriol
The genus Mycobacterium contains several slow-growing human pathogens, including Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium. Mycobacterium smegmatis is a nonpathogenic and fast growing species within this genus. In 1990
Autor:
Martina Rofaeil, Keith M. Derbyshire, Joseph T. Wade, Todd A. Gray, Erica Lasek-Nesselquist, Jill G. Canestrari, Matthew M. Champion, Ashutosh Upadhyay
Publikováno v:
Mol Microbiol
Genome-wide transcriptomic analyses have revealed abundant expressed short open reading frames (ORFs) in bacteria. Whether these short ORFs, or the small proteins they encode, are functional remains an open question. One quarter of mycobacterial mRNA
Autor:
Archer J Wang, Jill G Canestrari, Carol Smith, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade
Publikováno v:
eLife. 11
Most bacterial ORFs are identified by automated prediction algorithms. However, these algorithms often fail to identify ORFs lacking canonical features such as a length of >50 codons or the presence of an upstream Shine-Dalgarno sequence. Here, we us
Autor:
Scarlet S Shell, Jing Wang, Pascal Lapierre, Mushtaq Mir, Michael R Chase, Margaret M Pyle, Richa Gawande, Rushdy Ahmad, David A Sarracino, Thomas R Ioerger, Sarah M Fortune, Keith M Derbyshire, Joseph T Wade, Todd A Gray
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005641 (2015)
RNA-seq technologies have provided significant insight into the transcription networks of mycobacteria. However, such studies provide no definitive information on the translational landscape. Here, we use a combination of high-throughput transcriptom
Externí odkaz:
https://doaj.org/article/cc14b07582f341739c4a970a97445956
Autor:
Carol, Smith, Jill G, Canestrari, Archer J, Wang, Matthew M, Champion, Keith M, Derbyshire, Todd A, Gray, Joseph T, Wade
Publikováno v:
eLife. 11
Most bacterial ORFs are identified by automated prediction algorithms. However, these algorithms often fail to identify ORFs lacking canonical features such as a length of50 codons or the presence of an upstream Shine-Dalgarno sequence. Here, we use
Autor:
Daniel A. Russell, J. A. Judd, Alexander Dills, Joseph T. Wade, Jemila C. Kester, M. Mir, Erica Lasek-Nesselquist, E. Dove, Sarah M. Fortune, Rebekah M. Dedrick, Pascal Lapierre, Christopher G Meier, Keith M. Derbyshire, Ian D. Wolf, A. Joseph, Ryan R Clark, M. Stone, Graham F. Hatfull, Jill G. Canestrari, Junhao Zhu, Todd A. Gray, Samantha E. Wirth, Ashutosh Upadhyay, E. R. Rubin, Michael J. Palumbo, Carol Smith
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
Diseases caused by mycobacterial species result in millions of deaths per year globally, and present a substantial health and economic burden, especially in immunocompromised patients. Difficulties inherent in working with mycobacterial pathogens hav
Autor:
Yasu S. Morita, Todd A. Gray, James R Brenner, Sarah M. Fortune, Jemila C. Kester, Ian L Sparks, Keith M. Derbyshire, Julia Puffal, Brittany R Anderson, Alexander Dills, Joseph T. Wade, Julius Judd, Malavika Prithviraj, Corelle A. Z. Rokicki
Publikováno v:
J Bacteriol
Mycobacteria spatially organize their plasma membrane, and many enzymes involved in envelope biosynthesis associate with a membrane compartment termed the intracellular membrane domain (IMD). The IMD is concentrated in the polar regions of growing ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde5a52c8640f36fa0ebc31b89d8ab42
https://doi.org/10.1101/2021.02.17.431749
https://doi.org/10.1101/2021.02.17.431749