Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Keith Leiper"'
Autor:
Jonathan M. Rhodes, Anthony Ellis, Keith Leiper, Kate Martin, Alastair J.M. Watson, A. I. Morris
Publikováno v:
Alimentary Pharmacology & Therapeutics. 27:1233-1239
SUMMARY Background Crohn’s disease is characterized by defective innate immune responses to intestinal bacteria. Clarithromycin is a broad-spectrum antibiotic that has good penetration into macrophages. Aim To assess the efficacy of clarithromycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf3ac5914c0dda41616b36970ceea8a
https://doi.org/10.1111/j.1365-2036.2008.03661.x
https://doi.org/10.1111/j.1365-2036.2008.03661.x
Autor:
Adrian, Thuraisingam, Keith, Leiper
Publikováno v:
Hospital Medicine. 64:703-707
Patients with ulcerative colitis have no increased mortality compared to population controls and the disease can be cured be colectomy. This review concentrates on the medical management of ulcerative colitis including the management of active coliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7ac2ce9532db0e5b34ff11cb949280
https://doi.org/10.12968/hosp.2003.64.12.2360
https://doi.org/10.12968/hosp.2003.64.12.2360
Autor:
Adrian Thuraisingam, Keith Leiper
Publikováno v:
Hospital Medicine. 64:713-718
Current evidence strongly suggests that Crohn's disease is caused by an abnormal response to enteric flora. This review examines the current evidence for medical management of Crohn's disease, particularly focusing on alternative therapies to cortico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d48ffe9d1c9cb50134d2393599470d
https://doi.org/10.12968/hosp.2003.64.12.2362
https://doi.org/10.12968/hosp.2003.64.12.2362
Autor:
Jeremy D. Milton, Michael D. Jenkinson, Lu-Gang Yu, Barry J. Campbell, Jane Democratis, Jonathan M. Rhodes, Keith Leiper
Publikováno v:
Clinical Science. 101:395-402
Goblet cell depletion occurs in various forms of colitis, but its mechanism is unknown. We have investigated two linked hypotheses: (i) that bacterial peptides, such as formyl-methionyl-leucyl-phenylalanine (fMLP), interact with epithelial cells indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0d1a8f4737ce4509606cc3d2832ec5
https://doi.org/10.1042/cs1010395
https://doi.org/10.1042/cs1010395
Publikováno v:
Glycobiology. 11:385-393
Mucins in ulcerative colitis and colon cancer share common properties of reduced sulfation and increased oncofetal carbohydrate antigen expression. It has previously been shown that there is no simple correlation between these changes and the activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe2f1c380ffd64f3c56821c8727e9f9
https://doi.org/10.1093/glycob/11.5.385
https://doi.org/10.1093/glycob/11.5.385
Publikováno v:
Alimentary Pharmacology & Therapeutics. 14:801-806
Background: Crohn’s disease seems likely to be due in some way to bacteria. Clarithromycin is a broad spectrum macrolide antibiotic with good penetration into macrophages and may be effective in eradicating the organisms that are presumed to be at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad233c83b09cae0d4d7fadf2df25d0e9
https://doi.org/10.1046/j.1365-2036.2000.00753.x
https://doi.org/10.1046/j.1365-2036.2000.00753.x
Publikováno v:
Baillière's Clinical Gastroenterology. 12:179-199
About 90% of patients with Crohn's disease require surgery at some time in their lives but the clinical recurrence rate after surgery is about 50% within 5 years, with 50% requiring further surgery within 10 years. Endoscopic evidence of relapse can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d4f98ceb2f15d147c6223725e8deef
https://doi.org/10.1016/s0950-3528(98)90092-6
https://doi.org/10.1016/s0950-3528(98)90092-6
Publikováno v:
Baillière's Clinical Gastroenterology. 11:129-151
Prompt diagnosis and exclusion of infection requires a minimum of rigid sigmoidoscopy, rectal mucosal biopsy and stool culture. Admission to hospital is mandatory for patients with features of severe disease, or who are in their first attack of ulcer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::542cb6e577f2d6f081f9816f2864db2f
https://doi.org/10.1016/s0950-3528(97)90058-0
https://doi.org/10.1016/s0950-3528(97)90058-0
Autor:
Andrew R. Moore, Keith Leiper
Publikováno v:
Textbook of Clinical Gastroenterology and Hepatology, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716bc80868226f145f6d50619bca020e
https://doi.org/10.1002/9781118321386.ch116
https://doi.org/10.1002/9781118321386.ch116
Publikováno v:
Clinical Dilemmas in Inflammatory Bowel Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398ccf4ff6a204923e2d139cd6a10bd3
https://doi.org/10.1002/9781444342574.ch50
https://doi.org/10.1002/9781444342574.ch50