Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Keith L. Wycoff"'
Autor:
Smrithi S. Menon, Galia Ramirez-Toloza, Keith L. Wycoff, Sean Ehinger, Jutamas Shaughnessy, Sanjay Ram, Viviana P. Ferreira
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chagas disease, a chronic disabling disease caused by the protozoan Trypanosoma cruzi, has no standardized treatment or preventative vaccine. The infective trypomastigote form of T. cruzi is highly resistant to killing by the complement immune system
Externí odkaz:
https://doaj.org/article/3047238984774b099d5e0b38bcbabb1d
Autor:
Jutamas Shaughnessy, Aleyo Chabeda, Y. Tran, Bo Zheng, Nancy Nowak, Carolynn Steffens, Rosane B. DeOliveira, Sunita Gulati, Lisa A. Lewis, James Maclean, John A. Moss, Keith L. Wycoff, Sanjay Ram
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Novel therapeutics against the global threat of multidrug-resistant Neisseria gonorrhoeae are urgently needed. Gonococci evade killing by complement by binding factor H (FH), a key inhibitor of the alternative pathway. FH comprises 20 short consensus
Externí odkaz:
https://doaj.org/article/f3abdcbc9c494fb6ab5c5b211e92670a
Autor:
Jutamas Shaughnessy, Y Tran, Bo Zheng, Rosane B. DeOliveira, Sunita Gulati, Wen-Chao Song, James M. Maclean, Keith L. Wycoff, Sanjay Ram
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Novel therapeutics against the global threat of multidrug-resistant Neisseria gonorrhoeae are urgently needed. Gonococci possess several mechanisms to evade killing by human complement, including binding of factor H (FH), a key inhibitor of the alter
Externí odkaz:
https://doaj.org/article/1c13c13128da4d2cb904412b3b9b4e14
Autor:
Smrithi Sugumaran Menon, Galia Ramirez-Toloza, Keith L. Wycoff, Jutamas Shaughnessy, Sanjay Ram, Viviana P. Ferreira
Publikováno v:
The Journal of Immunology. 208:170.20-170.20
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi (T. cruzi). Complement (C) is a critical arm of the immune system. Various pathogens, including T. cruzi, hijack host regulators such as Factor H (FH) to inactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d78faf7b84d9eda1f728d18ca4c1b631
https://doi.org/10.4049/jimmunol.208.supp.170.20
https://doi.org/10.4049/jimmunol.208.supp.170.20
Publikováno v:
The Journal of Immunology. 208:181.02-181.02
Background As a major cause of a myriad of superficial and invasive infections worldwide, Staphylococcus aureus is a master of immune evasion, with the complement system being a primary target. Previously, we have shown that S. aureus surface protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9fadc5358e09f6b8fde768909c6168f
https://doi.org/10.4049/jimmunol.208.supp.181.02
https://doi.org/10.4049/jimmunol.208.supp.181.02
Autor:
Megan A. G. Sage, Katelyn D. Cranmer, Michele L. Semeraro, Shelby Ma, Elena V. Galkina, Y. Tran, Keith L. Wycoff, Julia A. Sharp
Publikováno v:
PLOS ONE. 17:e0265774
Staphylococcus aureus employs a multitude of immune-evasive tactics to circumvent host defenses including the complement system, a component of innate immunity central to controlling bacterial infections. With antibiotic resistance becoming increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4576b830a7bcf41ecceb02023030d40
https://doi.org/10.1371/journal.pone.0265774
https://doi.org/10.1371/journal.pone.0265774
Autor:
Rosane B. DeOliveira, Jutamas Shaughnessy, Y. Tran, Keith L. Wycoff, James Maclean, Bo Zheng, Wen-Chao Song, Sunita Gulati, Sanjay Ram
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Novel therapeutics against the global threat of multidrug-resistant Neisseria gonorrhoeae are urgently needed. Gonococci possess several mechanisms to evade killing by human complement, including binding of factor H (FH), a key inhibitor of the alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2da69172c0813ab6d7328cb548fbbd
http://europepmc.org/articles/PMC7649208
http://europepmc.org/articles/PMC7649208
INTRODUCTION: The poor prognosis of GBM reflects its capacity to supplement proliferative programs with pro-tumoral interactions with the microenvironment, including invasion and immunosuppression. There is a need to simultaneously target these proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6da9ad4e57fa4f872f26dd89591e5dd
https://europepmc.org/articles/PMC6216865/
https://europepmc.org/articles/PMC6216865/
Autor:
Laurence M. Brill, Keith L. Wycoff
Publikováno v:
Molecular Methods in Plant Pathology ISBN: 9780203746523
This chapter reviews advances in the study of plant disease brought about by using monoclonal antibodies raised against fungi. It also reviews the use of monoclonal antibodies in plant disease research. Successful detection and quantitation of fungal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39001190227feb5afca3ac1fb92cec7
https://doi.org/10.1201/9780203746523-27
https://doi.org/10.1201/9780203746523-27
Autor:
Elodie Weider, Surendra Nimesh, Marie-Claude Asselin, Delia Susan-Resiga, Yahya Ashraf, Keith L. Wycoff, Nabil G. Seidah, Jianbing Zhang, Josée Hamelin, Annik Prat, Rachid Essalmani
Publikováno v:
The Journal of biological chemistry. 291(32)
Single domain antibodies (sdAbs) correspond to the antigen-binding domains of camelid antibodies. They have the same antigen-binding properties and specificity as monoclonal antibodies (mAbs) but are easier and cheaper to produce. We report here the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48392afff5f69b3f0cb3bf6c9f9fbc24
https://pubmed.ncbi.nlm.nih.gov/27986868
https://pubmed.ncbi.nlm.nih.gov/27986868