Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Keith Knutson"'
Autor:
Hemang Yadav, MBBS, Laurie A. Meade, RN, Rickey E. Carter, PhD, Keith Knutson, PhD, Ognjen Gajic, MD, Daryl J. Kor, MD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 7, p e0728 (2022)
IMPORTANCE:. Animal models and limited human studies have suggested a plausible role for platelets in the pathogenesis and resolution of acute respiratory distress syndrome (ARDS). However, there are little data regarding the role of platelets in ARD
Externí odkaz:
https://doaj.org/article/768b42ae47ed4d44929d492f7e59aac0
Autor:
Emmanuel Gabriel, Minhyung Kim, Daniel Fisher, Catherine Mangum, Kristopher Attwood, Wenyan Ji, Debabrata Mukhopadhyay, Sanjay Bagaria, Matthew Robertson, Tri Dinh, Keith Knutson, Joseph Skitzki, Michael Wallace
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 39-39 (2021)
ABSTRACT IMPACT: Investigation of tumor-associated blood vessels may serve as an imaging biomarker of response to systemic therapy and cancer outcomes. OBJECTIVES/GOALS: Aberrancies in the tumor microvasculature limit the systemic delivery of antican
Externí odkaz:
https://doaj.org/article/5d787cc07af34c52a22e87793e3339bc
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 6-6 (2020)
OBJECTIVES/GOALS: Our overall objective is to develop a directly observable and reproducible method of enhanced blood flow through tumor vessels (i.e. dynamic control) at the time of systemic treatment delivery. Our central hypothesis is that the dyn
Externí odkaz:
https://doaj.org/article/ba51f9b522454875bffd154a26129dca
Autor:
Brett D Shepard, Davide De Forni, David R McNamara, Andrea Foli, Stacey A Rizza, Roshini S Abraham, Keith Knutson, Peter J Wettstein, Franco Lori, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3096 (2008)
During uncontrolled HIV disease, both TNF-related apoptosis inducing ligand (TRAIL) and TRAIL receptor expression are increased. Enhanced TRAIL sensitivity is due to TRAIL receptor up-regulation induced by gp120. As a result of successful antiretrovi
Externí odkaz:
https://doaj.org/article/7c716647a9ab4942bd2923f33ba0cdf0
Autor:
Amy Degnim, Robert Vierkant, Stacey Winham, Marlene Frost, Daniel Visscher, Jodi Carter, Suneetha Kaggal, Julie Cunningham, Teresa Allers, Tanya Hoskin, Ethan Heinzen, Celine Vachon, Keith Knutson, Derek Radisky, Mark Sherman
Publikováno v:
Cancer Research. 80:P5-08
Background Prior epidemiologic studies have shown an inverse relationship of aspirin and NSAID use with breast cancer (BC) risk in the general population. Women with benign breast disease (BBD) are at an increased BC risk compared with women in the g
Autor:
Emmanuel M. Gabriel, Brian Necela, Deborah Bahr, Jamie Kaplan, Kristopher Attwood, Keith Knutson
Publikováno v:
Cancer Research. 82:5371-5371
INTRODUCTION: HER2/neu is a potent biomarker for which anti-HER2/neu antibodies offer significant responses. However, many cancers, such as melanoma, have less than 5% expression of HER2/neu. The purpose of this study was to determine whether induced
Autor:
Emmanuel M. Gabriel, Vijay Madamsetty, Deborah Bahr, Jamie Kaplan, Kristopher Attwood, Sanjay Bagaria, Keith Knutson, Debabrata Mukhopadhyay
Publikováno v:
Cancer Research. 82:5071-5071
INTRODUCTION: Intratumoral phenylephrine (α1 vasoconstrictor) combined with chemotherapy has been used for cutaneous malignancies with modest local response. The purpose of this study was to improve the efficacy of intratumoral melphalan using susta
Autor:
Saranya Chumsri, Jun He, David Hillman, Morgan Weidner, Dana Haley, Aline Reis, Kathleen Tenner, Pooja Advani, Kostandinos Sideras, Alvaro Moreno-Aspitia, Edith Perez, Keith Knutson
Publikováno v:
Cancer Research. 81:CT133-CT133
Background: A previous neoadjuvant study in patients with triple negative breast cancer (TNBC) demonstrated that low tumor infiltrating lymphocytes (TILs) after neoadjuvant chemotherapy is associated with a poor outcome. Activation of RAS/MAPK pathwa
Autor:
Doug Hinerfeld, Keith Knutson, Derek Radisky, E. Aubrey Thompson, Yan Asmann, Kim McCoy, Amy Degnim, Jodi Carter, Stacey Winham, Michele Cote, Jeroen van der Laak, Mark Sherman
Publikováno v:
Cancer Research. 79:651-651
Existing risk models underperform among women who have undergone a benign breast disease (BBD) biopsy (> one million performed annually in the US) and with respect to estimating the risk of aggressive BCs. We've shown that molecular pathologic analys
Autor:
Lavakumar Karyampudi, Purushottam Lamichhane, James krempski, Kimberly Kalli, Marshall Behrens, Doris Vargas, Lynn Hartmann, Jo Marie Janco, Karen Hedin, Allan Dietz, Ellen Goode, Keith Knutson
Publikováno v:
The Journal of Immunology. 194:70.5-70.5
The PD-1:PD-L1 axis is a major immune regulatory pathway that blunts T cell activation in the tumor microenvironment. We recently identified that PD-1 is also upregulated on ovarian mouse tumor-infiltrating myeloid dendritic cells (TIDCs) that exhibi